Patents by Inventor Kenton L. Lohman

Kenton L. Lohman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10982274
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: April 20, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steven Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20190203263
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: January 16, 2019
    Publication date: July 4, 2019
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 10240192
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: March 26, 2019
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steven Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20160298175
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 13, 2016
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steven Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20150099672
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: October 20, 2014
    Publication date: April 9, 2015
    Inventors: JAN BERKA, YI-JU CHEN, JOHN H. LEAMON, STEVEN LEFKOWITZ, KENTON L. LOHMAN, VINOD B. MAKHIJANI, JONATHAN M. ROTHBERG, GARY J. SARKIS, MAITHREYAN SRINIVASAN, MICHAEL P. WEINER
  • Patent number: 8790876
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: July 29, 2014
    Assignee: 454 Life Sciences Corporation
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Patent number: 8765380
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: July 1, 2014
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyn Srinivasan, Michael P. Weiner
  • Publication number: 20140162885
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: September 25, 2013
    Publication date: June 12, 2014
    Applicant: 454 LIFE SCIENCES CORPORATION
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steven Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 8748102
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: June 10, 2014
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20130078638
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the heads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 28, 2013
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20120238475
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Application
    Filed: March 13, 2012
    Publication date: September 20, 2012
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Patent number: 8158359
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: April 17, 2012
    Assignee: 454 Lice Sciences Corporation
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Patent number: 8012690
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: September 6, 2011
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20110201526
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: February 23, 2011
    Publication date: August 18, 2011
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Johathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20110009275
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Application
    Filed: June 24, 2010
    Publication date: January 13, 2011
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Patent number: 7842457
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: November 30, 2010
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20090048124
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Application
    Filed: April 20, 2007
    Publication date: February 19, 2009
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Publication number: 20080132693
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 5, 2008
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 7323305
    Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: January 29, 2008
    Assignee: 454 Life Sciences Corporation
    Inventors: John H. Leamon, Kenton L. Lohman, Jonathan M. Rothberg, Michael P. Weiner
  • Patent number: 7244567
    Abstract: This invention relates to methods of sequencing DNA. More specifically, this invention relates to methods of sequencing both the sense and antisense strands of DNA through the use of blocked and unblocked sequencing primers. In brief, these methods include the steps of annealing an unblocked primer to a first strand of nucleic acid; annealing a second blocked primer to a second strand of nucleic acid; elongating the nucleic acid along the first strand with a polymerase; terminating the first sequencing primer; deblocking the second primer; and elongating the nucleic acid along the second strand.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: July 17, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Yi-Ju Chen, John H. Leamon, Kenton L. Lohman, Michael T. Ronan, Jonathan M. Rothberg, Maithreyan Srinivasan, Michael P. Weiner