Patents by Inventor Kenzie MacIsaac

Kenzie MacIsaac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combined use of anti PD-1 and anti M-CSF antibodies in the treatment of cancer
    Patent number: 11001628
    Abstract: The present application n relates to a pharmaceutical composition comprising a PD-1 antibody and an M-CSF antibody. The combination can be administered independently or separately, in a quantity which is therapeutically effective for the treatment of cancer.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: May 11, 2021
    Assignee: NOVARTIS AG
    Inventors: Marie-Louise Fjaellskog, John Scott Cameron, Zhu Cao, Daniela Cipolletta, Kenzie MacIsaac
  • COMBINATION THERAPIES
    Publication number: 20200277378
    Abstract: Combination therapies comprising PD-1 inhibitors and other therapeutic agents used to treat or prevent cancerous conditions and disorders as follow. Combination therapies of three agents which are a PD-1 inhibitor, a CXCR2 inhibitor and a CSF-1/1R binding agent for treating a pancreatic cancer or a colorectal cancer. Combination therapies of three agents which are a PD-1 inhibitor, a CXCR2 inhibitor and an inhibitor of either TIM-3, C-MET or A2aR for treating a pancreatic cancer or a colorectal cancer. Combination therapies of three agents which are a PD-1 inhibitor, a LAG-3 inhibitor and (i) an inhibitor of either TGF-beta, TIM-3, C-MET, IL-1b or MEK or (ii) a GITR agonist or (iii) an A2aR antagonist or (iv) a CSF-1/1R binding agent for treating a breast cancer. Combination therapies of two agents which are a PD-1 inhibitor and a CXCR2 inhibitor for treating a pancreatic cancer, a colorectal cancer, a lung cancer or a breast cancer.
    Type: Application
    Filed: November 16, 2018
    Publication date: September 3, 2020
    Inventors: Catherine Anne Sabatos-Peyton, Jennifer Marie Mataraza, Kenzie MacIsaac, Eunice Kwak, Jason Faris, Glenn Dranoff, Marion Wiesmann, Fiona Sharp, Adam Crystal, John Scott Cameron, Robert Martin Strieter, Lilli Petruzzelli, Shamsah Kazani, David Andrew Sandham, Neil John Press, Keith Hoffmaster
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20160130659
    Abstract: The instant invention relates to methods for the treatment of B-cell lymphomas and leukemia by administering a SYK inhibitor. In another embodiment, the invention relates to a method for treating a patient diagnosed with a B-cell lymphoma or leukemia, comprising administering a SYK inhibitor, wherein the B-cells of said patient to be treated are characterized by elevated expression levels of CD86.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 12, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Kenzie MacIsaac, Manfred Kraus, Peter Richard Strack, Kumiko Nagashima, John Michael Ellis