Patents by Inventor Keuk Chan Bang

Keuk Chan Bang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL HETEROCYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20220064155
    Abstract: The present disclosure relates to a novel heterocyclic amine derivative represented by the following Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers. wherein, in Chemical Formula 1, R1, R2, X1, X2, L, Y, A and B are the same as defined in the specification.
    Type: Application
    Filed: August 27, 2019
    Publication date: March 3, 2022
    Inventors: Wol Young Kim, Yeon Im Lee, Youn Jung Yoon, Joon Seok Park, Deok Ki Eom, Keuk-Chan Bang, Jaehyun Jung
  • SYNTHESIS OF POZIOTINIB DERIVATIVE
    Publication number: 20220064145
    Abstract: A method for the synthesis of a compound of Formula II is provided. Also disclosed is the salt form of the compound. The method includes the introduction of a piperidinyl moiety in a polar aprotic solvent system, followed by the removal of the protecting group and the acrylation step.
    Type: Application
    Filed: August 26, 2021
    Publication date: March 3, 2022
    Applicant: Hanmi Science Co., Ltd.
    Inventors: Keuk Chan Bang, Young Ho Moon, Young Kil Chang
  • 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same
    Patent number: 11180496
    Abstract: The present invention relates to a novel 1H-pyrazolopyridine derivative and a pharmaceutical composition containing the same. The 1H-pyrazolopyridine derivative and the pharmaceutical composition containing the same can be usefully used for the prevention or treatment of autoimmune diseases or cancer.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: November 23, 2021
    Assignee: Daewoong Pharmaceutical Co., Ltd.
    Inventors: Keuk-Chan Bang, Deok Ki Eom, Joon Seok Park
  • Phenylpyridine derivative and pharmaceutical composition comprising the same
    Patent number: 11149019
    Abstract: The present disclosure relates to a novel phenylpyridine derivative represented by Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: October 19, 2021
    Assignee: Daewoong Pharmaceutical Co., Ltd.
    Inventors: Wol-Young Kim, Jung-eun Park, Keuk-Chan Bang, Joon-Seok Park
  • Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same
    Publication number: 20200223821
    Abstract: The present disclosure relates to a novel phenylpyridine derivative represented by Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers.
    Type: Application
    Filed: October 11, 2018
    Publication date: July 16, 2020
    Inventors: Wol-Young Kim, Jung-eun Park, Keuk-Chan Bang, Joon-Seok Park
  • NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20200140432
    Abstract: The present invention relates to a novel 1H-pyrazolopyridine derivative and a pharmaceutical composition containing the same. The 1H-pyrazolopyridine derivative and the pharmaceutical composition containing the same can be usefully used for the prevention or treatment of autoimmune diseases or cancer.
    Type: Application
    Filed: July 12, 2018
    Publication date: May 7, 2020
    Inventors: Keuk-Chan Bang, Deok Ki Eom, Joon Seok Park
  • 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical composition comprising the same
    Patent number: 10399988
    Abstract: The present invention relates to 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same, wherein the 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing them not only have BTK inhibitory activity but also has remarkably high selectivity for the inhibitory activity of BTK vs. ITK, and thereby can be usefully used for the prevention or treatment of autoimmune diseases or cancers as BTK inhibitors.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: September 3, 2019
    Assignee: Daewoong Pharmaceutical Co., Ltd.
    Inventors: Youn-Jung Yoon, Jung-Eun Park, Yeon-Jung Park, Min-June Shim, Keuk-Chan Bang, Joon-Seok Park
  • Novel 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo Derivatives and Pharmaceutical Composition Comprising the Same
    Publication number: 20190161488
    Abstract: The present invention relates to 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same, wherein the 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing them not only have BTK inhibitory activity but also has remarkably high selectivity for the inhibitory activity of BTK vs. ITK, and thereby can be usefully used for the prevention or treatment of autoimmune diseases or cancers as BTK inhibitors.
    Type: Application
    Filed: July 7, 2017
    Publication date: May 30, 2019
    Applicant: Daewoong Pharmaceutical Co., Ltd.
    Inventors: Youn-Jung YOON, Jung-Eun PARK, Yeon-Jung PARK, Min-June SHIM, Keuk-Chan BANG, Joon-Seok PARK
  • Method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yi)prop-2-en-1-one
    Patent number: 9518043
    Abstract: The present invention relates to a novel method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one in a simpler process as compared with conventional methods by allowing 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol to react with an N-acyl piperidine derivative in an inert polar protic solvent in the presence of a base.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: December 13, 2016
    Assignee: Hanmi Pharm. Co., Ltd.
    Inventors: Keuk Chan Bang, Jae Hyuk Jung, Young Ho Moon
  • Method For Preparing 1-(4-(4-(3,4-Dichloro-2-Fluorophenylamino)-7-Methoxyquinazolin-6-Yloxy)Piperidin-1-Yl)Prop-2-En-1-One
    Publication number: 20150344458
    Abstract: The present invention relates to a novel method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one in a simpler process as compared with conventional methods by allowing 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol to react with an N-acyl piperidine derivative in an inert polar protic solvent in the presence of a base.
    Type: Application
    Filed: January 27, 2014
    Publication date: December 3, 2015
    Applicant: HANMI PHARM CO., LTD.
    Inventors: Keuk Chan BANG, Jae Hyuk JUNG, Young Ho MOON
  • Method for preparing tetrazole methanesulfonic acid salts, and novel compound used in same
    Patent number: 8940908
    Abstract: A method for preparing tetrazole methanesulfonic acid salts includes an acylation reaction using a novel 4-iodine-4H-chromene-2-carbothionic acid S-benzothiazole-2-yl ester. The method is advantageous that it can shorten a reaction time and improve safety as compared to conventional methods, and can prepare high-purity tetrazole methanesulfonic acid salts at a high yield rate without using a column chromatography method.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: January 27, 2015
    Assignee: Hanmi Science Co., Ltd
    Inventors: Keuk Chan Bang, Bum Woo Park, Jong Won Choi, Jae Chul Lee, Yong Hoon An, Young Gil Ahn, Maeng Sup Kim
  • Method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-prop-2-en-1-one hydrochloride and intermediates used therein
    Patent number: 8859767
    Abstract: The present invention relates to an improved method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-prop-2-en-1-one hydrochloride, which selectively and effectively inhibits the growth of cancer cells induced by over-expression of an epidermal growth factor receptor (EGFR) and prevents the development of drug resistance caused by mutation of a tyrosine kinase, and intermediates used therein.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: October 14, 2014
    Assignee: Hanmi Science Co., Ltd
    Inventors: Keuk Chan Bang, Young Ho Moon, Young Kil Chang
  • Quinazoline derivatives as a multiplex inhibitor and method for the preparation thereof
    Patent number: 8846699
    Abstract: The present invention relates to a novel quinazoline derivative compound having the formula (1) as follows: with the constituents defined in claim 1, and a pharmaceutically acceptable salt thereof as a multiplex inhibitor, a method for the preparation thereof, and a pharmaceutical composition and a therapeutic composition comprising same as an active ingredient. The inventive quinazoline derivative as a multiplex inhibitor can selectively and effectively inhibit diseases caused by the overactivity of a tyrosine kinase.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: September 30, 2014
    Assignee: Hanmi Pharm. Co., Ltd.
    Inventors: Young-Gil Ahn, Jong Woo Kim, Keuk Chan Bang, Bum Woo Park, Se Young Kim, Kyungik Lee, Kyuhang Lee, Myoung-Sil Ko, Han Kyong Kim, Young Hoon Kim, Maeng Sup Kim, Gwan Sun Lee
  • METHOD FOR PREPARING 1-(4-(4-(3,4-DICHLORO-2-FLUOROPHENYLAMINO)-7-METHOXYQUINAZOLIN-6-YLOXY) PIPERIDIN-1-YL)-PROP-2-EN-1-ONE HYDROCHLORIDE AND INTERMEDIATES USED THEREIN
    Publication number: 20140275534
    Abstract: The present invention relates to an improved method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-prop-2-en-1-one hydrochloride, which selectively and effectively inhibits the growth of cancer cells induced by over-expression of an epidermal growth factor receptor (EGFR) and prevents the development of drug resistance caused by mutation of a tyrosine kinase, and intermediates used therein.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 18, 2014
    Inventors: Keuk Chan Bang, Young Ho Moon, Young Kil Chang
  • METHOD FOR PREPARING TETRAZOLE METHANESULFONIC ACID SALTS, AND NOVEL COMPOUND USED IN SAME
    Publication number: 20140148602
    Abstract: A method for preparing tetrazole methanesulfonic acid salts includes an acylation reaction using a novel 4-iodine-4H-chromene-2-carbothionic acid S-benzothiazole-2-yl ester. The method is advantageous that it can shorten a reaction time and improve safety as compared to conventional methods, and can prepare high-purity tetrazole methanesulfonic acid salts at a high yield rate without using a column chromatography method.
    Type: Application
    Filed: February 3, 2014
    Publication date: May 29, 2014
    Applicant: HANMI SCIENCE CO., LTD
    Inventors: Keuk Chan BANG, Bum Woo PARK, Jong Won CHOI, Jae Chul LEE, Yong Hoon AN, Young Gil AHN, Maeng Sup KIM
  • Method for preparing tetrazole methanesulfonic acid salts, and novel compound used in same
    Patent number: 8680277
    Abstract: According to the present invention, a method for preparing tetrazole methanesulfonic acid salts comprises an acylation reaction using a novel 4-iodine-4H-chromene-2-carbothionic acid S-benzothiazole-2-yl ester. The method of the present invention can shorten a reaction time and improve safety as compared to conventional methods, and can prepare high-purity tetrazole methanesulfonic acid salts at a high yield rate without using a column chromatography method.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: March 25, 2014
    Assignee: Hanmi Science Co., Ltd
    Inventors: Keuk Chan Bang, Bum Woo Park, Jong Won Choi, Jae Chul Lee, Yong Hoon An, Young Gil Ahn, Maeng Sup Kim
  • METHOD FOR PREPARING TETRAZOLE METHANESULFONIC ACID SALTS, AND NOVEL COMPOUND USED IN SAME
    Publication number: 20120330020
    Abstract: According to the present invention, a method for preparing tetrazole methanesulfonic acid salts comprises an acylation reaction using a novel 4-iodine-4H-chromene-2-carbothionic acid S-benzothiazole-2-yl ester. The method of the present invention can shorten a reaction time and improve safety as compared to conventional methods, and can prepare high-purity tetrazole methanesulfonic acid salts at a high yield rate without using a column chromatography method.
    Type: Application
    Filed: January 14, 2011
    Publication date: December 27, 2012
    Applicant: HANMI SCIENCE CO., LTD
    Inventors: Keuk Chan Bang, Bum Woo Park, Jong Won Choi, Jae Chul Lee, Yong Hoon An, Young Gil Ahn, Maeng Sup Kim
  • P-glycoprotein inhibitor, method for preparing the same and pharmaceutical composition comprising the same
    Patent number: 7625926
    Abstract: The bioavailability of an anticancer agent is enhanced when the anticancer agent is administered together with a pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 6, 2004
    Date of Patent: December 1, 2009
    Assignee: Hanmi Pharm. Co., Ltd
    Inventors: Keuk Chan Bang, Mi Young Cha, Young Gil Ahn, Young Jin Ham, Maeng Sup Kim, Gwan Sun Lee
  • Quinazoline Derivatives as a Multiplex Inhibitor and Method For the Preparation Thereof
    Publication number: 20080318950
    Abstract: The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof as a multiplex inhibitor, a method for the preparation thereof, and a pharmaceutical composition and a therapeutic composition comprising same as an active ingredient. The inventive quinazoline derivative as a multiplex inhibitor can selectively and effectively inhibit diseases caused by the overactivity of a tyrosine kinase.
    Type: Application
    Filed: November 8, 2006
    Publication date: December 25, 2008
    Applicant: HANMI PHARM. CO., LTD
    Inventors: Young-Gil Ahn, Jong Woo Kim, Keuk Chan Bang, Bum Woo Park, Se Young Kim, Kyungik Lee, Kyuhang Lee, Myoung-Sil Ko, Han Kyong Kim, Young Hoon Kim, Maeng Sup Kim, Gwan Sun Lee