Patents by Inventor KeshavRao Rapole

KeshavRao Rapole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF NOVEL POLYMORPHIC FORMS OF 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE
    Publication number: 20180009831
    Abstract: Novel polymorphic forms of tavaborole, Form A and Form B, and methods of making same are disclosed. Methods are disclosed for the manufacture of the novel polymorphic Forms A and B. Methods include dissolving tavaborole in a pharmaceutically acceptable solvent to obtain a mixture, heating the mixture until a clear solution is obtained, cooling the clear solution, stirring the clear solution to obtain a crystalline product, filtering the crystalline product, and drying the crystalline product to obtain the pharmaceutically acceptable crystalline form of tavaborole. Pharmaceutical composition are disclosed including a pharmaceutically acceptable crystalline form of tavaborole Form A and/or Form B.
    Type: Application
    Filed: July 5, 2017
    Publication date: January 11, 2018
    Applicant: Apicore US LLC
    Inventors: Ravishanker Kovi, KeshavRao Rapole, Ashish Naik, Vishal Ramani
  • Process for preparing saxagliptin and its novel intermediates useful in the synthesis thereof
    Patent number: 9150511
    Abstract: Methods of making saxagliptin, pharmaceutically acceptable salts and hydrates thereof and intermediates thereof.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: October 6, 2015
    Assignee: Apicore US LLC
    Inventors: Ravishanker Kovi, KeshavRao Rapole, Ashish Naik, Jayaraman Kannapan, Muralikrishna Madala, Sanjay Thakor
  • PROCESS FOR PREPARING SAXAGLIPTIN AND ITS NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF
    Publication number: 20140235870
    Abstract: Methods of making saxagliptin, pharmaceutically acceptable salts and hydrates thereof and intermediates thereof.
    Type: Application
    Filed: April 29, 2014
    Publication date: August 21, 2014
    Applicant: Apicore, LLC
    Inventors: Ravishanker Kovi, KeshavRao Rapole, Ashish Naik, Jayaraman Kannapan, Muralikrishna Madala, Sanjay Thakor
  • Process for preparing saxagliptin and its novel intermediates useful in the synthesis thereof
    Patent number: 8748631
    Abstract: Methods of making saxagliptin, pharmaceutically acceptable salts and hydrates thereof and intermediates thereof.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: June 10, 2014
    Assignee: Apicore, LLC
    Inventors: Ravishanker Kovi, KeshavRao Rapole, Ashish Naik, Jayaraman Kannapan, Murali Krishna Madala, Sanjay F. Thakor
  • PROCESS FOR PREPARING SAXAGLIPTIN AND ITS NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF
    Publication number: 20130023671
    Abstract: Methods of making saxagliptin, pharmaceutically acceptable salts and hydrates thereof and intermediates thereof.
    Type: Application
    Filed: May 24, 2012
    Publication date: January 24, 2013
    Applicant: APICORE, LLC
    Inventors: Ravishanker Kovi, KeshavRao Rapole, Ashish Naik, Jayaraman Kannapan, Murali Krishna Madala, Sanjay F. Thakor