Patents by Inventor Keshava Rao Rapole

Keshava Rao Rapole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Convenient process of manufacture for difluoromethylornithine and related compounds
    Patent number: 7345196
    Abstract: A process for the manufacture of ?-Difluoromethylornithine, analogs and derivatives is described from ornithine hydrochloride or from N?-phthaloyl ornithine hydrochloride, conversion to an alkyl ester, conversion to solid derivatives through the formation of Schiff bases, subsequent halomethylation using suitable bases and hydrolysis.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: March 18, 2008
    Assignee: Sabinsa Corporation
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Keshava Rao Rapole, Ravikrishna Chebolu
  • Convenient process of manufacture for difluoromethylornithine and related compounds
    Patent number: 6998502
    Abstract: A process for the manufacture of ?-Difluoromethylornithine, analogs and derivatives is described from ornithine hydrochloride or from N?-phthaloyl ornithine hydrochloride, conversion to an alkyl ester, conversion to solid derivatives through the formation of Schiff bases, subsequent halomethylation using suitable bases and hydrolysis.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: February 14, 2006
    Assignee: Sabinsa Corporation
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Keshava Rao Rapole, Ravikrishna Chebolu