Abstract: The present invention includes methods and biomarkers for diagnosing or detecting colorectal cancer metastasis in a human subject by comparing the Alu repeat methylation level in the biological sample to an Alu repeat methylation control level from a normal non-cancerous sample from the human subject, wherein a decrease in the Alu repeat methylation level is indicative of colorectal cancer and colorectal cancer metastasis.

Abstract: An apparatus for measuring dissolved gas includes a body having an internal space, a separator installation part provided in the body and having a separator allowing a dissolved gas to pass therethrough and blocking insulating oil installed therein, and a sensor installation part provided in the body and allowing a gas sensor measuring dissolved gas separated by the separator to be installed therein, wherein the separator installation part and the sensor installation part are configured in such a manner that the separator and the gas sensor are independently installed in the body or separated from the body. According to the apparatus for measuring dissolved gas, a gas sensor may be manufactured to be standardized, and excellent compatibility with respect to various types of gas sensors may be provided.

Abstract: Methods and compositions for the diagnosis, prognosis and classification of cancer, especially colorectal cancer, are provided. For example, in certain aspects methods for cancer prognosis using expression or methylation analysis of selected biomarkers are described. Particular aspects of the present invention may include methods and biomarkers for diagnosing or detecting colorectal cancer or metastasis in a subject by measuring a level of expression of biomarker miRNA such as miR-885-5p in the sample from the subject and evaluating the risk of developing cancer or metastasis in the subject.

Abstract: An apparatus for measuring dissolved gas includes a body having an internal space, a separator installation part provided in the body and having a separator allowing a dissolved gas to pass therethrough and blocking insulating oil installed therein, and a sensor installation part provided in the body and allowing a gas sensor measuring dissolved gas separated by the separator to be installed therein, wherein the separator installation part and the sensor installation part are configured in such a manner that the separator and the gas sensor are independently installed in the body or separated from the body. According to the apparatus for measuring dissolved gas, a gas sensor may be manufactured to be standardized, and excellent compatibility with respect to various types of gas sensors may be provided.

Abstract: The present invention includes methods and biomarkers for diagnosing or detecting colorectal cancer metastasis in a human subject by comparing the Alu repeat methylation level in the biological sample to an Alu repeat methylation control level from a normal non-cancerous sample from the human subject, wherein a decrease in the Alu repeat methylation level is indicative of colorectal cancer and colorectal cancer metastasis.

Abstract: Methods and compositions for the diagnosis, prognosis and classification of cancer, especially colorectal cancer, are provided. For example, in certain aspects methods for cancer prognosis using expression or methylation analysis of selected biomarkers are described. Particular aspects of the present invention may include methods and biomarkers for diagnosing or detecting colorectal cancer or metastasis in a subject by measuring a level of expression of biomarker miRNA such as miR-885-5p in the sample from the subject and evaluating the risk of developing cancer or metastasis in the subject.

Abstract: The present invention includes methods, kits and biomarkers for detecting and determining the development of colorectal cancer (CRC) metastasis based on changes in the expression pattern of one or more microRNAs (miR) or miR clusters that include the miR-200/141 family.

Abstract: A method for determining a colorectal cancer metastasis in a human subject suffering from a primary colorectal cancer (CRC) is described herein. The method of the present invention comprises the steps of: i) identifying the human subject suffering from the primary CRC, ii) obtaining one or more biological samples from the human subject, iii) detecting a methylation level of Alu, LINE-1, or both in the one or more biological samples, and iv) increasing the level of the colorectal metastatic stage in the human subject when the methylation level of Alu, LINE-1 is lower compared to a corresponding control methylation level of Alu, LINE-1.