Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: A system for treating recirculating nutrients using floating media is disclosed. The system is operated in such way that wastewater influent path is changed between a first mode and a second mode at a certain period of time interval. Wastewater influent at the first mode sequentially flows into a first anoxic tank, a second anoxic tank, and an aerobic tank. Wastewater influent at the second mode sequentially flows into the second anoxic tank, the first anoxic tank, and the aerobic tank. Part of the wastewater that flows into the aerobic tank bypasses the first anoxic tank and the second anoxic tank. Part of the wastewater, which flows from the aerobic tank into the first anoxic tank or from the aerobic tank into the second anoxic tank, continuously bypasses the aerobic tank through an internal recirculation pump.