Abstract: Disclosed is a method of quantitatively evaluating structural disturbance characteristics of present in-situ geo-stress in deep shale gas reservoirs, including: measuring geomechanics key parameters of key wells in different tectonic zones within a study area; performing interpretations of single-well profile rock mechanics and continuity of the in-situ geo-stress in magnitude and direction; establishing a geological model; performing anisotropic sequential Gaussian stochastic simulation to obtain three-dimensional (3D) heterogeneous rock mechanics parameter field distribution; performing prediction of distribution of geo-stress states in the study area, and calculating a stress structural index and stress disturbance factor of the target layer and a rotation degree of a maximum horizontal principal stress; and performing quantitative evaluation on an in-situ geo-stress structural disturbance and mapping.