Patents by Inventor Keshava Murthy

Keshava Murthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amorphous ziprasidone hydrochloride (5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1, 3-dihydro-2H-indol-2-one hydrochloride) and processes to produce the same
    Publication number: 20050256139
    Abstract: The present invention relates to a new and useful amorphous form of ziprasidone hydrochloride (5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride) and preparations thereof.
    Type: Application
    Filed: July 7, 2004
    Publication date: November 17, 2005
    Inventors: Carlos Zetina-Rocha, Allan Rey, Matthew Buck, Lotfi Derdour, Stephen Horne, Keshava Murthy
  • Methods of making ureas and guanidines including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin and bunazosin (exemplary of 2-substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor
    Patent number: 6080860
    Abstract: Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: June 27, 2000
    Assignee: Brantford Chemicalss Inc.
    Inventors: Khashayar Karimian, Keshava Murthy, Darren Hall
  • Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
    Patent number: 5872258
    Abstract: A process for making Fluconazole is provided comprising carrying out the following scheme of reaction: ##STR1##
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: February 16, 1999
    Assignee: Brantford Chemicals Inc.
    Inventors: Derrick L. J. Clive, Keshava Murthy, Gamini Weeratunga, Derek John Norris, Stephen Horne
  • Methods of making ureas and guanidines, including terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin, and bunazosin (exemplary of 2-substituted quinazoline compounds), and meobentine, and bethanidine and intermediates thereof
    Patent number: 5686612
    Abstract: Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: November 11, 1997
    Assignee: Brantford Chemicals Inc.
    Inventors: Khashayar Karimian, Keshava Murthy, Darren Hall
  • Methods of making ureas and guanidines, including, terazosin, prazosin, doxazosin, tiodazosin, trimazosin, quinazosin, and bunazosin (exemplary of 2- substituted quinazoline compounds), and meobentine, and bethanidine and intermediates therefor
    Patent number: 5675006
    Abstract: Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted Quinazolines), Meobentine and Bethanidine and novel intermediates suitable for use in such methods of synthesis are taught.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: October 7, 1997
    Assignee: Brantford Chemicals Inc.
    Inventors: Khashayar Karimian, Keshava Murthy, Darren Hall
  • Process for the production of an improved form of form 1 ranitidine
    Patent number: 5670671
    Abstract: Process for the production of an improved form of Form 1 Ranitidine Hydrochloride having improved filtration and drying characteristics, said process comprising in a substantially anhydrous hydroxylic solvent, comprising at least one alkanol solvent having 3-4 carbon atoms, adding anhydrous hydrogen chloride gas to Ranitidine free base wherein said substantially anhydrous hydroxylic solvent has the characteristics that it solubilizes the Ranitidine free base and hydrogen chloride gas, and subsequently recovering the improved form of Form 1 Ranitidine Hydrochloride.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: September 23, 1997
    Assignee: Brantford Chemicals Inc.
    Inventor: Keshava Murthy
  • Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
    Patent number: 5633386
    Abstract: A process for making Fluconazole is provided comprising carrying out the following scheme of reaction: ##STR1##
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 27, 1997
    Assignee: ACIC (Canada) Inc.
    Inventors: Keshava Murthy, Gamini Weeratunga, Derek J. Norris, Stephen Horne, Derrick L. J. Clive
  • Process for preparing halogenated 2,3-O-cyclocytidine derivatives
    Patent number: 5596093
    Abstract: A process from preparing 5-halogenated 2,3-O-cyclocytidine derivatives comprising reacting 2,3-O-cyclocytidine with a halogenating reagent, preferably N-bromosuccinimide, in the presence of an acid such as acetic or trifluoroacetic.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 21, 1997
    Assignee: ACIC (Canada) Inc.
    Inventors: Bruno K. Radatus, Khashayar Karimian, Anand Daljeet, Keshava Murthy
  • Method for the manufacture of benzothiazepine
    Patent number: 5559229
    Abstract: A process for the manufacture of Diltiazem or deacetyl-Diltiazem, which comprises the use of MIBK as solvent and NaOH as base.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: September 24, 1996
    Assignee: ACIC (Canada) Inc.
    Inventors: Keshava Murthy, Gamini Weeratunga, Burchat Andrew
  • 5-halo-2,3'-O-cyclocytidines
    Patent number: 5527782
    Abstract: A 5'-halo-2,3'-O-cyclocytidine of Formula I: ##STR1## wherein: X is a bromide, chloride, or iodide;Y is halide, sulfate, acetate, tosyl, mesyl, benzoate, and phosphate;R.sup.1 is hydrogen; andR.sup.2 is a hydroxy protecting group.Pharmaceutical compositions containing the above compounds exhibit antineoplastic activity.
    Type: Grant
    Filed: February 2, 1994
    Date of Patent: June 18, 1996
    Assignee: ACIC (Canada) Inc.
    Inventors: Bruno K. Radatus, Khashayar Karimian, Anand Daljeet, Keshava Murthy
  • Form of form 1 Ranitidine
    Patent number: 5523423
    Abstract: Process for the production of an improved form of Form 1 Ranitidine Hydrochloride having improved filtration and drying characteristics, said process comprising in a substantially anhydrous hydroxylic solvent, comprising at least one alkanol solvent having 3-4 carbon atoms, adding anhydrous hydrogen chloride gas to Ranitidine free base wherein said substantially anhydrous hydroxylic solvent has the characteristics that it solubilizes the Ranitidine free base and hydrogen chloride gas, and subsequently recovering the improved form of Form 1 Ranitidine Hydrochloride.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: June 4, 1996
    Assignee: ACIC (Canada) Inc.
    Inventors: Keshava Murthy, Bruno K. Radatus, Kanwarpal S. Swidhu
  • Methods for the manufacture of fluconazole
    Patent number: 5508423
    Abstract: A process for making Fluconazole comprising the steps of: ##STR1##
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 16, 1996
    Assignee: ACIC (Canada) Inc.
    Inventors: Keshava Murthy, Gamini Weeratunga, Derek J. Norris, Bruno K. Radatus