Patents by Inventor Kersten Matthias Gericke
Kersten Matthias Gericke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230391761Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.Type: ApplicationFiled: August 11, 2023Publication date: December 7, 2023Inventors: Hartmut Beck, Stefanie Mesch, Alexandros Vakalopoulos, Nils Pfaff, Stefanie Zimmermann, Markus Follmann, Elisabeth Kersten, Guillaume Levilain, Kartrin Partikel, Andreas Peter Broehl, Stefan Heitmeier, Julia Dietze-Torres, Lutz Lehmann, Kersten Matthias Gericke, Frank Süßmeier, Lars Bärfacker, Alexander Hillisch, Adrian Tersteegen, Anja Buchmüller, Christoph Gerdes
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Publication number: 20200339567Abstract: The present application relates to novel substituted imidazopyridine amides of the formula (I), to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular, neurological and central nervous as well as metabolic disorders.Type: ApplicationFiled: October 18, 2018Publication date: October 29, 2020Applicants: Bayer Aktiengesellschaft, Bayer Pharma AktiengesellschaftInventors: Daniel MEIBOM, Jutta MEYER, Karl COLLINS, Nuria ORTEGA HERNANDEZ, Jan STAMPFUSS, Frank WUNDER, Till FREUDENBERGER, Thomas MONDRITZKI, Nina Alexandra SCHEERER, Kirsten LEINEWEBER, Jens SCHAMBERGER, Alexander STRAUB, Kersten Matthias GERICKE, Walter KROH, Mario LOBELL, Klaus MÜNTER
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Patent number: 10722501Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones of formula (I), to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.Type: GrantFiled: May 8, 2017Date of Patent: July 28, 2020Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFTInventors: Nicole Biber, Damian Brockschnieder, Kersten Matthias Gericke, Florian Kölling, Klemens Lustig, Jörg Meding, Heinrich Meier, Thomas Neubauer, Martina Schäfer, Andreas Timmermann, Dmitry Zubov, Carsten Terjung, Niels Lindner, Volker Badock, Dieter Moosmayer, Hideki Miyatake Ondozabal, Stephen Moore, Alexander Schulz
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Patent number: 10703742Abstract: The present application relates to a novel and improved process for preparing 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives of the formula (I) in which R1A and R1B are independently selected from the group consisting of hydrogen, fluorine, chlorine, methyl, monofluoromethyl, difluoromethyl, trifluoromethyl, ethyl, methoxy, difluoromethoxy and trifluoromethoxy, to novel precursors for preparation thereof, and to the preparation and use of the crystalline polymorph I of (5-(4-chlorophenyl)-2-({1-(3-chlorophenyl)-5-[(1S)-1-hydroxyethyl]-1H-1,2,4-triazol-3-yl}methyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one of the formula (I-A-1).Type: GrantFiled: May 2, 2017Date of Patent: July 7, 2020Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Heiko Schirmer, Philipp Rubenbauer, Hans-Christian Militzer, Marie-Pierre Collin-Kröpelin, Frank Süßmeier, Kersten Matthias Gericke, Thomas Neubauer, Chantal Fürstner
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Publication number: 20190160048Abstract: The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.Type: ApplicationFiled: May 8, 2017Publication date: May 30, 2019Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFTInventors: Nicole BIBER, Damian BROCKSCHNIEDER, Kersten Matthias GERICKE, Florian KÖLLING, Klemens LUSTIG, Jörg MEDING, Heinrich MEIER, Thomas NEUBAUER, Martina SCHÄFER, Andreas TIMMERMANN, Dmitry ZUBOV, Carsten TERJUNG, Niels LINDNER, Volker BADOCK, Dieter MOOSMAYER, Hideki MIYATAKE ONDOZABAL, Steven MOORE, Alexander SCHULZ
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Publication number: 20190144431Abstract: The present application relates to a novel and improved process for preparing 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives of the formula (I) in which R1A and R1B are independently selected from the group consisting of hydrogen, fluorine, chlorine, methyl, monofluoromethyl, difluoromethyl, trifluoromethyl, ethyl, methoxy, difluoromethoxy and trifluoromethoxy, to novel precursors for preparation thereof, and to the preparation and use of the crystalline polymorph I of (5-(4-chlorophenyl)-2-({1-(3-chlorophenyl)-5-[(1S)-1-hydroxyethyl]-1H-1,2,4-triazol-3-yl}methyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one of the formula (I-A-1).Type: ApplicationFiled: May 2, 2017Publication date: May 16, 2019Inventors: Heiko SCHIRMER, Philipp RUBENBAUER, Hans-Christian MILITZER, Marie-Pierre COLLIN-KRÖPELIN, Frank SÜßMEIER, Kersten Matthias GERICKE, Thomas NEUBAUER, Chantal FÜRSTNER
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Patent number: 10047096Abstract: The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.Type: GrantFiled: November 23, 2015Date of Patent: August 14, 2018Assignee: Bayer Pharma AktiengesellschaftInventors: Andreas Schall, Jürgen Klar, Mario Lobell, Hartmut Schirok, Joachim Telser, Steffen Müller, Dirk Brohm, Hans Briem, Hannah Jörißen, Joerg Keldenich, Michael Böttger, Georges Von Degenfeld, Thomas Schlange, Ulf Bömer, Niels Lindner, Hanna Eilken, Dmitrij Hristodorov, Pierre Wasnaire, Kersten Matthias Gericke, Lars Bärfacker
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Publication number: 20170253602Abstract: The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.Type: ApplicationFiled: November 23, 2015Publication date: September 7, 2017Applicant: Bayer Pharma AktiengesellschaftInventors: Andreas SCHALL, Jürgen KLAR, Mario LOBELL, Hartmut SCHIROK, Joachim TELSER, Steffen MÜLLER, Dirk BROHM, Hans BRIEM, Hannah JÖRIßEN, Joerg KELDENICH (deceased), Michael BÖTTGER, Georges DEGENFELD VON, Thomas SCHLANGE, Ulf BÖMER, Niels LINDNER, Hanna EILKEN, Dmitrij HRISTODOROV, Pierre WASNAIRE, Kersten Matthias GERICKE, Lars BÄRFACKER
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Patent number: 9493472Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.Type: GrantFiled: May 30, 2014Date of Patent: November 15, 2016Assignee: Bayer Pharma AktiengesellschaftInventors: Swen Allerheiligen, Anja Buchmüller, Karen Engel, Christoph Gerdes, Kersten Matthias Gericke, Michael Gerisch, Stefan Heitmeier, Alexander Hillisch, Tom Kinzel, Philip Lienau, Bernd Riedl, Susanne Röhrig, Martina Victoria Schmidt, Julia Strassburger, Adrian Tersteegen
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Publication number: 20160137647Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.Type: ApplicationFiled: May 30, 2014Publication date: May 19, 2016Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
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Publication number: 20160108039Abstract: The invention relates to substituted triazolopyridines and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.Type: ApplicationFiled: June 2, 2014Publication date: April 21, 2016Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
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Publication number: 20160108027Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.Type: ApplicationFiled: May 30, 2014Publication date: April 21, 2016Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
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Publication number: 20150183773Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumour disorders.Type: ApplicationFiled: March 10, 2015Publication date: July 2, 2015Inventors: Mario JESKE, Dirk HEIMBACH, Susanne RÖHRIG, Yolanda CANCHO GRANDE, Dirk SCHNEIDER, Ulrich RESTER, Eckhard BENDER, Mark MEININGHAUS, Katja ZIMMERMANN, Dmitry ZUBOV, Anja BUCHMÜLLER, Georges VON DEGENFELD, Christoph GERDES, Michael GERISCH, Mark Jean GNOTH, Kersten Matthias GERICKE
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Patent number: 8987248Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.Type: GrantFiled: March 12, 2010Date of Patent: March 24, 2015Assignee: Bayer Intellectual Property GmbHInventors: Mario Jeske, Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Kersten Matthias Gericke
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Patent number: 8575357Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.Type: GrantFiled: February 17, 2012Date of Patent: November 5, 2013Assignee: AiCuris GmbH & Co. KGInventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
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Publication number: 20130252948Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases and tumour diseases.Type: ApplicationFiled: May 14, 2013Publication date: September 26, 2013Applicant: BAYER INTELLECTUAL PROPERTY GmbHInventors: Dirk HEIMBACH, Susanne RÖHRIG, Yolanda CANCHO GRANDE, Eckhard BENDER, Katfa ZIMMERMANN, Anja BUCHMÜLLER, Christoph GERDES, Mark Jean GNOTH, Kersten Matthias GERICKE, Mario JESKE
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Patent number: 8440657Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases and tumour diseases.Type: GrantFiled: May 18, 2010Date of Patent: May 14, 2013Assignee: Bayer Intellectual Property GmbHInventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
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Publication number: 20130045999Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.Type: ApplicationFiled: February 17, 2012Publication date: February 21, 2013Applicant: AiCuris GmbH & Co. KGInventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
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Publication number: 20120220563Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.Type: ApplicationFiled: May 19, 2010Publication date: August 30, 2012Applicant: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
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Publication number: 20120214788Abstract: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumour diseases.Type: ApplicationFiled: February 20, 2012Publication date: August 23, 2012Applicant: Bayer Pharma AktiengesellschaftInventors: Dirk Heimbach, Susanne Röhrig, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Yolanda Cancho Grande, Mario Jeske, Kersten Matthias Gericke