Abstract: A catheter may include an elongate body including a proximal portion including a proximal end, and a distal tip portion. The distal tip portion may include an inner liner and a marker band circumferentially surrounding the inner liner. The distal tip portion also may include an outer jacket circumferentially surrounding a first portion of the inner liner and ending proximal of a proximal end of the marker band; and a tip outer jacket circumferentially surrounding a second portion of the inner liner and the marker band. The tip outer jacket extends distally past the marker band distal end to a distal tip of the elongate body, and a proximal end of the tip outer jacket may be laterally adjacent to a distal end of the outer jacket.

Abstract: Methods of assaying a breath sample from a subject for the presence of one or more toxins or toxin associated compounds are provided. In some embodiments, the one or more toxins or toxin associated compounds includes trichloroethylene (TCE) and/or one or more metabolites thereof. Embodiments of the methods further include providing a toxin exposure assessment that can be used to determine if the subject has been exposed to a toxin and to monitor changes in toxin exposure over time in the subject. In certain embodiments, a machine learning model may be used to determine if a subject has been exposed to one or more toxins.

Abstract: Embodiments include overflow sensor assemblies for water heaters, HVAC systems, and other devices for which temperature control systems may be used. An example overflow sensor assembly for detecting fluid leaks at a device may include a sensor probe configured to be in electrical communication with a power supply, and a sensor mounting bracket that forms a ground, where the sensor mounting bracket is configured to be adjustably coupled to a mounting surface on the device, such that the sensor mounting bracket can deflect about the mounting surface. The sensor probe is suspended from the sensor mounting bracket.

Abstract: Provided herein is a disinfecting device including a container containing a chlorhexidine-based solution having a chlorhexidine concentration of from 0.2-2.0% wt/vol. Provided also is a medical connector disinfected with the disinfecting device. A method of disinfecting a medical connector using the disinfecting device is also disclosed.

Abstract: The present invention relates to systems and methods for improved building systems management and maintenance. The present invention provides a system for providing an augmented reality-like interface for the management and maintenance of building systems, specifically the mechanical, electrical, and plumbing (MEP) systems within a building, including the heating, ventilation, and air-conditioning (HVAC) systems.

Abstract: New or improved lead acid batteries with vapor pressure barriers and/or improved battery separators, as well as systems, vehicles, and/or methods of manufacture and/or use thereof are disclosed herein. In at least select embodiments, the instant disclosure provides new or improved lead acid batteries with a vapor pressure barrier. In at least select embodiments, the instant disclosure provides new or improved lead acid battery vapor pressure barriers along with new or improved battery separators, and/or methods of manufacture and/or use thereof. In at least select embodiments, the instant disclosure provides a new or improved lead acid battery with a vapor pressure barrier that reduces the water loss from the battery. In at least select embodiments, a method of reducing the water loss of a lead acid battery may include providing a vapor pressure barrier, such as a layer of oil, inside the lead acid battery along with an improved battery separator.

Abstract: A connector for use in a respiratory system. The connector can connect a first respiratory system component such as a filter to a second respiratory system component. The connector has a body defining a bore for receipt of a complementary connector component. The bore has a terminal end that provides an entry into the bore for the complementary connector component. The connector comprises at least one internal retaining feature, at least one internal alignment feature, and/or at least one external alignment feature.

Abstract: An automated carrier system is disclosed for moving objects to be processed. The automated carrier system includes a discontinuous plurality of track sections on which an automated carrier may be directed to move, and the automated carrier includes a base structure on which an object may be supported, and at least two wheels assemblies being pivotally supported on the base structure for pivoting movement from a first position to a second position to effect a change in direction of movement of the carrier.

Abstract: An oral feline feed and a method of controlling fleas in a feline in need thereof by orally administering to the feline a daily feed comprising an effective amount of a spinosyn for an effective time to thereby cause the amount of spinosyn in the feline's blood to rise to and be maintained at a therapeutically effective level for controlling fleas.

Abstract: A method for switching railcars at a railroad yard includes accessing a list of selected railcars for an outgoing train. The method further includes generating a plurality of train consists that each comply with a set of train rules. The method further includes displaying indications of the generated train consists and their associated number of railyard switch moves on an electronic display. The method further includes receiving a user selection of a desired train consist from the plurality of displayed train consists. The method further includes generating a plurality of switch lists according to the desired train consist and a current inventory of railcars in the railyard. The switch lists include instructions about how to form the desired train consist in the railyard. The method further includes displaying the plurality of switch lists on the electronic display.

Abstract: Mounting assemblies for waste disposers such as food waste disposers, waste disposers employing such mounting assemblies, and related methods are disclosed herein. Mounting assemblies include an engagement feature having a first engagement structure located on the body flange and a second engagement structure located on the upper portion of the disposer body. When the engagement feature is in the engaged position, the body flange and the disposer body are engaged, forming a combined disposer and body flange assembly. The combined disposer and body flange assembly can be lifted into alignment with the strainer flange assembly and rotated as a unit to engage the body flange with the mounting flange.

Abstract: An architecture to provision one-stop parking, charging, storage, and/or maintenance facilities and/or functionalities for drone equipment. A method can comprise identifying a drone entering a defined airspace monitored by the network equipment; in response to establishing a communication channel with the drone, receiving data representing a physical dimension associated with the drone; based on the physical dimension associated with the drone, allocating a space within a defined area to which the drone is to navigate and then cease moving; and sending, to the drone via the communication channel, notification data that notifies the drone to navigate to the space.

Abstract: Provided herein are systems and methods for screening desirable biological variants using a high-throughput integrated system. The integrated system may be configured to input a plurality of parameters from functional studies of biological variants under applied conditions, in conjunction with integrated libraries of biological variants, and filter the inputs to produce desirable biological variants based on an input performance requirement. The system may output optimized strains, molecules, or novel molecules expected to have a desirable functional characteristic. Accordingly, the methods and systems disclosed herein enable multi-parametric studies of biological diversity and conditional diversity in systems biology.

Abstract: A method of preparing an antibody therapeutic is provided comprising: (a) providing a dissociated cell sample from at least one solid tumor sample obtained from a patient; (b) loading the dissociated cell sample into a microfluidic device having a flow region and at least one isolation region fluidically connected to the flow region; (c) moving at least one B cell from the dissociated cell sample into at least one isolation region in the microfluidic device, thereby obtaining at least one isolated B cell; and (d) using the microfluidic device to identify at least one B cell that produces antibodies capable of binding to cancer cells. The cancer cells can be the patient's own cancer cells. Also provided are methods of treating patients, methods of labeling or detecting cancer, engineered T or NK cells comprising antibodies or fragments thereof, and engineered antibody constructs.

Abstract: An extrusion process for creating a roof ditch molding including forming a main body from a plastic material in a first stage extrusion, conveying the main body through a stacked array of die plates and into a first stage cooling tank, and communicating the main body from an outlet of the first stage cooling tank to a second stage extruder with crosshead die for applying a skim film bonding layer to the main body. Additional steps include applying a decorative layer over the skim bonding layer, communicating the main body to a third stage extruder with cross head die for applying wing portions in partially overlapping fashion along opposite side edges of the decorative layer and drawing the completed ditch molding through a second stage cooling tank prior to conducting one or more finishing operations.

Abstract: The disclosure provides systems, devices, and associated methods for mitigating traumatic brain injury, injury to an ocular structure, or injury to the inner ear of a subject by applying pressure to one or more neck veins before and during an injurious event.

Abstract: A ruggedized adjustable mounting system is described for adjustably coupling and selectively locking a component supported in a fixture of the mount in a desired orientation. In some embodiments, the mounting system includes one or more kinematic couplings that support a fixture on a base and one or more adjustable couplings that are configured to adjust a separation distance between two opposing portions of the fixture and the base to selectively pivot the fixture about one or more axes of rotation.

Abstract: Embodiments of the invention are directed to a computer system that includes a memory electronically coupled to a processor system. The processor system is operable to perform processor system operations that include accessing a graph model representation of a computer network. The graph model is used to implement a resiliency-problem identification analysis that identifies a set of resiliency problems in the graph model. The graph model is used to apply a resiliency-problem solution analysis to a resiliency problem in the set of resiliency problems to generate a set of resiliency-problem solutions. Each resiliency-problem solution in the set of resiliency-problem solutions is ranked.