Patents by Inventor Keun Gyu Park

Keun Gyu Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230390279
    Abstract: A new use of estrogen-related receptor ? (ERR?) inhibitor in enhancing cancer treatment and a pharmaceutical composition for inhibiting the resistance of cancer to tyrosine kinase inhibitors and enhancing an anticancer effect are disclosed. The pharmaceutical composition contains an ERR? inhibitor as an active ingredient. The pharmaceutical composition for treating tyrosine kinase inhibitor-resistant advanced cancer. The composition can be administered in combination with tyrosine kinase inhibitor. A method for determining if a cancer is tyrosine kinase-resistant is also disclosed.
    Type: Application
    Filed: June 1, 2023
    Publication date: December 7, 2023
    Applicant: NOVMETAPHARMA CO., LTD.
    Inventors: Keun Gyu Park, In Kyu Lee, Sung Jin Cho, Yeon Kyung Choi, Mi Jin Kim, Jung Wook Chin, Yong Hyun Jeon, Jin A Kim, Dong Su Kim, Hoe Yune Jung, Do Hyun Lee
  • Publication number: 20230017330
    Abstract: The present invention relates to a pharmaceutical composition for inhibiting the resistance of liver cancer to sorafenib and enhancing an anticancer effect, comprising an Estrogen-related receptor ? (ERR?) inhibitor as an active ingredient. The present invention can be effectively used as a pharmaceutical composition for treating sorafenib-resistant advanced liver cancer.
    Type: Application
    Filed: November 26, 2020
    Publication date: January 19, 2023
    Applicant: NOVMETAPHARMA CO., LTD.
    Inventors: Keun Gyu PARK, In Kyu LEE, Sung Jin CHO, Yeon Kyung CHOI, Mi Jin KIM, Jung Wook CHIN, Yong Hyun JEON, Jin A KIM, Dong Su KIM, Hoe Yune JUNG
  • Patent number: 9724320
    Abstract: The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-?/Smad signaling, and thus is useful for preventing or treating renal fibrosis.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: August 8, 2017
    Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
    Inventors: In Kyu Lee, Keun Gyu Park, Chang Joo Oh, Han Jong Kim, Joon-Young Kim
  • Publication number: 20160067206
    Abstract: The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-?/Smad signaling, and thus is useful for preventing or treating renal fibrosis.
    Type: Application
    Filed: February 20, 2013
    Publication date: March 10, 2016
    Inventors: In Kyu Lee, Keun Gyu Park, Chang Joo Oh