Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: Disclosed herein is a method of controlling the landfill gas generation within the landfill in which leachate is recycled to be continuously injected into a deposit of wastes while extracting the landfill gas from a landfill gas extraction pipe inserted into the waste deposit, comprising steps of: (a) maintaining the recycling leachate at the temperature range of 35° C. to 38° C. and/or the pH of 6.5 to 7.5 until the amount of generated landfill gas reaches from the range of 5% to 20% of a capability of the landfill gas generation in the landfill; (b) maintaining the recycling leachate at the temperature range of 30° C. to 35° C. or the range of 60° C. to 65° C. and/or the pH of 6 to 7 until the amount of generated landfill gas reaches from the range of 75% to 90% of a capability of the landfill gas generation in the landfill; and (c) maintaining the recycling leachate at the temperature range of 35° C. to 38° C. or the range of 50° C. to 54° C. and/or the pH of 6.