Patents by Inventor Kevin B. Teuscher

Kevin B. Teuscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WDR5 INHIBITORS AND MODULATORS
    Publication number: 20240262822
    Abstract: Isoquinolinone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
    Type: Application
    Filed: May 6, 2022
    Publication date: August 8, 2024
    Inventors: Taekyu Lee, Kevin B. Teuscher, Somenath Chowdhury, Jianhua Tian, Kenneth M. Meyers, Stephen W. Fesik
  • WDR5 inhibitors and modulators
    Patent number: 11999716
    Abstract: Isoquinolinone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: June 4, 2024
    Assignee: Vanderbilt University
    Inventors: Taekyu Lee, Joseph R. Alvarado, Jianhua Tian, Kenneth M. Meyers, Changho Han, Jonathan J. Mills, Kevin B. Teuscher, Shaun R. Stauffer, Stephen W. Fesik, Rocco D. Gogliotti
  • WDR5 INHIBITORS AND MODULATORS
    Publication number: 20230026466
    Abstract: Isoquinolmone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
    Type: Application
    Filed: November 8, 2020
    Publication date: January 26, 2023
    Inventors: Taekyu Lee, Kevin B. Teuscher, Jianhua Tian, Kenneth M. Meyers, Somenath Chowdhury, Stephen W. Fesik
  • WDR5 INHIBITORS AND MODULATORS
    Publication number: 20230012362
    Abstract: Isoquinolinone compounds and derivatives inhibit WDRS and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
    Type: Application
    Filed: October 24, 2019
    Publication date: January 12, 2023
    Inventors: Taekyu Lee, Joseph R. Alvarado, Jianhua Tian, Kenneth M. Meyers, Changho Han, Jonathan J. Mills, Kevin B. Teuscher, Shaun R. Stauffer, Stephen W. Fesik
  • WDR5 INHIBITORS AND MODULATORS
    Publication number: 20220242849
    Abstract: Quinazolin-4(3H)-one, 2,3-dihydroquinazolin-4(1H)-one, 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one, and 3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
    Type: Application
    Filed: June 4, 2020
    Publication date: August 4, 2022
    Inventors: Taekyu Lee, Changho Han, Jonathan J. Mills, Kevin B. Teuscher, Jianhua Tian, Kenneth M. Meyers, Somenath Chowdhury, Stephen W. Fesik