Abstract: A state estimation device includes an information acquisition unit acquiring at least one of (i) electrode acquisition information indicating an electromagnetic time series that is a time series of an electromagnetic quantity that is an electromagnetic force, field, or energy applied to an electrode from which a signal indicating a state of a heart of an estimation target is acquirable or (ii) environment information that is information on a time series of an environmental quantity that is an amount related to one or both of a state of motion of the estimation target and an environment in which the estimation target is present; and an estimation unit using at least one of the electrode acquisition information or the environment information to determine whether an electrode event, which is an abnormality in acquisition of a signal indicating the state of the heart of the estimation target by the electrode, has occurred.

Abstract: An interference image acquisition apparatus includes a light source, a beam splitter, a second reflection mirror, an imager, and a first reflection mirror. A cell is placed on one side of a transparent material, and the first reflection mirror is placed on the other side of the transparent material. In a two-beam interferometer, an optical path difference between an optical path length of a first light beam reflected by the first reflection mirror and an optical path length of a second light beam reflected by the second reflection mirror is set to a coherence length of light output from the light source or less. The imager acquires an interference image in a state in which the cell is placed at a position conjugate to an imaging plane in a first optical system between the imaging plane and the first reflection mirror.

Abstract: An evaluation method is a method for evaluating a cell mass containing a plurality of aggregated cells, and includes an imaging step of capturing an image of light obtained from the cell mass by irradiating the cell mass with light, an analysis step of setting a reference point for the cell mass included in image data obtained by the imaging step, setting sampling circles centered on the reference point, and determining a parameter for a state of the cell mass based on image data included in regions on the sampling circles, and an evaluation step of evaluating the cell mass based on the parameter.

Abstract: An object is to provide a non-red phosphorus type flame retardant composition for polyurethane foam that does not undergo dripping ignition and readily forms a carbonized layer when the polyurethane foam is burned and a flame-retarded polyurethane foam containing the flame retardant composition for polyurethane foam. As a solution, a flame retardant composition for polyurethane foam having high carbonization properties, the flame retardant composition for polyurethane foam containing a phosphorus compound represented by formula (1), is provided. (In formula, M is Mg, Al, Ca, Ti, or Zn, and m is 2, 3, or 4.

Abstract: In a health monitoring system analyzing urination of a user using a toilet, a transfer unit that immerses a film producing a color reaction for a composition to be detected in reserved water containing urine includes a clamping unit that clamps the film in an opening/closing part of an upper clamping member and a lower clamping member of which one ends are connected through a connection shaft, an upper drive unit that drives an upper rod to which the upper clamping member is connected in a longitudinal direction of the upper rod, a lower drive unit that drives a lower rod to which the lower clamping member is connected in a longitudinal direction of the lower rod, and a moving drive unit that drives a first moving rod connected to the upper clamping member and a second moving rod connected to the lower clamping member in longitudinal directions of the first and second moving rods.

Abstract: An evaluation method is a method for evaluating a cell mass containing a plurality of aggregated cells, and includes an imaging step of capturing an image of light obtained from the cell mass by irradiating the cell mass with light, an analysis step of setting a reference point for the cell mass included in image data obtained by the imaging step, setting sampling circles centered on the reference point, and determining a parameter for a state of the cell mass based on image data included in regions on the sampling circles, and an evaluation step of evaluating the cell mass based on the parameter.

Abstract: An interference image acquisition apparatus includes a light source, a beam splitter, a second reflection mirror, an imager, and a first reflection mirror. A cell is placed on one side of a transparent material, and the first reflection mirror is placed on the other side of the transparent material. In a two-beam interferometer, an optical path difference between an optical path length of a first light beam reflected by the first reflection mirror and an optical path length of a second light beam reflected by the second reflection mirror is set to a coherence length of light output from the light source or less. The imager acquires an interference image in a state in which the cell is placed at a position conjugate to an imaging plane in a first optical system between the imaging plane and the first reflection mirror.

Abstract: Provided is an observation target cover for interference observation using first light and second light having a coherent length longer than that of the first light so as to acquire an interference light image of an observation target by the first light while adjusting an optical path length difference based on an interference result of the second light, the observation target cover including: a transmission reflection portion that transmits the first light and reflects the second light; and a support portion for supporting the transmission reflection portion so that a placement surface on which the observation target is placed and the transmission reflection portion face each other with a predetermined gap therebetween.

Abstract: In a health monitoring system analyzing urination of a user using a toilet, a transfer unit that immerses a film producing a color reaction for a composition to be detected in reserved water containing urine includes a clamping unit that clamps the film in an opening/closing part of an upper clamping member and a lower clamping member of which one ends are connected through a connection shaft, an upper drive unit that drives an upper rod to which the upper clamping member is connected in a longitudinal direction of the upper rod, a lower drive unit that drives a lower rod to which the lower clamping member is connected in a longitudinal direction of the lower rod, and a moving drive unit that drives a first moving rod connected to the upper clamping member and a second moving rod connected to the lower clamping member in longitudinal directions of the first and second moving rods.

Abstract: An aggregated cell evaluation apparatus includes a laser light source, a speckle image acquisition unit, an SC calculation unit, an evaluation unit, and a memory unit. The speckle image acquisition unit acquires a two-dimensional speckle image by forward scattered light generated in aggregated cells by irradiation of the aggregated cells with laser light output from the laser light source. The SC calculation unit calculates a speckle contrast value Kn of a speckle image In at each time tn, determines a maximum value Kmax among the speckle contrast values K1 to KN, and normalizes the speckle contrast value Kn at each time tn by the maximum value Kmax to obtain a normalized speckle contrast value Kn?. The evaluation unit evaluates motion of the aggregated cells, based on the normalized speckle contrast value Kn? at each time tn.

Abstract: An aggregated cell evaluation apparatus includes a laser light source, a speckle image acquisition unit, an SC calculation unit, an evaluation unit, and a memory unit. The speckle image acquisition unit acquires a two-dimensional speckle image by forward scattered light generated in aggregated cells by irradiation of the aggregated cells with laser light output from the laser light source. The SC calculation unit calculates a speckle contrast value Kn of a speckle image In at each time tn, determines a maximum value Kmax among the speckle contrast values K1 to KN, and normalizes the speckle contrast value Kn at each time tn by the maximum value Kmax to obtain a normalized speckle contrast value Kn?. The evaluation unit evaluates motion of the aggregated cells, based on the normalized speckle contrast value Kn? at each time tn.

Abstract: The present invention relates to a cell evaluation method comprising evaluating a cell differentiation degree based on a cell thickness.

Abstract: Provided is an aqueous liquid preparation comprising: (a) any one of a prostaglandin derivative being represented by the following formula (I), a pharmaceutically acceptable salt thereof and a hydrate thereof; and (b) at least one polyol of glycerin, propylene glycol, dipropylene glycol and 1,3-butylene glycol.

Abstract: Provided is an aqueous liquid preparation comprising: (a) any one of a prostaglandin derivative being represented by the following formula (I), a pharmaceutically acceptable salt thereof and a hydrate thereof; and (b) at least one polyol of glycerin, propylene glycol, dipropylene glycol and 1,3-butylene glycol.

Abstract: A reception-signal adjusting unit adjusts a waveform of a digital reception signal so that amplitude is equally distributed on a positive side and a negative side. A digital filter unit adds a predetermined delay to an input signal by delay elements serially connected as many as taps, multiplies a delay-added signal from each of the delay elements by a corresponding tap coefficient, adds all signals after the multiplication. A CMA-tap-coefficient estimating unit estimates a tap coefficient using a CMA. A distortion in the waveform of the adjusted reception signal is compensated by repeating processes of the digital filter unit and the CMA-tap-coefficient estimating unit.