Patents by Inventor Kerstin Reimers

Kerstin Reimers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9222074
    Abstract: The invention provides a process for producing a three-dimensional tissue by cultivating eucaryotic cells by introducing the cells into a matrix and cultivating the cells within the matrix in a cell culture medium within a cell culture vessel under controlled dissolved oxygen conditions of the cell culture medium. The matrix contains a support containing an optical oxygen sensor, which is an oxygen-sensitive dye, which upon irradiation with an excitation wavelength changes its emission characteristics in dependence on the dissolved oxygen concentration in the surrounding medium, including a dye phosphorescing upon irradiation of an excitation wavelength, which phosphorescence is quenched by dissolved oxygen.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: December 29, 2015
    Assignees: Medizinische Hochschule Hannover, Biomimetics Technologies, Inc.
    Inventors: Meir Israelowitz, Birgit Weyand, Peter Vogt, Kerstin Reimers, Herbert von Schroeder, Christoph Gille, Elmar Schmaelzlin
  • Patent number: 9066937
    Abstract: Epidermal lipoxygenase obtained from axolotl is utilized in pharmaceutical or cosmetic compositions. The compositions have use in wound healing, bone healing or conditioning of injured tissue, e.g. in wound dressings.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: June 30, 2015
    Assignee: Medizinische Hochschule Hannover
    Inventors: Peter Vogt, Bjoern Menger, Kerstin Reimers-Fadhlaoui
  • Patent number: 8696762
    Abstract: The present invention provides the use of spider silk threads for the production of tissue implants for medical use. A scaffolding matrix is provided for implantation, which matrix is comprised of spider silk thread and/or segments of spider silk threads which are cross-linked. The cross-linked spider silk thread segments essentially maintain a three-dimensional shape into which it is formed by pressing between molds. The three-dimensional shape obtainable by molding sufficiently stable to be used as an implant or for colonizing by mammalian cells while essentially maintaining the three-dimensional shape. In a further embodiment, the scaffolding matrix of cross-linked spider silk segments is at least partially covered by cells autologous or heterologous to the implant recipient. The matrix colonized with cells is obtainable by in vitro cultivation of isolated cells in suspension with the scaffolding matrix.
    Type: Grant
    Filed: December 11, 2006
    Date of Patent: April 15, 2014
    Assignee: Medizinische Hochschule Hannover
    Inventors: Peter Vogt, Christina Allmeling, Kerstin Reimers
  • Patent number: 8409227
    Abstract: The invention relates to a biocompatible neural implant for bridging interruptions or defects in nerves resulting from injuries sustained in an accident or following surgery. Inventive neural implants comprise fibers made from natural or synthetic spider silk and allow interrupted nerves to regenerate across defects such that functional nerve conduction is made possible within a short period of time.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: April 2, 2013
    Assignee: Medizinische Hochschule Hannover
    Inventors: Peter Vogt, Christina Allmeling, Kerstin Reimers
  • Publication number: 20120148657
    Abstract: In general, the present invention relates to epidermal lipoxygenase obtained from axolotl and pharmaceutical compositions containing the same. In particular, in a first aspect the present invention relates to pharmaceutical compositions containing lipoxygenase obtained from axolotl or functional homologues thereof having a lipoxygenase activity, in particular for use in wound healing, bone healing or conditioning of injured tissue, e.g. in wound dressings. In a further aspect, the present inventions relates to cosmetical compositions containing said lipoxygenase. Finally, the present invention provides methods for identifying modulators of wound healing, scarring, etc. comprising the step of determining compounds able to alterate the lipoxygenase enzyme activity.
    Type: Application
    Filed: May 28, 2010
    Publication date: June 14, 2012
    Inventors: Kerstin Reimers-Fadhlaoui, Peter Vogt, Menger Björn
  • Publication number: 20100228359
    Abstract: The present invention provides the use of spider silk threads for the production of tissue implants for medical use. A scaffolding matrix is provided for implantation, which matrix is comprised of spider silk thread and/or segments of spider silk threads which are cross-linked. The cross-linked spider silk thread segments essentially maintain a three-dimensional shape into which it is formed by pressing between moulds. The three-dimensional shape obtainable by moulding is sufficiently stable to be used as an implant or for colonizing by mammalian cells while essentially maintaining the three-dimensional shape. In a further embodiment, the scaffolding matrix of cross-linked spider silk segments is at least partially covered by cells autologous or heterologous to the implant recipient. The matrix colonized with cells is obtainable by in vitro cultivation of isolated cells in suspension with the scaffolding matrix.
    Type: Application
    Filed: December 11, 2006
    Publication date: September 9, 2010
    Applicant: MEDIZINISCHE HOCHSCHULE HANNOVER
    Inventors: Peter Vogt, Christina Allmeling, Kerstin Reimers
  • Publication number: 20080281420
    Abstract: The invention relates to a biocompatible neural implant for bridging interruptions or defects in nerves resulting from injuries sustained in an accident or following surgery. Inventive neural implants comprise fibers made from natural or synthetic spider silk and allow interrupted nerves to regenerate across defects such that functional nerve conduction is made possible within a short period of time.
    Type: Application
    Filed: September 6, 2006
    Publication date: November 13, 2008
    Inventors: Peter Vogt, Christina Allmeling, Kerstin Reimers