Patents by Inventor Kerim Gattas-Asfura

Kerim Gattas-Asfura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dendritic and hyperbranched polymers for cellular encapsulation and functionalization
    Patent number: 9198872
    Abstract: A protective coating for covering a biological material, the protective coating having a plurality of interconnected layers covalently bonded to each other. The plurality of interconnected layers can include at least one hyperbranched polymeric material, and at least one dendrimer. A method of forming a protective coating for covering a biological material, the method can include depositing a plurality of interconnected layers, which are covalently bonded to each other. The plurality of interconnected layers can include at least one hyperbranched polymeric material, and at least one dendrimer.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: December 1, 2015
    Assignee: University of Miami
    Inventors: Cherie Stabler, Kerim Gattas-Asfura
  • Cross-linked alginate-polyalkylene glycol polymer coatings for encapsulation and methods of making the same
    Patent number: 8728520
    Abstract: A biocompatible capsule comprising a biological material encapsulated by a covalently stabilized coating and a method of making the same are disclosed. The biological material can be a material selected from the group consisting of cells, such as islets of Langerhans, pharmaceuticals, and biological agents. The coating can be formed by reacting an alginate-[polyalkylene glycol (PAG)-X1]n, and a multi-functional PAG-X2, to form covalent bonds, wherein n is an integer greater than 0, a first one of X1 and X2 is N3, and a second one of X1 and X2 is selected from the group consisting of: wherein R1=CH3, CH2CH3, CH(CH3)2, R2=N(CH3)2, OCH3, OH, CH3, H, F, Cl, Br or NO2, and R3=OCH3, CH3, H, F, Cl or NO2.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: May 20, 2014
    Assignee: University of Miami
    Inventors: Cherie Stabler, Kerim Gattas-Asfura, Kristina Finn, Camillo Ricordi, Hernan R Rengifo
  • DENDRITIC AND HYPERBRANCHED POLYMERS FOR CELLULAR ENCAPSULATION AND FUNCTIONALIZATION
    Publication number: 20120328673
    Abstract: A protective coating for covering a biological material, the protective coating having a plurality of interconnected layers covalently bonded to each other. The plurality of interconnected layers can include at least one hyperbranched polymeric material, and at least one dendrimer. A method of forming a protective coating for covering a biological material, the method can include depositing a plurality of interconnected layers, which are covalently bonded to each other. The plurality of interconnected layers can include at least one hyperbranched polymeric material, and at least one dendrimer.
    Type: Application
    Filed: June 25, 2012
    Publication date: December 27, 2012
    Applicant: UNIVERSITY OF MIAMI
    Inventors: Cherie STABLER, Kerim GATTAS-ASFURA
  • CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME
    Publication number: 20100143464
    Abstract: A biocompatible capsule comprising a biological material encapsulated by a covalently stabilized coating and a method of making the same are disclosed. The biological material can be a material selected from the group consisting of cells, such as islets of Langerhans, pharmaceuticals, and biological agents. The coating can be formed by reacting an alginate-[polyalkylene glycol (PAG)-X1]n, and a multi-functional PAG-X2, to form covalent bonds, wherein n is an integer greater than 0, a first one of X1 and X2 is N3, and a second one of X1 and X2 is selected from the group consisting of: wherein R1=CH3, CH2CH3, CH(CH3)2, R2=N(CH3)2, OCH3, OH, CH3, H, F, Cl, Br or NO2, and R3=OCH3, CH3, H, F, Cl or NO2.
    Type: Application
    Filed: December 8, 2009
    Publication date: June 10, 2010
    Inventors: Cherie Stabler, Kerim Gattas-Asfura, Kristina Finn, Camillo Ricordi, Hernan R. Rengifo