Abstract: A system for applying a stamp to packs within a carton includes a conveyor system including a plurality of spring arms and a ceiling plate positioned above the spring arms. The system also includes a carton opening system positioned at a first station along the conveyer system, a pack stamping system positioned at a second station along the conveyer system, and a carton closing system positioned at a third station along the conveyor system; wherein the spring arms bias the cartons against the ceiling plate to position the packs at a predetermined distance form the carton opening system, pack stamping system and carton closing system. A method for applying a stamp to packs within a carton includes biasing the carton along a conveyor system, and positioning the packs within the carton at a predetermined location from operation stations based on the biasing.

Abstract: A system for applying a stamp to packs within a carton includes a conveyor drum system including a plurality of clamps and a floor plate positioned adjacent the clamps. The system further includes a carton opening system positioned at a first station along the conveyor drum system, a pack stamping system positioned at a second station along the conveyor drum system, and a carton closing system positioned at a third station along the conveyor drum system. The clamps are opened to receive at least one carton and the floor plate moves upward to position the packs at a predetermined operating distance and wherein the clamps are closed to hold the carton at the predetermined operating distance while the carton is rotated through the carton opening system, pack opening system and carton closing system.

Abstract: A system for applying a stamp to packs within a carton includes a conveyor system and a stamping system positioned along the conveyor system. The stamping system includes a stamp cartridge and a stamp applicator positioned adjacent the stamp cartridge. The cartridge dispenses stamps and the applicator applies the dispensed stamps to the packs. A method for applying a stamp to packs within a carton includes advancing at least one carton having a plurality of packs to a stamping station, dispensing stamps from a stamp cartridge positioned at the stamping station, and applying the dispensed stamps to the packs.

Abstract: A needle-less injector system having an ampule with an elongated hollow body. The elongated hollow body includes a nozzle and an aperture for receiving a plunger. The aperture extends from the second end of the body towards the first end and is in fluid communication with the nozzle. The ampule cooperates with a plunger that has a concave rib that extends about the perimeter of the plunger and towards the first end of the plunger. As the plunger moves through the aperture the concave rib sealingly engages the sidewalls of the aperture.

Abstract: The present invention provides novel isolated polynucleotides and small molecule target proteins encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target protein or any derivative, variant, mutant or fragment of that protein, polynucleotide or antibody are disclosed, as are methods in which the small molecule target protein, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Abstract: A needle-less injection system that uses an ampule with an elongated hollow body. The elongated hollow body including a nozzle and an aperture for accepting a plunger, the aperture for accepting a plunger extends from the second end towards the first end and is in fluid communication with the nozzle. The ampule cooperates with a generally cylindrical plunger. The plunger includes a first end and a second end, and a concave rib. The concave rib is extends about the perimeter of the plunger and extends towards the first end of the plunger.

Abstract: Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Abstract: The present invention provides novel isolated MEMX polynucleotides and polypeptides encoded by the MEMX polynucleotides. Also provided are the antibodies that immunospecifically bind to a MEMX polypeptide or any derivative, variant, mutant or fragment of the MEMX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the MEMX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

Abstract: The present invention is based upon methods of treating musculoskeletal or pro-inflammatory conditions and pathologies in mammals using. Methods of using the polynucleotide sequences and the the polypeptides encoded by such nucleic acid sequences, or variants, fragments and homologs thereof, are claimed in the invention. Similarly, methods of using OAX polynucleotide sequences and the OAX polypeptides encoded by such nucleic acid sequences, or variants, fragments and homologs thereof, alone or in combination, are also claimed in the invention. OAX collectively refers to any of six variant OAX sequences, variously designated OA1, OA2, OA3, and OA4.

Abstract: An optical networking unit includes a plurality of optical components mounted on a substrate composed of a material transparent to radiation in a frequency range. At least one of the optical components is secured to the substrate by a curable bonding material of a type curable in response to exposure to radiation in said frequency range. One optical component preferably comprises an optical fiber secured to an optical fiber holder holding the optical fiber and secured to the substrate. An active optical component is optically aligned with the optical fiber and is secured to an active optical component holder holding the active optical component and secured to the substrate.

Abstract: A passive optical network which is capable of full duplex digital transmission at high data rates and which also provides analog broadcast transmission is disclosed. A central station provides analog broadcast transmission at a first wavelength of light and full duplex digital transmission using second and third wavelengths of light. Optical networking units, electrically or wirelessly coupled to end users in the network, are optically coupled to the central station via passive optical network nodes. The optical networking units resolve the two broadcast streams from the central station employing compact optics configured on a transparent substrate and provide burst mode digital transmission up stream to the central station on a time division multiple access basis.

Abstract: A passive optical network which is capable of full duplex digital transmission at high data rates and which also provides analog broadcast transmission is disclosed. A central station provides analog broadcast transmission at a first wavelength of light and full duplex digital transmission using second and third wavelengths of light. Optical networking units, electrically or wirelessly coupled to end users in the network, are optically coupled to the central station via passive optical network nodes. The optical networking units resolve the two broadcast streams from the central station employing compact optics configured on a transparent substrate and provide burst mode digital transmission up stream to the central station on a time division multiple access basis.

Abstract: An optical networking unit includes a plurality of optical components mounted on a substrate composed of a material transparent to radiation in a frequency range. At least one of the optical components is secured to the substrate by a curable bonding material of a type curable in response to exposure to radiation in said frequency range. One optical component preferably comprises an optical fiber secured to an optical fiber holder holding the optical fiber and secured to the substrate. An active optical component is optically aligned with the optical fiber and is secured to an active optical component holder holding the active optical component and secured to the substrate.