Patents by Inventor Ketki Karanam
Ketki Karanam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11938137Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: January 27, 2022Date of Patent: March 26, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
-
Patent number: 11883497Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: August 29, 2018Date of Patent: January 30, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
-
Patent number: 11608345Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: March 21, 2023Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Sifei Han, Luojuan Hu, Ketki Karanam, Christopher John Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
-
Publication number: 20230062834Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: March 2, 2023Inventors: Daniel Kenneth BONNER, Sifei HAN, Luojuan HU, Ketki KARANAM, Christopher John PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS
-
Publication number: 20220143038Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: January 27, 2022Publication date: May 12, 2022Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
-
Publication number: 20220125933Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: February 28, 2020Publication date: April 28, 2022Inventors: Joseph BOLEN, Daniel Kenneth BONNER, Ketki KARANAM, Christopher John PORTER, Jamie SIMPSON, Natalie TREVASKIS, Dan ZHENG, Nathania LEONG, Garima SHARMA, Mitchell MCINERNEY, Tim QUACH, Sifei HAN
-
Patent number: 11304954Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: April 19, 2022Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
-
Publication number: 20220001015Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 29, 2018Publication date: January 6, 2022Inventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
-
Publication number: 20210300962Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 2, 2019Publication date: September 30, 2021Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Jamie SIMPSON, Christopher John PORTER, Natalie TREVASKIS, Tim QUACH, Sifei HAN, Luojuan HU
-
Publication number: 20200390777Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: December 17, 2020Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Sifei HAN, Luojuan HU, Christopher John Hamilton PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS
-
Patent number: 10559221Abstract: Systems and methods are provided for the implementation of personalized cognitive training. As an example, a processor-implemented method is provided for enhancing cognitive abilities of a user by personalizing cognitive training regimens through difficulty progression. The method includes: performing a cognitive assessment of a user using a set of assessment tasks; estimating a maximal performance of the user related to the set of assessment tasks; determining a performance range based at least in part on the maximal performance of the user; dividing the performance range into a plurality of progress gates, the plurality of progress gates corresponding to a plurality of task difficulty levels; selecting a first progress gate within the performance range; generating a first set of training tasks associated with the first progress gate; and collecting the user's first training responses to the first set of training tasks.Type: GrantFiled: May 20, 2015Date of Patent: February 11, 2020Assignee: Akili Interactive Labs, Inc.Inventors: W. E. Martucci, Adam Piper, Matthew Omernick, Adam Gazzaley, Eric Elenko, Ketki Karanam
-
Publication number: 20200012959Abstract: A system for inducing a physical state in a user. The system includes a sensor associated with the user, an audio output device, and a computer. The computer obtains, from a database, an identification of a type of music associated with a first phase of sleep, and determines, based on data from the sensor, that a user is in a second phase of sleep. Music of the type associated with the first phase of sleep is selected, and the selected music is output to the user through the audio output device.Type: ApplicationFiled: September 17, 2019Publication date: January 9, 2020Applicant: Bose CorporationInventors: Ketki Karanam, Alexis Kopikis, Vikram Krishnan, Nilesh N. Kuchekar, Abby B. Marsh, W. Edward Martucci, Steven A. Sian
-
Publication number: 20180240027Abstract: A predictive method may include determining the strength of a relationship between a user's health state and the user's consumption of media content having one or more features, based on health data and media consumption data corresponding to user consumption of media content items having the feature(s), and predicting an effect of consuming a media content item on the user's health. The prediction may be based on a determination that the strength of the relationship between the health state and the consumption of media content having the one or more features exceeds a threshold strength. A diagnostic method may include determining whether a media consumption signature associated with a health condition matches media consumption data for a population, and diagnosing the population with the health condition based on a determination that the media consumption signature associated with the health condition matches the media consumption data for the population.Type: ApplicationFiled: September 30, 2017Publication date: August 23, 2018Applicant: Bose CorporationInventors: Ketki Karanam, W. Edward Martucci, Alexis Kopikis, Daphne Zohar, Nilesh N. Kuchekar, Abby B. Marsh, Steven A. Sian, Vikram Krishnan
-
Publication number: 20170098385Abstract: Systems and methods are provided for the implementation of personalized cognitive training. As an example, a processor-implemented method is provided for enhancing cognitive abilities of a user by personalizing cognitive training regimens through difficulty progression. The method includes: performing a cognitive assessment of a user using a set of assessment tasks; estimating a maximal performance of the user related to the set of assessment tasks; determining a performance range based at least in part on the maximal performance of the user; dividing the performance range into a plurality of progress gates, the plurality of progress gates corresponding to a plurality of task difficulty levels; selecting a first progress gate within the performance range; generating a first set of training tasks associated with the first progress gate; and collecting the user's first training responses to the first set of training tasks.Type: ApplicationFiled: May 20, 2015Publication date: April 6, 2017Inventors: W. E. Martucci, Adam Piper, Matthew Omernick, Adam Gazzaley, Eric Elenko, Ketki Karanam
-
Publication number: 20160055420Abstract: A predictive method may include determining the strength of a relationship between a user's health state and the user's consumption of media content having one or more features, based on health data and media consumption data corresponding to user consumption of media content items having the feature(s), and predicting an effect of consuming a media content item on the user's health. The prediction may be based on a determination that the strength of the relationship between the health state and the consumption of media content having the one or more features exceeds a threshold strength. A diagnostic method may include determining whether a media consumption signature associated with a health condition matches media consumption data for a population, and diagnosing the population with the health condition based on a determination that the media consumption signature associated with the health condition matches the media consumption data for the population.Type: ApplicationFiled: August 20, 2015Publication date: February 25, 2016Inventors: Ketki Karanam, W. Edward Martucci, Alexis Kopikis, Daphne Zohar, Nilesh N. Kuchekar, Abby B. Marsh, Steven A. Sian, Vikram Krishnan