Patents by Inventor Keriann M. BACKUS

Keriann M. BACKUS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LYSINE REACTIVE PROBES AND USES THEREOF
    Publication number: 20210255193
    Abstract: Disclosed herein are methods and compounds for profiling a lysine reactive protein. Also described herein are methods, compounds, and compositions for identifying a small molecule fragment ligand that interacts with a reactive lysine residue.
    Type: Application
    Filed: December 31, 2020
    Publication date: August 19, 2021
    Inventors: Benjamin F. CRAVATT, Stephan M. HACKER, Keriann M. BACKUS
  • CYSTEINE REACTIVE PROBES AND USES THEREOF
    Publication number: 20200292555
    Abstract: Disclosed herein are methods, compositions, probes, polypeptides, assays, and kits for identifying a cysteine containing protein as a binding target for a small molecule fragment. Also disclosed herein are methods, compositions, and probes for mapping a biologically active cysteine site on a protein and screening a small molecule fragment for interaction with a cysteine containing protein.
    Type: Application
    Filed: June 2, 2020
    Publication date: September 17, 2020
    Inventors: Benjamin F. CRAVATT, Keriann M. BACKUS, Bruno E. CORREIA, Megan M. BLEWETT, John R. TEIJARO
  • Cysteine reactive probes and uses thereof
    Patent number: 10670605
    Abstract: Disclosed herein are methods, compositions, probes, polypeptides, assays, and kits for identifying a cysteine containing protein as a binding target for a small molecule fragment. Also disclosed herein are methods, compositions, and probes for mapping a biologically active cysteine site on a protein and screening a small molecule fragment for interaction with a cysteine containing protein.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: June 2, 2020
    Assignee: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Benjamin F. Cravatt, Keriann M. Backus, Bruno E. Correia, Megan M. Blewett, John R. Teijaro
  • LYSINE REACTIVE PROBES AND USES THEREOF
    Publication number: 20180372751
    Abstract: Disclosed herein are methods and compounds for profiling a lysine reactive protein. Also described herein are methods, compounds, and compositions for identifying a small molecule fragment ligand that interacts with a reactive lysine residue.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventors: Benjamin F. CRAVATT, Stephan M. HACKER, Keriann M. BACKUS
  • CYSTEINE REACTIVE PROBES AND USES THEREOF
    Publication number: 20170115303
    Abstract: Disclosed herein are methods, compositions, probes, polypeptides, assays, and kits for identifying a cysteine containing protein as a binding target for a small molecule fragment. Also disclosed herein are methods, compositions, and probes for mapping a biologically active cysteine site on a protein and screening a small molecule fragment for interaction with a cysteine containing protein.
    Type: Application
    Filed: October 21, 2016
    Publication date: April 27, 2017
    Inventors: Benjamin F. CRAVATT, Keriann M. BACKUS, Bruno E. CORREIA, Megan M. BLEWETT, John R. TEIJARO