Patents by Inventor Kentaro Fujimoto
Kentaro Fujimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10799866Abstract: Provided is a microfluidic chip. A microfluidic chip includes a main body portion and a first plunger. The main body portion includes a first fluid space for containing a first fluid and a first micro flow channel that is in communication with the first fluid space. The first plunger is capable of movement in the first fluid space so as to deliver the first fluid from the first fluid space to the first micro flow channel. According to the first aspect, a first fluid space for containing a first fluid such as a testing solution and a first plunger that delivers the first fluid from the first fluid space are provided. That is, a syringe composed of the first fluid space and the first plunger is provided, and it is therefore possible to deliver the first fluid by operating the syringe.Type: GrantFiled: July 21, 2017Date of Patent: October 13, 2020Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro Fujimoto
-
Patent number: 10011691Abstract: A fluororubber molded product according to the present invention is obtained by the steps of molding and crosslinking a fluororubber composition and thereafter immersing the composition in a fluorocarbon or an aqueous solution containing a fluorocarbon at a concentration of not less than 10% by volume.Type: GrantFiled: February 17, 2015Date of Patent: July 3, 2018Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro Fujimoto
-
Publication number: 20180043358Abstract: Provided is a microfluidic chip. A microfluidic chip includes a main body portion and a first plunger. The main body portion includes a first fluid space for containing a first fluid and a first micro flow channel that is in communication with the first fluid space. The first plunger is capable of movement in the first fluid space so as to deliver the first fluid from the first fluid space to the first micro flow channel. According to the first aspect, a first fluid space for containing a first fluid such as a testing solution and a first plunger that delivers the first fluid from the first fluid space are provided. That is, a syringe composed of the first fluid space and the first plunger is provided, and it is therefore possible to deliver the first fluid by operating the syringe.Type: ApplicationFiled: July 21, 2017Publication date: February 15, 2018Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro FUJIMOTO
-
Publication number: 20170268494Abstract: A fluororubber tube is provided, which is formed from a rubber composition containing a fluororubber, and not less than 3.8 parts by mass and not greater than 4.1 parts by mass of a polyol crosslinking agent and not less than 3 parts by mass and not greater than 7 parts by mass of a carbon black based on 100 parts by mass of the fluororubber. Thus, the fluororubber tube is made less tacky by suppressing the intrinsic adhesiveness of the crosslinked fluororubber without formation of a coating film which may otherwise complicate the structure of the tube and the production process of the tube or may result in contamination.Type: ApplicationFiled: February 17, 2017Publication date: September 21, 2017Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventors: Kentaro FUJIMOTO, Takeshi ISHIMARU
-
Publication number: 20170261134Abstract: A rubber tube has an inner surface at least partly roughed so that the ratio (Rz/D) of the maximum height Rz of the inner surface to the inner diameter D of the tube is not less than 0.038. The ratio (Rp/D) of the maximum peak height Rp of the inner surface to the inner diameter D of the tube may be not less than 0.019. The ratio (Rv/D) of the maximum valley depth Rv of the inner surface to the inner diameter D of the tube may be not less than 0.019. The ratio (Ra/D) of the arithmetic average roughness Ra of the inner surface to the inner diameter D of the tube may be not less than 0.0036. The ratio (Rq/D) of the root mean square height Rq of the inner surface to the inner diameter D of the tube maybe not less than 0.0046. Thus, the rubber tube has a reduced adhesiveness.Type: ApplicationFiled: February 21, 2017Publication date: September 14, 2017Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventors: Kentaro FUJIMOTO, Takeshi ISHIMARU
-
Publication number: 20160040804Abstract: A pinch valve tube includes a fluororubber tube, the entirety of which is formed integrally of fluororubber and having an internal cavity arranged as a flow passage for a fluid, and a crosslink density of the fluororubber forming an inner surface of the flow passage is made higher than an average crosslink density of the entirety.Type: ApplicationFiled: August 10, 2015Publication date: February 11, 2016Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro FUJIMOTO
-
Publication number: 20150252151Abstract: A fluororubber molded product according to the present invention is obtained by the steps of molding and crosslinking a fluororubber composition and thereafter immersing the composition in a fluorocarbon or an aqueous solution containing a fluorocarbon at a concentration of not less than 10% by volume.Type: ApplicationFiled: February 17, 2015Publication date: September 10, 2015Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro FUJIMOTO
-
Patent number: 8822670Abstract: A method of synthesizing a cDNA chain using an insoluble carrier having on the surface thereof a polymer substance containing a first unit having a group derived from a phosphoric ester composing the hydrophilic portion of phospholipid, and a second unit having a group derived from carboxylic acid having an electron-attractive substituent bound to a carbonyl group, which includes immobilizing a polynucleotide for DNA elongation; bringing a solution containing an RNA fragment, nucleotide monomers, and a reverse transcriptase or an enzyme having polymerase activity into contact with the surface of the insoluble carrier; and allowing the polynucleotide for DNA elongation immobilized on the surface of the carrier to elongate using the RNA fragment contained in the solution as a template, to thereby form a single-strand cDNA.Type: GrantFiled: August 9, 2006Date of Patent: September 2, 2014Assignees: Sumitomo Bakelite Company, Ltd., Kenji KinoshitaInventors: Kenji Kinoshita, Toru Yakabe, Kentaro Fujimoto, Kanehisa Yokoyama, Kazuhiko Fujiwara
-
Patent number: 8435742Abstract: [Object] It is to provide a method and a kit capable of detecting or quantifying a target RNA simply and rapidly from trace amounts of RNA in a sample, in a case such as when one or more kinds of pathogenic microorganisms are to be detected or quantified. [Solving Means] The method comprises the steps of 1) synthesizing cDNA from a sample containing the target RNA using a liquid-phase primer having a promoter sequence and a reverse transcriptase to obtain a cDNA-RNA complex, 2) degrading the RNA of the complex, 3) synthesizing a double-stranded DNA via the cDNA obtained in the step 2) and the solid-phase primer, 4) synthesizing RNA from the double-stranded DNA, 5) synthesizing cDNA via the RNA obtained in the step 4) and the solid-phase primer to obtain a cDNA-RNA complex, 6) degrading the RNA of the complex obtained in step 5), 7) synthesizing a double-stranded DNA via the cDNA obtained in the step 6) and the liquid-phase primer, and 8) quantifying the double-stranded DNAs obtained in the steps 3) and 7).Type: GrantFiled: November 4, 2008Date of Patent: May 7, 2013Assignee: Yamaguchi UniversityInventors: Mutsunori Shirai, Hajime Fukunaga, Kazuhiko Fujiwara, Kanehisa Yokoyama, Kentaro Fujimoto
-
Patent number: 8088580Abstract: The present invention provides an RNA detection method detecting, from a reaction system containing a target sample, a target RNA chain originated from the target sample, using a surface having on the surface thereof a polymer substance which contains a first unit having a group derived from a phosphate ester composing the hydrophilic portion of a phospholipid and a second unit having a carboxylic acid derivative group composed of an electron-attractive substitutional group bound to a carbonyl group, while being provided with at least one reaction space, the reaction space having an immobilized nucleic acid primer immobilized therein.Type: GrantFiled: June 1, 2007Date of Patent: January 3, 2012Assignee: Sumitomo Bakelite Company, Ltd.Inventors: Kenji Kinoshita, Kanehisa Yokoyama, Kentaro Fujimoto, Toru Yakabe, Shin Saito, Kazuhiko Fujiwara
-
Patent number: 7968290Abstract: A method of detecting a gene including immobilizing a primer for DNA elongation onto an insoluble carrier having on the surface thereof a polymer substance containing a first unit having a phosphorylcholine group and a second unit having a carboxylic acid-derived group having an electron-attractive substituent bound to a carbonyl group; annealing the template DNA fragments or RNA fragments with the primer for DNA elongation, so as to elongate the DNA primer while incorporating therein an enzyme, thereby allowing coloration of a chromogenic reagent by its enzymatic action; and judging whether the DNA fragments or RNA fragments of the gene presents or not, based on the degree of coloration.Type: GrantFiled: May 16, 2006Date of Patent: June 28, 2011Assignee: Sumitomo Bakelite Co., Ltd.Inventors: Kenji Kinoshita, Kazuhiko Fujiwara, Kanehisa Yokoyama, Kentaro Fujimoto, Toru Yakabe
-
Publication number: 20110053150Abstract: [Object] It is to provide a method and a kit capable of detecting or quantifying a target RNA simply and rapidly from trace amounts of RNA in a sample, in a case such as when one or more kinds of pathogenic microorganisms are to be detected or quantified. [Solving Means] The method comprises the steps of 1) synthesizing cDNA from a sample containing the target RNA using a liquid-phase primer having a promoter sequence and a reverse transcriptase to obtain a cDNA-RNA complex, 2) degrading the RNA of the complex, 3) synthesizing a double-stranded DNA via the cDNA obtained in the step 2) and the solid-phase primer, 4) synthesizing RNA from the double-stranded DNA, 5) synthesizing cDNA via the RNA obtained in the step 4) and the solid-phase primer to obtain a cDNA-RNA complex, 6) degrading the RNA of the complex obtained in step 5), 7) synthesizing a double-stranded DNA via the cDNA obtained in the step 6) and the liquid-phase primer, and 8) quantifying the double-stranded DNAs obtained in the steps 3) and 7).Type: ApplicationFiled: November 4, 2008Publication date: March 3, 2011Applicant: YAMAGUCHI UNIVERSITYInventors: Mutsunori Shirai, Hajime Fukunaga, Kazuhiko Fujiwara, Kanehisa Yokoyama, Kentaro Fujimoto
-
Publication number: 20100016566Abstract: A method of synthesizing a cDNA chain using an insoluble carrier having on the surface thereof a polymer substance containing a first unit having a group derived from a phosphoric ester composing the hydrophilic portion of phospholipid, and a second unit having a group derived from carboxylic acid having an electron-attractive substituent bound to a carbonyl group, which includes immobilizing a polynucleotide for DNA elongation; bringing a solution containing an RNA fragment, nucleotide monomers, and a reverse transcriptase or an enzyme having polymerase activity into contact with the surface of the insoluble carrier; and allowing the polynucleotide for DNA elongation immobilized on the surface of the carrier to elongate using the RNA fragment contained in the solution as a template, to thereby form a single-strand cDNA.Type: ApplicationFiled: August 9, 2006Publication date: January 21, 2010Inventors: Kenji Kinoshita, Toru Yakabe, Kentaro Fujimoto, Kanehisa Yokoyama, Kazuhiko Fujiwara
-
Publication number: 20090137406Abstract: The present invention provides an RNA detection method detecting, from a reaction system containing a target sample, a target RNA chain originated from the target sample, using a surface having on the surface thereof a polymer substance which contains a first unit having a group derived from a phosphate ester composing the hydrophilic portion of a phospholipid and a second unit having a carboxylic acid derivative group composed of an electron-attractive substitutional group bound to a carbonyl group, while being provided with at least one reaction space, the reaction space having an immobilized nucleic acid primer immobilized therein.Type: ApplicationFiled: June 1, 2007Publication date: May 28, 2009Inventors: Kenji Kinoshita, Kanehisa Yokoyama, Kentaro Fujimoto, Toru Yakabe, Shin Saito, Kazuhiko Fujiwara
-
Publication number: 20090042190Abstract: A method of detecting a gene including immobilizing a primer for DNA elongation onto an insoluble carrier having on the surface thereof a polymer substance containing a first unit having a phosphorylcholine group and a second unit having a carboxylic acid-derived group having an electron-attractive substituent bound to a carbonyl group; annealing the template DNA fragments or RNA fragments with the primer for DNA elongation, so as to elongate the DNA primer while incorporating therein an enzyme, thereby allowing coloration of a chromogenic reagent by its enzymatic action; and judging whether the DNA fragments or RNA fragments of the gene presents or not, based on the degree of coloration.Type: ApplicationFiled: May 16, 2006Publication date: February 12, 2009Inventors: Kenji Kinoshita, Kazuhiko Fujiwara, Kanehisa Yokoyama, Kentaro Fujimoto, Toru Yakabe
-
Patent number: 3935193Abstract: Novel diacyl penicillins of the formula ##EQU1## wherein R is alkyl, cycloalkyl, aryl, aralkyl, phenoxyalkyl, heterocyclic carboxyl excepting isoxazole carboxyl derivatives, or ##SPC1##In which benzene ring A may optionally be substituted andB represents a protective group for the amino group, and X is a protective group for the carboxyl group, are produced by reacting a benzyl penicillin ester of the formula ##EQU2## wherein X is as defined above, with a chlorinating agent in the presence of tertiary organic base to obtain an imide chloride group-incorporated compound of the formula ##EQU3## and then reacting the compound of the last-named formula with carboxylate of the formulaR-COOM (IV)wherein M is a metal atom, and R is as defined above.Type: GrantFiled: December 29, 1970Date of Patent: January 27, 1976Assignee: Toyo Jozo Kabushiki KaishaInventors: Jinnosuke Abe, Tetsuo Watanabe, Teruo Take, Kentaro Fujimoto, Tadashiro Fujii, Kazuyoshi Nishiie