Patents by Inventor Kerstin Nolkrantz

Kerstin Nolkrantz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8268555
    Abstract: Disclosed is a method for sequential delivery of agents to and/or into a cell structure, wherein an electrolyte-filled tube is provided together with a counter electrode, said tube is connected to a voltage or current generator, at least two agents are introduced in a discrete mode into the electrolyte solution contained in the tube, which is placed close to the cell structure, one agent at the time being transported through the tube to and/or into said cell structure in which a pore has been formed by application of an electric field focused on the cell structure, resulting in electroporation of the cell structure. Also different applications of the method is disclosed, e.g. us of the method in order to transfer cell-impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: September 18, 2012
    Assignee: Cellectricon AB
    Inventors: Owe Orwar, Mattias Karlsson, Cecilia Farre, Kerstin Nolkrantz
  • Publication number: 20100159439
    Abstract: Disclosed is a method for sequential delivery of agents to and/or into a cell structure, wherein an electrolyte-filled tube is provided together with a counter electrode, said tube is connected to a voltage or current generator, at least two agents are introduced in a discrete mode into the electrolyte solution contained in the tube, which is placed close to the cell structure, one agent at the time being transported through the tube to and/or into said cell structure in which a pore has been formed by application of an electric field focused on the cell structure, resulting in electroporation of the cell structure. Also different applications of the method is disclosed, e.g. us of the method in order to transfer cell-impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure.
    Type: Application
    Filed: January 21, 2009
    Publication date: June 24, 2010
    Applicant: Cellectricon AB
    Inventors: Owe Orwar, Mattias Karlsson, Cecilia Farre, Kerstin Nolkrantz
  • Publication number: 20070288186
    Abstract: Method of product evaluation comprising the steps of applying at least one substance to a surface of an artificial substrate to form a substance-coated surface, wherein the substrate surface demonstrates at least one physical property selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 0 mJ/m2 to about 15 mJ/m2, a zeta-potential at a pH of about 5.0 of from about ?30 mV to about 30 mV, and combinations thereof, and performing at least one analysis of the substance-coated surface.
    Type: Application
    Filed: February 5, 2007
    Publication date: December 13, 2007
    Inventors: Saswati Datta, William Belcher, Sandra Murawski, Mannie Clapp, Steven Page, Magda El-Nokaly, Richard Tweddell, Sohini Paldey, Louis Wong, Ronald Warner, Kerstin Nolkrantz, Chitra Laxmanan, Brian Ranade, Jianjun Li, Randall Marsh, Maria Sanchez Pena
  • Publication number: 20050026283
    Abstract: Disclosed is a method for parallel delivery of agents to and/or into a cell structure, wherein at least two electrolyte-filled tubes are provided together with a counter electrode, the tubes being connected to a voltage or current generator, said agents being introduced into the electrolyte solution contained in the tubes, which are placed close to the cell structure, whereupon the agents are transported through the tubes to said cell structure and into the said structure through pores which have been formed by application of an electric field focused on the cell structure, resulting in electroporation of the cell structure. Also different applications of the method is disclosed, e.g. use of the method in order to transfer cell-impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure.
    Type: Application
    Filed: November 27, 2002
    Publication date: February 3, 2005
    Inventors: Owe Ormar, Mattias Karlsson, Kerstin Nolkrantz, Cecilia Farre
  • Publication number: 20050019921
    Abstract: Disclosed is a method for sequential delivery of agents to and/or into a cell structure, wherein an electrolyte-filled tube is provided together with a counter electrode, said tube is connected to a voltage or current generator, at least two agents are introduced in a discrete mode into the electrolyte solution contained in the tube, which is placed close to the cell structure, one agent at the time being transported through the tube to and/or into said cell structure in which a pore has been formed by application of an electric field focused on the cell structure, resulting in electroporation of the cell structure. Also different applications of the method is disclosed, e.g. us of the method in order to transfer cell-impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure.
    Type: Application
    Filed: November 27, 2002
    Publication date: January 27, 2005
    Inventors: Owe Orwar, Mattias Karlsson, Kerstin Nolkrantz, Cecilia Farre