Patents by Inventor Kervin Smith

Kervin Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kojic acid polymers
    Patent number: 10543162
    Abstract: A controlled release system for kojic acid having improved stability has been identified. To minimize degradation, kojic acid was incorporated into a hydrolytically degradable polymer (e.g., a polycarbonate-ester)). By synthesizing polymer precursors containing kojic acid-linker-kojic acid chemical structures, versatile monomers were developed that can be used to modulate polymer properties. Additionally the synthetic method lends itself to the development of other polymer systems. Polymers having one or more groups that will yield kojic acid upon degradation of the polymer backbone, as well as methods of use thereof are described.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: January 28, 2020
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Kathryn Uhrich, Kervin Smith, Jonathan Faig
  • Process and intermediates for preparing poly(anhydride-esters)
    Patent number: 10023521
    Abstract: Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a solvent, to provide a diacid of formula (II), wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: July 17, 2018
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Kathryn E. Uhrich, Jonathan J. Faig, Kervin Smith
  • Kojic Acid Polymers
    Publication number: 20180116945
    Abstract: A controlled release system for kojic acid having improved stability has been identified. To minimize degradation, kojic acid was incorporated into a hydrolytically degradable polymer (e.g., a polycarbonate-ester)). By synthesizing polymer precursors containing kojic acid-linker-kojic acid chemical structures, versatile monomers were developed that can be used to modulate polymer properties. Additionally the synthetic method lends itself to the development of other polymer systems. Polymers having one or more groups that will yield kojic acid upon degradation of the polymer backbone, as well as methods of use thereof are described.
    Type: Application
    Filed: April 11, 2016
    Publication date: May 3, 2018
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Kathryn Uhrich, Kervin Smith, Jonathan Faig
  • PROCESS AND INTERMEDIATES FOR PREPARING POLY(ANHYDRIDE-ESTERS)
    Publication number: 20170121267
    Abstract: Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a solvent, to provide a diacid of formula (II), wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
    Type: Application
    Filed: June 10, 2015
    Publication date: May 4, 2017
    Applicant: Rutgers, the State University of New Jersey
    Inventors: Kathryn E. Uhrich, Jonathan J. Faig, Kervin Smith