Patents by Inventor Kentaro Abe

Kentaro Abe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250285784
    Abstract: An insulated wire includes a linear conductor insulative coated with an insulator made of thermoplastic polyurethane as an outermost layer, and a plurality of wavy irregularities provided on a surface of the insulator along a direction perpendicular to a longitudinal direction of the insulated wire, and an arithmetic mean height Sa of the surface of the insulator is 4.4 ?m or more and 12 ?m or less. A structure includes the insulated wire and a component made of ethylene propylene rubber, bonded to the surface of the insulator of the insulated wire by an adhesive.
    Type: Application
    Filed: February 28, 2025
    Publication date: September 11, 2025
    Inventors: Tetsuro SATO, Satoru OUCHI, Kentaro ABE
  • Patent number: 12372421
    Abstract: A pressure sensitive sensor includes: a first conductive member formed into a long shape, the first conductive member having conductivity and elasticity; a second conductive member internally including a long space to arrange the first conductive member, the second conductive member having conductivity and elasticity; and an insulating member having an insulating property and elasticity, the insulating member holding the first conductive member to separate the first conductive member from the second conductive member, the insulating member being movable relative to one or both of the first conductive member and the second conductive member.
    Type: Grant
    Filed: February 12, 2024
    Date of Patent: July 29, 2025
    Assignee: Proterial, Ltd.
    Inventors: Keisuke Sugita, Kentaro Abe, Tomomi Onose, Taichi Oka, Manabu Kako
  • Publication number: 20250179553
    Abstract: An evaluation apparatus includes an acquiring unit configured to acquire information on a change amount of an absorbance per unit time. The change amount is obtained by a measurement method including causing a peroxidase to act on hydrogen peroxide, which is produced by solubilizing a low-density lipoprotein (LDL) in a specimen with a surfactant that acts on the LDL, and subjecting the resultant to an oxidation reaction with a cholesterol oxidase, to introduce the hydrogen peroxide to a color reaction, followed by measurement of a change of the absorbance with time. The evaluation apparatus also includes an evaluating unit configured to evaluate an amount of an oxidized LDL in the specimen based on the change amount.
    Type: Application
    Filed: November 29, 2024
    Publication date: June 5, 2025
    Inventors: Yasutoshi Kashiwagi, Kentaro Abe, Akinori Tanimizu
  • Patent number: 12253515
    Abstract: Provided are an expression inhibitor of a cancer promoting factor based on the discovery of a new factor influencing the expression amount/level of a cancer promoting factor, and a development tool therefor. Provided are also a diagnostic agent and a diagnosis method for cancer. More specifically provided are: an expression inhibitor of a cancer promoting factor containing at least one kind of inhibitor selected from the group consisting of RBMS expression inhibitor and RBMS function inhibitor; a screening method using as an indicator the expression or the function of RBMS; an expression cassette useful for the method; as well as a diagnostic agent containing a product detection agent for RBMS gene expression and cancer detection method using as an indicator RBMS gene expression amount/level.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: March 18, 2025
    Assignees: National University Corporation Tokyo Medical and Dental University, Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Asahara, Tomoki Chiba, Kentaro Abe
  • Patent number: 12066429
    Abstract: Provided are an expression inhibitor of an inflammation promoting factor based on the discovery of a new factor influencing the expression amount/level of an inflammation promoting factor, and a development tool therefor. Provided are also a diagnostic agent and a diagnosis method for immune diseases, inflammatory diseases, painful conditions and similar. More specifically provided are: an expression inhibitor of an inflammation promoting factor containing at least one kind of inhibitor selected from the group consisting of RBMS2 expression inhibitor and RBMS2 function inhibitor; a screening method using as an indicator the expression or the function of RBMS2; an expression cassette useful for the method; as well as a diagnostic agent containing a product detection agent for RBMS2 gene expression and disease detection method using as an indicator RBMS2 gene expression amount/level.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: August 20, 2024
    Assignees: National University Corporation Tokyo Medical and Dental University, Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Asahara, Tomoki Chiba, Kentaro Abe
  • Publication number: 20240183725
    Abstract: A pressure sensitive sensor includes: a first conductive member formed into a long shape, the first conductive member having conductivity and elasticity; a second conductive member internally including a long space to arrange the first conductive member, the second conductive member having conductivity and elasticity; and an insulating member having an insulating property and elasticity, the insulating member holding the first conductive member to separate the first conductive member from the second conductive member, the insulating member being movable relative to one or both of the first conductive member and the second conductive member.
    Type: Application
    Filed: February 12, 2024
    Publication date: June 6, 2024
    Inventors: Keisuke SUGITA, Kentaro ABE, Tomomi ONOSE, Taichi OKA, Manabu KAKO
  • Patent number: 11933682
    Abstract: A pressure sensitive sensor includes: a first conductive member formed into a long shape, the first conductive member having conductivity and elasticity; a second conductive member internally including a long space to arrange the first conductive member, the second conductive member having conductivity and elasticity; and an insulating member having an insulating property and elasticity, the insulating member holding the first conductive member to separate the first conductive member from the second conductive member, the insulating member being movable relative to one or both of the first conductive member and the second conductive member.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: March 19, 2024
    Assignee: Proterial, Ltd.
    Inventors: Keisuke Sugita, Kentaro Abe, Tomomi Onose, Taichi Oka, Manabu Kako
  • Patent number: 11927510
    Abstract: A standard calibration solution includes water, a non-alcoholic solvent that is mixed with water, and a steroid hormone, and a content of the non-alcoholic solvent is 10% by volume or more and 50% by volume or less. The standard calibration solution is used for quantitative measurement using a mass spectrometry device.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: March 12, 2024
    Assignee: JEOL Ltd.
    Inventors: Masaki Takiwaki, Seketsu Fukuzawa, Yoshikuni Kikutani, Kiyotaka Fujino, Kentaro Abe, Yoshiyuki Ito
  • Publication number: 20220236122
    Abstract: A pressure sensitive sensor includes: a first conductive member formed into a long shape, the first conductive member having conductivity and elasticity; a second conductive member internally including a long space to arrange the first conductive member, the second conductive member having conductivity and elasticity; and an insulating member having an insulating property and elasticity, the insulating member holding the first conductive member to separate the first conductive member from the second conductive member, the insulating member being movable relative to one or both of the first conductive member and the second conductive member.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 28, 2022
    Inventors: Keisuke SUGITA, Kentaro ABE, Tomomi ONOSE, Taichi OKA, Manabu KAKO
  • Patent number: 11217400
    Abstract: A pressure-sensitive sensor, includes a hollow tubular member including an elastic insulating material; and n electrode wires (n being an integer of not less than 3) arranged away from one another and held inside the tubular member, wherein when an external pressure is applied to the tubular member, the tubular member elastically deforms such that at least two of the n electrode wires contact with each other, and wherein the n electrode wires extend linearly and parallel to a central axis of the tubular member.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: January 4, 2022
    Assignee: HITACHI METALS, LTD.
    Inventors: Keisuke Sugita, Satoru Ouchi, Kentaro Abe
  • Publication number: 20210156770
    Abstract: A standard calibration solution includes water, a non-alcoholic solvent that is mixed with water, and a steroid hormone, and a content of the non-alcoholic solvent is 10% by volume or more and 50% by volume or less. The standard calibration solution is used for quantitative measurement using a mass spectrometry device.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 27, 2021
    Inventors: Masaki Takiwaki, Seketsu Fukuzawa, Yoshikuni Kikutani, Kiyotaka Fujino, Kentaro Abe, Yoshiyuki Ito
  • Publication number: 20200386741
    Abstract: Provided are an expression inhibitor of an inflammation promoting factor based on the discovery of a new factor influencing the expression amount/level of an inflammation promoting factor, and a development tool therefor. Provided are also a diagnostic agent and a diagnosis method for immune diseases, inflammatory diseases, painful conditions and similar. More specifically provided are: an expression inhibitor of an inflammation promoting factor containing at least one kind of inhibitor selected from the group consisting of RBMS2 expression inhibitor and RBMS2 function inhibitor; a screening method using as an indicator the expression or the function of RBMS2; an expression cassette useful for said method; as well as a diagnostic agent containing a product detection agent for RBMS2 gene expression and disease detection method using as an indicator RBMS2 gene expression amount/level.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 10, 2020
    Applicants: National University Corporation Tokyo Medical and Dental University, Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Hiroshi ASAHARA, Tomoki CHIBA, Kentaro ABE
  • Publication number: 20200355672
    Abstract: Provided are an expression inhibitor of a cancer promoting factor based on the discovery of a new factor influencing the expression amount/level of a cancer romoting factor, and a development tool therefor. Provided are also a diagnostic agent and a diagnosis method for cancer. More specifically provided are: an expression inhibitor of a cancer promoting factor containing at least one kind of inhibitor selected from the group consisting of RBMS expression inhibitor and RBMS function inhibitor; a screening method using as an indicator the expression or the function of RBMS; an expression cassette useful for said method; as well as a diagnostic agent containing a product detection agent for RBMS gene expression and cancer detection method using as an indicator RBMS gene expression amount/level.
    Type: Application
    Filed: November 9, 2018
    Publication date: November 12, 2020
    Applicants: National University Corporation Tokyo Medical and Dental University, Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Asahara, Tomoki Chiba, Kentaro Abe
  • Publication number: 20200203091
    Abstract: A pressure-sensitive sensor, includes a hollow tubular member including an elastic insulating material; and n electrode wires (n being an integer of not less than 3) arranged away from one another and held inside the tubular member, wherein when an external pressure is applied to the tubular member, the tubular member elastically deforms such that at least two of the n electrode wires contact with each other, and wherein the n electrode wires extend linearly and parallel to a central axis of the tubular member.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Inventors: Keisuke SUGITA, Satoru OUCHI, Kentaro ABE
  • Patent number: 10622167
    Abstract: A pressure-sensitive sensor includes a hollow tubular member including an elastic insulating material, and n electrode wires (n being an integer of not less than 3) arranged away from one another and held inside the tubular member. When an external pressure is applied to the tubular member, the tubular member elastically deforms such that at least two of the n electrode wires contact with each other. The n electrode wires extend linearly and parallel to a central axis of the tubular member.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: April 14, 2020
    Assignee: HITACHI METALS, LTD.
    Inventors: Keisuke Sugita, Satoru Ouchi, Kentaro Abe
  • Publication number: 20190242875
    Abstract: Provided are an expression inhibitor of an inflammation promoting factor based on the discovery of a new factor influencing the expression amount/level of an inflammation promoting factor, and a development tool therefor. Provided are also a diagnostic agent and a diagnosis method for immune diseases, inflammatory diseases, painful conditions and similar. More specifically provided are: an expression inhibitor of an inflammation promoting factor containing at least one kind of inhibitor selected from the group consisting of RBMS2 expression inhibitor and RBMS2 function inhibitor; a screening method using as an indicator the expression or the function of RBMS2; an expression cassette useful for said method; as well as a diagnostic agent containing a product detection agent for RBMS2 gene expression and disease detection method using as an indicator RBMS2 gene expression amount/level.
    Type: Application
    Filed: May 10, 2017
    Publication date: August 8, 2019
    Applicants: National University Corporation Tokyo Medical and Dental University, Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Hiroshi ASAHARA, Tomoki CHIBA, Kentaro ABE
  • Publication number: 20180182570
    Abstract: A pressure-sensitive sensor includes a hollow tubular member including an elastic insulating material, and n electrode wires (n being an integer of not less than 3) arranged away from one another and held inside the tubular member. When an external pressure is applied to the tubular member, the tubular member elastically deforms such that at least two of the n electrode wires contact with each other. The n electrode wires extend linearly and parallel to a central axis of the tubular member.
    Type: Application
    Filed: December 14, 2017
    Publication date: June 28, 2018
    Inventors: Keisuke Sugita, Satoru Ouchi, Kentaro Abe
  • Patent number: 9557327
    Abstract: An object of the present invention is to provide DNA which regulates the expression of miR-140, a reporter vector which contains the DNA, cells and animals into which the reporter vector is introduced and a screening system for drugs which control the expression of miR-140 and is also to contribute in the development of new therapeutic agents for cartilage diseases such as osteoarthritis and intervertebral disk degeneration using the screening system. The DNA sequence according to the present invention is able to express any gene in a site where miR-140 is expressed and, in addition, it is also able to be utilized for screening a drug which regulates the expression of miR-140. Moreover, the drug that is selected by the screening system of the present invention is expected as a therapeutic agent for cartilage diseases accompanied by abnormality of cartilage.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: January 31, 2017
    Assignees: NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroshi Asahara, Satoshi Yamashita, Mitsuru Naiki, Kentaro Abe
  • Patent number: 9271514
    Abstract: A frozen dessert improved in shape retention without an adverse effect on the properties of the frozen dessert such as viscosity, texture and flavor is provided. The frozen dessert contains plant-derived microfibrillated cellulose.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: March 1, 2016
    Assignees: Kyoto University, Nissei Company, Ltd.
    Inventors: Hiroyuki Yano, Kentaro Abe, Takeshi Nakatani, Yasuo Kase, Shojiro Kikkawa, Yuka Onishi
  • Patent number: 9231386
    Abstract: An electric cable cutter used with a hand-held tool includes a housing; a pair of cutting blades supported by the housing; a pair of orthogonal gears; a drive shaft with an eccentric shaft portion attached to an output gear of the pair of orthogonal gears; a differential gear mechanism which decelerates a rotation of the drive shaft; and an Oldham coupling which corrects an eccentric rotation of an output gear of the differential gear mechanism. A circular-arc-shaped outer surface of the one cutting blade is supported by the other cutting blade so as to be openable and closable. The pair of cutting blades is provided with an outer toothed portion engaging with an output gear of the Oldham coupling. An input gear of the pair of orthogonal gears is connected through an adapter pin to the hand-held tool attachable and detachable through a one-touch operation.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: January 5, 2016
    Assignee: TOA INTERSYSTEM INC.
    Inventors: Minoru Kochi, Sadayoshi Kobayashi, Kentaro Abe