Patents by Inventor Kerry M. Ervin

Kerry M. Ervin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for quantitating competitive binding of molecules to proteins utilizing fluorescence polarization
    Patent number: 6511815
    Abstract: The system comprises mixing a fluorescence-emitting compound that binds to the steroid hormone receptors in a solution containing the steroid hormone receptors. Then, measuring the fluorescence polarization of the solution. Subsequently, incubating the solution with at least one molecule that may compete with the compound for interaction with the steroid hormone receptors. Measuring the fluorescence polarization of the solution again. Finally, comparing the fluorescence polarization measurements to quantify any competitive interaction.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: January 28, 2003
    Assignee: PanVera LLC
    Inventors: Thomas J. Burke, Randall E. Bolger, Kerry M. Ervin, Robert G. Lowery, William J. Checovich
  • Processes for receptpor screening
    Publication number: 20020146741
    Abstract: A method is provided for measuring competitive binding activity of molecules to nuclear receptors comprising mixing a fluorescence-emitting compound that specifically binds to steroid hormone receptors in a solution wherein the fluorescence-emitting compound is in concentration below the dissociation constant and the steroid hormone receptors are at or above the dissociation constant using fluorescence polarization.
    Type: Application
    Filed: July 30, 2001
    Publication date: October 10, 2002
    Inventors: Cale M. Halbleib, Kerry M. Ervin, Mohammed S. Shekhani, Robert G. Lowery, William J. Checovich, Thomas J. Burke