Abstract: Provided herein are 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity. These compounds are useful for the treatment of diseases associated with CCR3 activity, including but not limited to, atopic dermatitis, allergic rhinitis, rheumatoid arthritis, Grave's disease, HIV infection, Alzheimer's disease, atherosclerosis and other inflammatory and/or immunological disorders.

Abstract: A self-propelled crushing machine comprises a crushing device 20; a hydraulic drive system including a crushing device hydraulic motor 21 for driving the crushing device 20, a first hydraulic pump 62 for driving the crushing device hydraulic motor 21, and an engine 61 for driving the first hydraulic pump 62; a pressure sensor 151 for detecting a load condition of the crushing device 20; and a controller 84? for executing control to increase a revolution speed of the engine 61 in accordance with a detected signal from the pressure sensor 151. Accordingly, even when a heavy load is imposed on the crushing device, a reduction of crushing efficiency can be prevented.

Abstract: The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. In said formula, X represents O or S; R4 represents formulae (a), (b), (c), (d), (e), (f), (g), (h), (i) or (j), the other substituents are as defined in claim 1.

Abstract: This invention relates to chroman derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The chroman derivatives of the present invention have an excellent activity as BETA 3 antagonists and are useful for the prophylaxis and treatment of diseases associated with BETA 3 activity, in particular for the treatment of urological disorder or disease, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; and inflammatory disorders, such as asthma and COPD.

Abstract: A self-propelled crushing machine comprises a crushing device 20; a hydraulic drive system including a crushing device hydraulic motor 21 for driving the crushing device 20, a first hydraulic pump 62 for driving the crushing device hydraulic motor 21, and an engine 61 for driving the first hydraulic pump 62; a pressure sensor 151 for detecting a load condition of the crushing device 20; and a controller 84? for executing control to increase a revolution speed of the engine 61 in accordance with a detected signal from the pressure sensor 151. Accordingly, even when a heavy load is imposed on the crushing device, a reduction of crushing efficiency can be prevented.

Abstract: A series of driven rolls for separating blow-molded products from segments of flash material in a string of products formed in a synthetic resin continuous molding machine. A first pair of rolls receives a string of products joined by flashes as the products are removed from the dies of a blow-molding apparatus. At least one of the rolls in the first pair of rolls is driven at a first rotational speed. An intermediate pair of rolls receives the string of products and flashes from the first pair of rolls, and the intermediate rolls are driven at a speed faster than the first rotational speed to stretch the string of products and thereby separate the flashing segments from the products. A pair of last rolls is spaced by an interval from the pair of intermediate rolls. The interval between the intermediate rolls and the last rolls is adjusted such that the products and the flashes can be sorted by length.

Abstract: A fluid container made of thin, soft synthetic resin includes a substantially cube-shaped body with at least one longitudinal cutout portion in a corner portion of the body, a straw member coextensively disposed in the cutout portion and which has one end thereof in communication with the interior of the container body, and a fluid infusion nozzle protruding from the container, the fluid infusion nozzle being retractably connected to the container body for being retracted after fluid infusion through the nozzle. The straw member also includes a bellows formed in an intermediate portion thereof and a reinforcement wall which interconnects the straw with the container.

Abstract: A plastic beverage container is formed from a tubular blank and has a lower portion formed in a bottle-like shape and an upper portion which includes a gradually diametrically reduced bellows tube. The upper portion further comprises a mouth tube with a smaller diameter than the bellows tube with the upper portion of the mouth tube forming a small tube with a smaller diameter than the mouth tube. The upper portion of the small tube forms a fine tube with a smaller diameter than the small tube with a thin walled junction formed between the small tube and the mouth tube. The small tube is provided with a pair of outwardly extending twist vanes to permit the tube to be broken at the thin walled junction for consumption of the beverage.