Patents by Inventor Kerstin EMMRICH

Kerstin EMMRICH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated von Willebrand factor
    Patent number: 10808023
    Abstract: The present invention provides a modified polypeptide which binds Factor VIII. The modified polypeptide comprises a sequence as shown in SEQ ID NO:3 in which the sequence comprises at least one modification at a position selected from the group consisting of L18, V42, K149, N248, S279, V320, T325, Q395 and K418 such that the modified polypeptide binds to Factor VIII with an off rate lower than a reference polypeptide comprising an unmodified SEQ ID NO:3.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: October 20, 2020
    Assignee: CSL BEHRING LENGNAU AG
    Inventors: Arna Andrews, Con Panousis, Kerstin Emmrich, Michael Wilson, Steve Dower, Matthew Hardy, Dallas Hartman
  • Mutated truncated von Willebrand Factor
    Patent number: 10806774
    Abstract: The present invention provides a modified polypeptide which binds Factor VIII. The polypeptide comprises truncated von Willebrand Factor (VWF) which comprises a sequence as shown in SEQ ID NO:3 or a fragment thereof or a sequence 90% identical thereto, wherein the truncated VWF comprises at least one modification in comparison to SEQ ID NO: 3 in at least one position selected from the group consisting of SI, S3, LI 8, V42, S43, K149, N248, S279, V320, T325, Q395 and K418.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: October 20, 2020
    Assignee: CSL BEHRING LENGNAU AG
    Inventors: Arna Andrews, Con Panousis, Kerstin Emmrich, Michael Wilson, Steve Dower, Matthew Hardy, Dallas Hartman
  • MUTATED VON WILLEBRAND FACTOR
    Publication number: 20190016784
    Abstract: The present invention provides a modified polypeptide which binds Factor VIII. The modified polypeptide comprises a sequence as shown in SEQ ID NO:3 in which the sequence comprises at least one modification at a position selected from the group consisting of L18, V42, K149, N248, S279, V320, T325, Q395 and K418 such that the modified polypeptide binds to Factor VIII with an off rate lower than a reference polypeptide comprising an unmodified SEQ ID NO:3.
    Type: Application
    Filed: January 6, 2017
    Publication date: January 17, 2019
    Inventors: Arna ANDREWS, Con PANOUSIS, Kerstin EMMRICH, Michael WILSON, Steve DOWER, Matthew HARDY, Dallas HARTMAN
  • MUTATED TRUNCATED VON WILLEBRAND FACTOR
    Publication number: 20190015483
    Abstract: The present invention provides a modified polypeptide which binds Factor VIII. The polypeptide comprises truncated von Willebrand Factor (VWF) which comprises a sequence as shown in SEQ ID NO:3 or a fragment thereof or a sequence 90% identical thereto, wherein the truncated VWF comprises at least one modification in comparison to SEQ ID NO: 3 in at least one position selected from the group consisting of SI, S3, LI 8, V42, S43, K149, N248, S279, V320, T325, Q395 and K418.
    Type: Application
    Filed: January 6, 2017
    Publication date: January 17, 2019
    Applicant: CSL BEHRING RECOMBINANT FACILITY AG
    Inventors: Arna ANDREWS, Con PANOUSIS, Kerstin EMMRICH, Michael WILSON, Steve DOWER, Matthew HARDY, Dallas HARTMAN