Patents by Inventor Kenzo Terashita

Kenzo Terashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting candidate alzheimer's disease drug
    Patent number: 8252543
    Abstract: The present invention provides a method for detecting or diagnosing in vitro Alzheimer's disease, or memory and/or cognitive disorders, using a human biological sample and the inactivation of STAT3 protein as an indication, and a method for screening for a therapeutic drug for Alzheimer's disease or memory and/or cognitive disorders, using the activation of STAT3 protein as an indication.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: August 28, 2012
    Assignees: Tomohiro Chiba, Marina Yamada, Kenzo Terashita, Tomo Nishimoto, Sadakazu Aiso, Masaaki Matsuoka
    Inventors: Tomohiro Chiba, Marina Yamada, Kenzo Terashita, Sadakazu Aiso, Masaaki Matsuoka
  • Therapeutic agents of colivelin for neurodegenerative diseases
    Patent number: 8076449
    Abstract: The present invention relates to a pharmaceutical composition for the treatment and/or prevention of a neurodegenerative disease, comprising the following polypeptide shown in any of (a) to (c): (a) a polypeptide comprising the amino acid sequence represented by Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1); (b) a polypeptide comprising an amino acid sequence having a deletion, substitution, insertion, and/or addition of one or several amino acids in the amino acid sequence consisting of Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1), and having an activity that inhibits neuronal cell death associated with neurodegenerative disease; and (c) a modified polypeptide from the polypeptide (a) or (b), or a pharmaceutically acceptable salt thereof, as an effective ingredient.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: December 13, 2011
    Assignees: Tomohiro Chiba, Massaaki Matsuoka, Kenzo Terashita, Sadakazu Also, Tomo Nishimoto
    Inventors: Tomohiro Chiba, Yoshiko Kita, Masaaki Matsuoka, Kenzo Terashita, Sadakazu Aiso, Ikuo Nishimoto, Tomo Nishimoto, legal representative
  • METHODS FOR TREATING MOTOR NEURON DISEASE
    Publication number: 20100279942
    Abstract: An object of the present invention is to provide an agent effective for the treatment and/or prevention of motor neuron disease such as amyotrophic lateral sclerosis (ALS). The present invention provides a therapeutic and/or preventive agent for motor neuron disease comprising the following oligopeptide shown in any of (a) to (c) or a pharmaceutically acceptable salt thereof as an active ingredient: (a) an oligopeptide consisting of the amino acid sequence represented by Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala (SEQ ID NO: 1); (b) an oligopeptide consisting of an amino acid sequence having a deletion, substitution, insertion, or addition of one or several amino acids in Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala (SEQ ID NO: 1), and having an activity that inhibits neuronal cell death caused by a mutant superoxide dismutase-1 gene; and (c) a modified oligopeptide from the oligopeptide (a) or (b).
    Type: Application
    Filed: April 7, 2010
    Publication date: November 4, 2010
    Inventors: TOMOHIRO CHIBA, YOSHIKO KITA, MASAAKI MATSUOKA, KENZO TERASHITA, SADAKAZU AISO, IKUO NISHIMOTO, TOMO NISHIMOTO
  • Therapeutic agent for motor neuron disease
    Publication number: 20090075900
    Abstract: An object of the present invention is to provide an agent effective for the treatment and/or prevention of motor neuron disease such as amyotrophic lateral sclerosis (ALS). The present invention provides a therapeutic and/or preventive agent for motor neuron disease comprising the following oligopeptide shown in any of (a) to (c) or a pharmaceutically acceptable salt thereof as an active ingredient: (a) an oligopeptide consisting of the amino acid sequence represented by Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala (SEQ ID NO: 1); (b) an oligopeptide consisting of an amino acid sequence having a deletion, substitution, insertion, or addition of one or several amino acids in Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala (SEQ ID NO: 1), and having an activity that inhibits neuronal cell death caused by a mutant superoxide dismutase-1 gene; and (c) a modified oligopeptide from the oligopeptide (a) or (b).
    Type: Application
    Filed: December 8, 2004
    Publication date: March 19, 2009
    Applicants: Sadakazu, NOEVIR CO., LTD.
    Inventors: Sadakazu Aiso, Masaaki Matsuoka, Tomohiro Chiba, Yoshiko Kita, Kenzo Terashita
  • Therapeutic Agent for Neurodegenerative Diseases
    Publication number: 20080227699
    Abstract: The present invention relates to a pharmaceutical composition for the treatment and/or prevention of a neurodegenerative disease, comprising the following polypeptide shown in any of (a) to (c): (a) a polypeptide comprising the amino acid sequence represented by Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1); (b) a polypeptide comprising an amino acid sequence having a deletion, substitution, insertion, and/or addition of one or several amino acids in the amino acid sequence consisting of Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1), and having an activity that inhibits neuronal cell death associated with neurodegenerative disease; and (c) a modified polypeptide from the polypeptide (a) or (b), or a pharmaceutically acceptable salt thereof, as an effective ingredient.
    Type: Application
    Filed: April 8, 2005
    Publication date: September 18, 2008
    Inventors: Tomohiro Chiba, Yoshiko Kita, Masaaki Matsuoka, Kenzo Terashita, Sadakazu Aiso, Ikuo Nishimoto, Tomo Nishimoto
  • Method for detecting Alzheimer's disease
    Publication number: 20080102055
    Abstract: The present invention provides a method for detecting or diagnosing in vitro Alzheimer's disease, or memory and/or cognitive disorders, using a human biological sample and the inactivation of STAT3 protein as an indication, and a method for screening for a therapeutic drug for Alzheimer's disease or memory and/or cognitive disorders, using the activation of STAT3 protein as an indication.
    Type: Application
    Filed: August 31, 2007
    Publication date: May 1, 2008
    Applicants: Tomohiro CHIBA, Marina YAMADA, Kenzo TERASHITA, Tomo NISHIMOTO, Sadakazu AISO, Masaaki MATSUOKA
    Inventors: Tomohiro Chiba, Marina Yamada, Kenzo Terashita, Sadakazu Aiso, Masaaki Matsuoka