Patents by Inventor Keping Xie

Keping Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of Angiogenesis by Mithramycin
    Publication number: 20080274121
    Abstract: We disclose a method of inhibiting angiogenesis in a mammal by administering by a subcutaneous or intraperitoneal route to a tissue in the mammal where angiogenesis is occurring a composition comprising mithramycin and a pharmaceutically-acceptable carrier. We have found a subcutaneous or intraperitoneal dose from about 10 ?g mithramycin per kg body weight per day to about 500 ?g mithramycin per kg body weight per day can be effective for inhibition of angiogenesis.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Inventors: James C. Yao, Keping Xie
  • Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
    Patent number: 7252976
    Abstract: The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis. Therefore, the invention is applied to ascertain the quantity of EPCs in a subject, and to diagnose and monitor angiogenesis, for example, in injured tissues and in cancer development and progression.
    Type: Grant
    Filed: July 11, 2003
    Date of Patent: August 7, 2007
    Assignee: Board of Regents the University of Texas System
    Inventors: Edward H. Lin, Xifeng Wu, Keping Xie
  • Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
    Publication number: 20040086915
    Abstract: The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis. Therefore, the invention is applied to ascertain the quantity of EPCs in a subject, and to diagnose and monitor angiogenesis, for example, in injured tissues and in cancer development and progression.
    Type: Application
    Filed: July 11, 2003
    Publication date: May 6, 2004
    Applicant: Board of Regents, The University of Texas System
    Inventors: Edward H. Lin, Xifeng Wu, Keping Xie