Patents by Inventor Kerry Leigh Spear

Kerry Leigh Spear has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polycyclic pyrazines as potassium ion channel modulators
    Patent number: 7642354
    Abstract: The present invention provides a genus of polycyclic pyrazines of formula (I): wherein A and B are independently substituted or unsubstituted 5- or 6- membered heterocycloalkyl, or substituted or unsubstituted 5- or 6- membered heteroaryl, W1 is W2is —CH?, —NH—, —N?, —S—, or —O—; Z1 is Z2 is —CH?, —NH—, —N?, —S—, or —O—; Y is a bond, —CH?N—NH—, —NH—CH2, or —NR5—; s and t are independently integers from 1 to 4; and the substituents R1, R2A, R2B and R3 are as defined in the specification for compounds of formula (I). The polycyclic pyrazine compounds are useful as modulators of potassium ion channels in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: January 5, 2010
    Assignee: Icagen, Inc.
    Inventors: Xiaodong Wang, Kerry Leigh Spear, Alan Bradley Fulp, Darrick Seconi, Takeshi Suzuki, Takahiro Ishii, Ayako Moritomo
  • Polycyclic pyrimidines as potassium ion channel modulators
    Patent number: 7560464
    Abstract: The present invention provides a genus of polycyclic pyrimidines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: July 14, 2009
    Assignee: Icagen, Inc.
    Inventors: Xiaodong Wang, Kerry Leigh Spear, Alan Bradley Fulp, Darrick Seconi, Takeshi Suzuki, Takahiro Ishii, Ayako Moritomo
  • Bis-benzimidazoles and related compounds as potassium channel modulators
    Patent number: 7482373
    Abstract: The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: January 27, 2009
    Assignee: Icagen, Inc.
    Inventors: Xiaodong Wang, Alan Bradley Fulp, Albert Michiel van Rhee, Kerry Leigh Spear
  • Polycyclic pyridines as potassium ion channel modulators
    Patent number: 7459457
    Abstract: The present invention provides a genus of polycyclic pyridines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: December 2, 2008
    Assignee: Icagen, Inc.
    Inventors: Xiaodong Wang, Kerry Leigh Spear, Alan Bradley Fulp, Darrick Seconi