Abstract: A traceable cable and method of forming the same. The cable includes at least one data transmission element, a jacket at least partially surrounding the at least one data transmission element, and a side-emitting optical fiber incorporated with and extending along at least a portion of the length of the cable. The side-emitting optical fiber has a core and a cladding substantially surrounding the core to define an exterior surface. The cladding has spaced apart scattering sites penetrating the exterior surface along the length of the optical fiber. The scattering sites scattering light so that the scattered light is emitted from the side-emitting optical fiber at discrete locations. When light is transmitted through the core, light scattered from the side-emitting optical fiber allows the cable to be traced along at least a portion of the length thereof.

Abstract: A method for measuring a mechanical property of a coating on an optical fiber may include collecting Brillouin frequency shift data of the coating on the optical fiber, and determining the mechanical property of the coating by comparing the collected Brillouin frequency shift data with correlation data that may include a set of collected sample Brillouin frequency shift data and a set of collected sample mechanical property data of a plurality of sample materials. The sample materials may include a substantially identical sample composition including one or more curable polymers, be prepared with varying processing conditions, and have different mechanical property values. The coating on the optical fiber may include a material composition substantially identical to the sample materials composition. The set of collected sample Brillouin frequency shift data may be correlated with the set of collected sample mechanical property data to determine a quantitative relationship therebetween.

Abstract: A traceable cable and method of forming the same. The cable includes at least one data transmission element, a jacket at least partially surrounding the at least one data transmission element, and a side-emitting optical fiber incorporated with and extending along at least a portion of the length of the cable. The side-emitting optical fiber can have a core, spaced apart scattering sites having scattering material disposed on an exterior surface of the core along the length of the optical fiber, and a cladding substantially surrounding the core and the scattering material. The scattering sites are capable of scattering light so that the scattered light is emitted from the side-emitting optical fiber at discrete locations proximate to the scattering sites. When light is transmitted through the core, light scattered from the side-emitting optical fiber allows the cable to be traced along at least a portion of the length thereof.

Abstract: Optical fibers having a mode field diameter at 1310 nm of at least 8.8 ?m, wire mesh covered drum microbending losses at 1550 nm less than 0.03 dB/km, and a 2 m cutoff wavelength less than 1320 nm. The fibers may include a central core region, an inner cladding region, an outer cladding region, a primary coating with an in situ modulus less than 0.20 MPa and glass transition temperature less than ?35° C., and a secondary coating with an in situ modulus greater than 1500 MPa. The fibers may further include a depressed index cladding region. The relative refractive index of the central core region may be greater than the relative refractive index of the outer cladding region may be greater than the relative refractive index of the inner cladding region. The fibers may be produced at draw speeds of 30 m/s or greater.

Abstract: A method for measuring a mechanical property of a coating on an optical fiber may include collecting Brillouin frequency shift data of the coating on the optical fiber, and determining the mechanical property of the coating by comparing the collected Brillouin frequency shift data with correlation data that may include a set of collected sample Brillouin frequency shift data and a set of collected sample mechanical property data of a plurality of sample materials. The sample materials may include a substantially identical sample composition including one or more curable polymers, be prepared with varying processing conditions, and have different mechanical property values. The coating on the optical fiber may include a material composition substantially identical to the sample materials composition. The set of collected sample Brillouin frequency shift data may be correlated with the set of collected sample mechanical property data to determine a quantitative relationship therebetween.

Abstract: A traceable cable and method of forming the same. The cable includes at least one data transmission element, a jacket at least partially surrounding the at least one data transmission element, and a side-emitting optical fiber incorporated with and extending along at least a portion of the length of the cable. The side-emitting optical fiber can have a core, spaced apart scattering sites having scattering material disposed on an exterior surface of the core along the length of the optical fiber, and a cladding substantially surrounding the core and the scattering material. The scattering sites are capable of scattering light so that the scattered light is emitted from the side-emitting optical fiber at discrete locations proximate to the scattering sites. When light is transmitted through the core, light scattered from the side-emitting optical fiber allows the cable to be traced along at least a portion of the length thereof.

Abstract: Optical fibers having a mode field diameter at 1310 nm of at least 8.8 ?m, wire mesh covered drum microbending losses at 1550 nm less than 0.03 dB/km, and a 2 m cutoff wavelength less than 1320 nm. The fibers may include a central core region, an inner cladding region, an outer cladding region, a primary coating with an in situ modulus less than 0.20 MPa and glass transition temperature less than ?35° C., and a secondary coating with an in situ modulus greater than 1500 MPa. The fibers may further include a depressed index cladding region. The relative refractive index of the central core region may be greater than the relative refractive index of the outer cladding region may be greater than the relative refractive index of the inner cladding region. The fibers may be produced at draw speeds of 30 m/s or greater.

Abstract: A traceable cable and method of forming the same. The cable includes at least one data transmission element, a jacket at least partially surrounding the at least one data transmission element, and a side-emitting optical fiber incorporated with and extending along at least a portion of the length of the cable. The side-emitting optical fiber has a core and a cladding substantially surrounding the core to define an exterior surface. The cladding has spaced apart scattering sites penetrating the exterior surface along the length of the optical fiber. The scattering sites scattering light so that the scattered light is emitted from the side-emitting optical fiber at discrete locations. When light is transmitted through the core, light scattered from the side-emitting optical fiber allows the cable to be traced along at least a portion of the length thereof.

Abstract: Optical fibers having a mode field diameter at 1310 nm of at least 8.8 ?m, wire mesh covered drum microbending losses at 1550 nm less than 0.03 dB/km, and a 2 m cutoff wavelength less than 1320 nm. The fibers may include a central core region, an inner cladding region, an outer cladding region, a primary coating with an in situ modulus less than 0.20 MPa and glass transition temperature less than ?35° C., and a secondary coating with an in situ modulus greater than 1500 MPa. The fibers may further include a depressed index cladding region. The relative refractive index of the central core region may be greater than the relative refractive index of the outer cladding region may be greater than the relative refractive index of the inner cladding region. The fibers may be produced at draw speeds of 30 m/s or greater.

Abstract: A traceable cable and method of forming the same. The cable includes at least one data transmission element, a jacket at least partially surrounding the at least one data transmission element, and a side-emitting optical fiber incorporated with and extending along at least a portion of the length of the cable. The side-emitting optical fiber has a core and a cladding substantially surrounding the core to define an exterior surface. The cladding has spaced apart scattering sites penetrating the exterior surface along the length of the optical fiber. The scattering sites scattering light so that the scattered light is emitted from the side-emitting optical fiber at discrete locations. When light is transmitted through the core, light scattered from the side-emitting optical fiber allows the cable to be traced along at least a portion of the length thereof.

Abstract: Optical fibers having a mode field diameter at 1310 nm of at least 8.8 ?m, wire mesh covered drum microbending losses at 1550 nm less than 0.03 dB/km, and a 2 m cutoff wavelength less than 1320 nm. The fibers may include a central core region, an inner cladding region, an outer cladding region, a primary coating with an in situ modulus less than 0.20 MPa and glass transition temperature less than ?35° C., and a secondary coating with an in situ modulus greater than 1500 MPa. The fibers may further include a depressed index cladding region. The relative refractive index of the central core region may be greater than the relative refractive index of the outer cladding region may be greater than the relative refractive index of the inner cladding region. The fibers may be produced at draw speeds of 30 m/s or greater.

Abstract: Controlled-release dosage formulations including at least one compound of Formulae I to XXVIII herein and a controlled-release carrier and methods of treatment using the same are provided.

Abstract: Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations of a hepatitis C virus (HCV) protease inhibitor and an aldo-keto reductase (AKR) competitor, for concurrent or consecutive administration in treating, preventing, or ameliorating one or more symptoms of HCV, treating disorders associated with HCV, or inhibiting cathepsin activity in a subject.

Abstract: Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations of a hepatitis C virus (HCV) protease inhibitor and an aldo-keto reductase (AKR) competitor, for concurrent or consecutive administration in treating, preventing, or ameliorating one or more symptoms of HCV, treating disorders associated with HCV, or inhibiting cathepsin activity in a subject.

Abstract: In its many embodiments, the present invention provides a novel class of compounds of structural formula I as inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.

Abstract: Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations of a hepatitis C virus (HCV) protease inhibitor and an aldo-keto reductase (AKR) competitor, for concurrent or consecutive administration in treating, preventing, or ameliorating one or more symptoms of HCV, treating disorders associated with HCV, or inhibiting cathepsin activity in a subject.

Abstract: The use of CCR5 antagonists of the formula or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R1 is hydrogen or alkyl; R2 is substituted phenyl, substituted heteroaryl, naphthyl, fluorenyl, diphenylmethyl or optionally substituted phenyl- or heteroaryl-alkyl; R3 is hydrogen, alkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, or optionally substituted phenyl, phenylalkyl, naphthyl, naphthylalkyl, heteroaryl or heteroarylalkyl; R4, R5 and R7 are hydrogen or alkyl; R6 is hydrogen, alkyl or alkenyl; for the treatment of HIV, solid organ transplant rejection, graft v.

Abstract: The present invention is directed to a metabolite of a xanthine Phosphodiesterase type 5 inhibitor having the following structure derivatives, and formulations thereof, and processes for preparing the same.