Abstract: The present invention relates to a reconfigurable bioprocessing system (80) operable to perform a predetermined set of bioprocessing operations therein. The reconfigurable bioprocessing system (80) comprises a base unit (60) comprising a plurality of valve actuators (102). At least one of the plurality of valve actuators (102) is operable to releasably engage with at least part of a pinch valve cassette (103, 203) to control fluid flow through the pinch valve cassette (103, 203). At least part of the pinch valve cassette (103, 203) is removably attachable to the base unit (60) and the pinch valve cassette (103, 203) is provided adjacent to said plurality of valve actuators (102).

Abstract: The present invention relates to a cuffing insert for turning in heat resistant superalloys and stainless steels comprising a very fine grained hard substrate and a coating. The substrate comprises WC from about 5 to about 8 wt % Co and from about 0.3 to about 1.5 wt % Cr. In addition to that ppm levels of Ti and Ta are present. The ratio of Me/Co=(at-% Ti+ at-% Nb+ at-% Ta)/at-% Co is lower than or equal to about 0.014?(CW_Cr)*0.008 and higher than about 0.0005. The average sintered WC-grain size is from about 0.5 to about 0.95 ?m and CW_Cr from about 0.75 to about 0.95. The cemented carbide body is coated with a PVD TixAl1-xN-coating with an average composition of x being greater than about 0.4 but less than about 0.9, present as a single or multilayer coating with a total thickness of from about 1 to about 6 ?m.

Abstract: The present invention relates to a cuffing insert for turning in heat resistant superalloys and stainless steels comprising a very fine grained hard substrate and a coating. The substrate comprises WC from about 5 to about 8 wt % Co and from about 0.3 to about 1.5 wt % Cr. In addition to that ppm levels of Ti and Ta are present. The ratio of Me/Co=(at-% Ti+ at-% Nb+ at-% Ta)/at-% Co is lower than or equal to about 0.014?(CW_Cr)*0.008 and higher than about 0.0005. The average sintered WC-grain size is from about 0.5 to about 0.95 ?m and CW_Cr from about 0.75 to about 0.95. The cemented carbide body is coated with a PVD TixAl1-xN-coating with an average composition of x being greater than about 0.4 but less than about 0.9, present as a single or multilayer coating with a total thickness of from about 1 to about 6 ?m.