Abstract: A rotor blade system. The rotor blade system includes a rotor and a plurality of blades coupled to the rotor. The plurality of blades are arranged in an airfoil distribution pattern. The airfoil distribution pattern includes one or more baseline blades and one or more intentionally mistuned blades including an intentional mistuning feature.

Abstract: Data backups are performed in multiple blockchain environments. Digital pictures, movies, computer files, apps, and any other electronic data may be automatically backed-up, or duplicated, to multiple blockchain networks. First, an electronic data is written to a first blockchain network. A second, different, blockchain network is automatically selected based on many factors and/or parameters. Then, the electronic data is written to the second blockchain network. Still more duplicate copies of the electronic data may be redundantly written to third, fourth, and more blockchain networks. Any of the blockchain networks may send a confirmation that confirms the duplicate copy was written. One or more cryptographic proofs may be generated to prove the duplicate copies were stored to the multiple blockchain networks.

Abstract: An electrical flat socket contact device for an electrical power connection includes a carrier structure, wherein the carrier structure forms a primarily cuboid contact box unit, into which a primarily cuboid tab contact for electrically contacting the flat socket contact device can be plugged; and a primarily cuboid contact body arranged in the contact box unit for contacting the tab contact plugged into the contact box unit, wherein the contact body is arranged on a base wall of the carrier structure, wherein on a top wall of the carrier structure arranged opposite the base wall there is arranged at least one spring element unit for mechanically contacting the tab contact, and wherein the top wall has at least twice the wall thickness of the base wall.

Abstract: An internal combustion engine-based system includes an internal combustion engine. The internal combustion engine-based system includes an engine interrupt connected to the engine. The engine interrupt is configured to selectively stop the operation of the engine. The internal combustion engine-based system includes a controller in communication with the engine interrupt. The internal combustion engine-based system includes a carbon monoxide detector in communication with the controller. The controller uses the engine interrupt to stop the operation of the engine when the carbon monoxide detector provides the controller with signals that are representative of a carbon monoxide level proximate the internal combustion engine that together form a trend of building carbon monoxide amounts over a set time interval.

Abstract: Systems and methods for network device management are described. An indication of a failed network connection between a first user device and a second network device can be received. Using data from the first network device, the first user device, at least one second network device, and/or at least one second user device, one or more characteristics of the first network device and/or the at least one second network device can be determined. Modification of the determined one or more characteristics can be caused.

Abstract: The systems and methods of the present disclosure provide connectable tiles that can form a self-contained illuminated sign of potentially unlimited size. The self-contained illuminated sign can include one or more tiles. A tile can include a diffusion film having a surface to be illuminated. The tile can include a light guide plate coupled to the diffusion film. The light guide can be configured to evenly distribute light through the diffusion film. The tile can include a solar panel coupled to the light guide. The solar panel can capture light that passes through the diffusion film and the light guide. The tile can include a light source positioned adjacent to the light guide that receives stored electrical power from a battery electrically coupled to the solar panel. The tile can include a connector configured to attach the tile to a second tile.

Abstract: Medical devices for cinching and cutting one or more suture, and methods for making and using such devices are disclosed. An example medical device may include a shaft, a sleeve attached to the shaft, cutter slidable within the sleeve, a cinch sleeve releasably coupled to the sleeve, and a cinch member. An elongated inner shaft may extend through and be longitudinally movable within the elongated shaft, sleeve, cutter, cinch sleeve, and cinch member. The inner shaft may be actuated to cinch and cut one or more suture disposed within the device.

Abstract: The disclosed embodiments concern methods, systems and computer program products for determining sequences of interest using unique molecular indexes (UMIs) that are uniquely associable with individual polynucleotide fragments, including sequences with low allele frequencies or long sequence length. In some implementations, the UMIs include variable-length nonrandom UMIs (vNRUMIs). Methods and systems for making and using sequencing adapters comprising vNRUMIs are also provided.

Abstract: Techniques are described for providing virtual networking functionality for managed computer networks. In some situations, a user may configure or otherwise specify a logical network topology for a managed computer network with multiple computing nodes that includes one or more virtual networking devices each associated with a specified group of the multiple computing nodes. Corresponding networking functionality may be provided for communications between the multiple computing nodes by emulating functionality that would be provided by the networking devices if they were physically present and configured to support the specified network topology. In some situations, the managed computer network is a virtual computer network overlaid on a substrate network, and the networking device functionality emulating includes receiving routing communications directed to the networking devices and using included routing information to update the specified network topology for the managed computer network.

Abstract: The present invention relates to RNAi agents, e.g., dsRNA agents, targeting the Sodium-glucose cotransporter-2 (SGLT2) gene. The invention also relates to methods of using such RNAi agents to inhibit expression of a SGLT2 gene and to methods of treating or preventing a SGLT2-associated disease, such as gout or diabetes, in a subject.

Abstract: The present disclosure describes a multi-analyte sensor system that detects artifacts using multiple analytes. According to an embodiment, the multi-analyte sensor system includes a first analyte sensor, a second analyte sensor, and a sensor electronics module. The first analyte sensor produces a first analyte signal stream indicating a level of a first analyte. The second analyte sensor produces a second analyte signal stream indicating a level of a second analyte different from the first analyte. The sensor electronics module detects, based on the first analyte signal stream and the second analyte signal stream, at least one of a compression event or a dip and recover event and in response to detecting at least one of the compression event or the dip and recover event, make an adjustment related to at least one of the first analyte sensor or the first analyte signal stream based on the event.

Abstract: A magnetically driven pressure generator including a housing, flexible member, first magnetic force generator, and second magnetic force generator. The magnetically driven pressure generator oscillates the flexible member to increase or decrease the volume of a chamber, inversely increasing or decreasing the pressure of the chamber.

Abstract: The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria.

Abstract: A modular trailer wall system for containing loads. The trailer system is detachably attached to a deck of a utility trailer, the deck and wall system being adapted to be towed by a vehicle. The wall system has two side walls extending upwardly from the pair of lateral edges of the deck. A front wall extends upwardly from the leading edge of the deck. A removable, adjustably located partition extends upwardly from the deck. The removable partition is adapted to extend between the two side walls at a position that lies above or ahead of the trailing edge of the deck. Locking mechanisms detachably attach the removable partition in its upright position to one or more of the side walls. Attachment mechanisms detachably secure the wall system to the deck.

Abstract: One variation of a method includes: detecting a set of radio signals transmitted between a set of computing devices and a set of access points in the space; for each radio signal in the set of radio signals, extracting a pair of unique identifiers representing an initial computing device and an initial access point from the radio signal; storing the pair of unique identifiers in a set of containers; accessing a known position of the wireless sensor; accessing a signal transmission range of an access point based on the set of containers; deriving a signal strength of a radio signal based on the known position and the signal transmission range; in response to the signal strength exceeding a threshold signal strength, deriving a location unit occupied by the access point; and aggregating the location unit into a localization map representing locations of the set of access points in the space.

Abstract: A combustor section support structure can include a fuel manifold and one or more radial stud assemblies connected to the fuel manifold and configured to allow the fuel manifold to move radially relative to an engine case and to fix the fuel manifold axially relative to the engine case. Each of the one or more radial stud assemblies can include a first portion mounted to the fuel manifold and a second portion configured to mount to an engine case. The first portion and the second portion can be configured to slide relative to each other to allow relative radial movement, but to prevent substantial axial relative movement. The first portion and the second portion form a ball joint assembly configured to allow misalignment induced rotation at the ball joint assembly.

Abstract: An instrument panel includes a frame defining an opening, a plurality of cards, and an HMI. The cards have a front face, a rear face, one or more circuits, and a data interface on the rear face in communication with the circuits. The cards include one or more first cards and one or more second cards. The first cards front face have a vertical dimension approximately equal to a vertical dimension of the opening. The second cards have a body, a nose projecting from the body defining the second cards front face, and a recess between the nose and body. The HMI includes a front face received within the opening. The first cards are positioned with the front face visible within the opening. The second cards are positioned with the nose visible within the opening and a depth of the HMI received within the recess.

Abstract: Methods for intra-mold sterilization of a plastic-embedded metal component of a product, such as a medical lancet having a metal needle embedded within a plastic lancet body. For example, a lancet needle is retained within a mold, plastic is injected to encapsulate the needle, and a specified minimum temperature is maintained for a specified minimum cycle time. In example forms, the specified minimum mold temperature is at least about 370 degrees Fahrenheit and the specified minimum cycle time is at least about 10 seconds.

Abstract: Methods for characterizing fluids from a patient. A time series of images of a conduit are received, and a conduit image region in the images is identified. The conduit image region may include a shallow section and/or a deep section. The shallow section includes a dimension of the conduit along an optical axis of the camera such that opacity of the fluids from redness associated with red blood cells or hemoglobin is limited to permit pixel color visualization in the images. The deep section includes a dimension is along the optical axis such that the redness provides a minimum opacity to permit the pixel color visualization. A concentration of a blood component of the fluids is determined based on the pixel color visualization. A volume of blood passing through the conduit is estimated based on the estimated concentration of the blood component and an estimated volumetric flow rate.

Abstract: A filter element has a holder arrangement with a filter bellows and a partition element arranged at different regions of the holder arrangement. The partition element extends between first and second chambers of a resonator structure when installed in a filter system and has a passage acoustically coupling the two chambers. Such a filter element is exchangeably arranged in the filter housing of the filter system which has a main inlet, a main outlet, and an auxiliary connection outlet. The filter bellows is arranged in flow direction between the main inlet and the two outlets. The partition element is arranged between the two chambers of the resonator structure for noise damping of the auxiliary connection outlet. Its passage acoustically couples the two chambers. The partition element projects into an auxiliary connection resonator region of the filter housing and has end regions contacting walls delimiting the auxiliary connection resonator region.