Abstract: Embodiments provide for anti-GPC3 antibodies compositions comprising the same, and methods of using such antibodies and compositions for the prevention, diagnosis, and treatment of cancer. In one embodiment, a method for predicting a therapeutic effect of an anti-GPC3 immunotherapy on a cancer characterized in that cells of the cancer express GPC3, comprises detecting the presence of said cells in a subject via an immunohistochemical methodology, and wherein when the presence of said cells is detected, the anti-GPC3 immunotherapy is predicted to have a therapeutic effect on the cancer in the subject.

Abstract: A system for prioritizing work orders including determining a score based on timing data and compare the determined score of the subject vehicle to one or more other scores associated with one or more other vehicles. The system includes generating an updated list of work orders based on the scores and displaying the updated list on a graphical user interface of an electronic device.

Abstract: The present disclosure relates to devices and processes for monitoring attributes of a user's physical activity (e.g., workout) or inactivity, and to user interfaces (e.g., an activity indicator) for displaying the same.

Abstract: Disclosed is a device for application of a sticker or decal on a surface difficult to position or align. Also disclosed is a method of using a device for application of a sticker or decal on a surface.

Abstract: Disclosed is a device for application of a sticker or decal on a surface difficult to position or align. Also disclosed is a method of using a device for application of a sticker or decal on a surface.

Abstract: A surface treatment apparatus may include a power source having one or more batteries and an apparatus controller configured to estimate a state of charge of the one or more batteries based, at least in part, on an operational mode of the surface treatment apparatus.

Abstract: A mixed density fluid separator and systems for separating fluids of different densities, as well as kits and methods employing the same, are provided. The mixed density fluid separator generally comprises a fluid separation tank having a valve control system and a vacuum pump to direct fluid processing. The tank includes an upper float ball valve having a neutrally buoyant float ball slideably retained therein by a vertically elongated guide cage that is at least twice as long as the diameter of the float ball. The mixed density fluid separator can be adapted for multiple different uses, including with rapid deployment oil-spill cleanup kits that are sufficiently lightweight and compact for easy transport, access and application.

Abstract: In an articulating probe system, an articulating probe is constructed and arranged to articulate in at least one degree of motion and to transition between a flexible state and a rigid state, the articulating probe comprising a plurality of links between a proximal link and a distal link. The distal link of the articulating probe includes a side port constructed and arranged to receive a distal end of an elongate tool. A tool support is in communication with the articulating probe for supporting the elongate tool, the tool support including a tool tube that extends from the tool support at an intermediate portion to the side port of the distal link at a distal portion, the tool tube having a first flexibility in the intermediate portion and having a second flexibility in the distal portion; the second flexibility being greater in flexibility than the first flexibility.

Abstract: A mixed density fluid separator and systems for separating fluids of different densities, as well as kits and methods employing the same, are provided. The mixed density fluid separator generally comprises a fluid separation tank having a valve control system and a vacuum pump to direct fluid processing. The tank includes an upper float ball valve having a neutrally buoyant float ball slideably retained therein by a vertically elongated guide cage that is at least twice as long as the diameter of the float ball. The mixed density fluid separator can be adapted for multiple different uses, including with rapid deployment oil-spill cleanup kits that are sufficiently lightweight and compact for easy transport, access and application.

Abstract: An oil-water separator for separating mixed density fluids, such as oil and water, oily sediment laden water and the like, as well as portable, in-tank and towable and anchorable boom containment systems kits and methods employing the same. The oil-water separator employs at least two oil-separation chambers operating in opposing but synergistic separation modes in parallel. The oil-separation chambers alternate distribution of a single mixed fluid density stream between the chambers using a partial vacuum source to draw the stream into one chamber, while concurrently stopping inflow of the stream into another chamber by removing the vacuum source. The apparatus allows each chamber to switch back and forth between (a) actively separating and removing less dense fluid (e.g., oil) when the partial vacuum is applied, and (b) passively separating the less dense fluid (e.g., oil) and removing the more dense fluid (e.g., water) when the partial vacuum source is removed.

Abstract: The present disclosure includes switching regulator circuits and methods. In one embodiment, a first switching regulator stage receives a first input voltage and produces a first voltage on a first node. A second switching regulator stage receives the first input voltage and produces a second voltage on a second node. A capacitor includes a first terminal coupled to the first node and a second terminal coupled to the second node, and the first switching regulator stage and the second switching regulator stage are configured to set a first voltage on the first node and to set a second voltage on the second node.

Abstract: In an articulating probe system, an articulating probe is constructed and arranged to articulate in at least one degree of motion and to transition between a flexible state and a rigid state, the articulating probe comprising a plurality of links between a proximal link and a distal link The distal link of the articulating probe includes a side port constructed and arranged to receive a distal end of an elongate tool. A tool support is in communication with the articulating probe for supporting the elongate tool, the tool support including a tool tube that extends from the tool support at an intermediate portion to the side port of the distal link at a distal portion, the tool tube having a first flexibility in the intermediate portion and having a second flexibility in the distal portion; the second flexibility being greater in flexibility than the first flexibility.

Abstract: The aggregation of multiple inputs in a touch-sensitive input device is disclosed. For example, one disclosed embodiment comprises receiving multiple inputs related to a virtual object, aggregating the inputs into an aggregated output, and providing the aggregated output to an application that controls the virtual object.

Abstract: An oil-water separator for separating mixed density fluids, such as oil and water, oily sediment laden water and the like, as well as portable, in-tank and towable and anchorable boom containment systems kits and methods employing the same. The oil-water separator employs at least two oil-separation chambers operating in opposing but synergistic separation modes in parallel. The oil-separation chambers alternate distribution of a single mixed fluid density stream between the chambers using a partial vacuum source to draw the stream into one chamber, while concurrently stopping inflow of the stream into another chamber by removing the vacuum source. The apparatus allows each chamber to switch back and forth between (a) actively separating and removing less dense fluid (e.g., oil) when the partial vacuum is applied, and (b) passively separating the less dense fluid (e.g., oil) and removing the more dense fluid (e.g., water) when the partial vacuum source is removed.

Abstract: A fluid distributor has a component configured for selective rotation about a central axis of the fluid distributor, a fluid input, a first fluid output, and a second fluid output, wherein rotation of the component in a first direction about the central axis alternates selection between the first fluid output and the second fluid output and at least one of (1) the component is configured to rotate about the central axis by at least 360° in the first direction and such rotation of the component about the central axis provides at least four alternations between selection of the first fluid output and the second fluid output and (2) selection of the second fluid output is the next available fluid output for selection in response to rotating the component about the central axis away from a position of the component in which the first fluid output is selected.

Abstract: Embodiments of the disclosure include high slew rate switching regulator circuits and methods. In one embodiment, switching regulators are coupled to an output node. A first switching regulator may drive the output node. A second switching regulator may drive the output node through a capacitor. Control circuitry may include feedback inputs to maintain a first voltage on the output of the first switching regulator on one terminal of the capacitor and further to maintain a second voltage on the output of the second switching regulator on the other terminal of the capacitor.

Abstract: This invention relates generally to products and processes, and more specifically, to systems and method for recovering oil from water. In one embodiment, a towed net system is provided which has the ability to collect free floating oil to one or more end points from which either/both hydrodynamics and/or one or more powered pumps are used to deliver channeled and collected oil to one or more receiving vessels. In some embodiments, two wing nets are provided, either/each towed by one or more vessels, connected to one or more end receptacle nets. From the one or more end receptacles, the channeled and collected oil is delivered to one or more receiving containers also connected to the one or more end receptacles. The system can be scaled based on the horsepower of the two or more towing vessel.

Abstract: Descriptions of files detected at endpoints are submitted to a security server. The descriptions describe the names of the files and unique identifiers of the files. The security server uses the unique identifiers to identify files having different names at different endpoints. For a given file having multiple names, the names are processed to account for name differences unlikely to have been caused by malware. The processed names for the file are analyzed to determine the amount of dissimilarity among the names. This analysis is used to generate a score indicating a confidence that the computer file contains malicious software, where a greater amount of dissimilarity among the names generally indicates a greater confidence that the computer file contains malicious software. The score is weighted based on file name frequency, the age of the file, and the prevalence of the file. The weighted score is used to determine whether the computer file contains malicious software.

Abstract: A fluid distributor has a component configured for selective rotation about a central axis of the fluid distributor, a fluid input, a first fluid output, and a second fluid output, wherein rotation of the component in a first direction about the central axis alternates selection between the first fluid output and the second fluid output and at least one of (1) the component is configured to rotate about the central axis by at least 360° in the first direction and such rotation of the component about the central axis provides at least four alternations between selection of the first fluid output and the second fluid output and (2) selection of the second fluid output is the next available fluid output for selection in response to rotating the component about the central axis away from a position of the component in which the first fluid output is selected.

Abstract: The aggregation of multiple inputs in a touch-sensitive input device is disclosed. For example, one disclosed embodiment comprises receiving multiple inputs related to a virtual object, aggregating the inputs into an aggregated output, and providing the aggregated output to an application that controls the virtual object.