Patents by Inventor Kevin Blake

Kevin Blake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS OF BIFUNCTIONAL INHIBITORS OF TETRACYCLINE INACTIVATING ENZYMES AND METHODS OF USE THEREOF
    Publication number: 20260124217
    Abstract: Among the various aspects of the present disclosure is the provision of bifunctional inhibitors of tetracycline inactivating enzymes and methods of use thereof. Herein, compositions for inhibitors of tetracycline inactivating enzymes are described. Additionally, a method of treatment for multidrug resistant bacterial infections using inhibitors of tetracycline inactivating enzymes is disclosed.
    Type: Application
    Filed: March 6, 2025
    Publication date: May 7, 2026
    Applicant: Washington University
    Inventors: Timothy Wencewicz, Gautam Dantas, Niraj Tolia, Emily Williford, Caitlin DeAngelo, Kevin Blake, Hirdesh Kumar
  • COMPOSITIONS FOR OVERCOMING TETRACYCLINE ANTIBIOTIC RESISTANCE AND METHODS OF USE THEREOF
    Publication number: 20260060992
    Abstract: Compositions for overcoming tetracycline antibiotic resistance and methods of use thereof are provided. Compositions include at least one compound selected from Formula (I) and Formula (II) as disclosed herein. Methods of treating a subject having a bacterial infection include administering at least one compound selected from Formula (I) and Formula (II) as disclosed herein. In some embodiments, the composition further includes at least one tetracycline antibiotic.
    Type: Application
    Filed: August 28, 2025
    Publication date: March 5, 2026
    Applicants: Washington University, The United States of America, as Represented by the Secretary, Department of Health and Human Servic
    Inventors: Timothy Wencewicz, Gautam Dantas, Niraj Tolia, Emily Williford, Kevin Blake, Yao-Peng Xue, Wai Kwan Tang
  • TRACKING SYSTEMS WITH STANDARD TRANSMITTERS AND TAILORED CARRIERS
    Publication number: 20240407340
    Abstract: A tracking system includes a standardized transmitter and a customizable carrier for the transmitter. The customizable carrier may have a configuration that enables it to be attached to and carried by a subject for long durations of time, while enabling the standardized transmitter to be used with a variety of different types or configurations of subjects. Methods of assembling tracking systems and methods of tracking subjects are also disclosed.
    Type: Application
    Filed: June 12, 2024
    Publication date: December 12, 2024
    Inventors: Kevin Harcourt, Jerry Merritt, Kevin Blake
  • Lighted bicycle wheel hub assembly
    Patent number: 9296440
    Abstract: A bicycle wheel hub assembly having a number of light emitting diodes (LED's) that are powered by rotation of the wheel during use of the bicycle. The hub assembly includes a magnet and a coil that are both internal to the hub. The light emitting diodes are powered by current induced in the coil and controlled so as to preferably prevent illumination of discrete LED's when the respective LED's are directed toward a user during rotation of the hub. The LED's are supported by the hub and rotate with the hub during rotation of the wheel. In some embodiments, the LED's are attached to the hub at locations that are both laterally inboard and laterally outboard relative to a spoke flange of the hub assembly.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: March 29, 2016
    Assignee: Trek Bicycle Corporation
    Inventors: David Guzik, Kevin Blake, Tim Clavette
  • Lighted Bicycle Wheel Hub Assembly
    Publication number: 20130258691
    Abstract: A bicycle wheel hub assembly having a number of light emitting diodes (LED's) that are powered by rotation of the wheel during use of the bicycle. The hub assembly includes a magnet and a coil that are both internal to the hub. The light emitting diodes are powered by current induced in the coil and controlled so as to preferably prevent illumination of discrete LED's when the respective LED's are directed toward a user during rotation of the hub. The LED's are supported by the hub and rotate with the hub during rotation of the wheel. In some embodiments, the LED's are attached to the hub at locations that are both laterally inboard and laterally outboard relative to a spoke flange of the hub assembly.
    Type: Application
    Filed: May 28, 2013
    Publication date: October 3, 2013
    Inventors: David Guzik, Kevin Blake, Tim Clavette
  • Lighted bicycle wheel hub assembly
    Patent number: 8449157
    Abstract: A bicycle wheel hub assembly having a number of light emitting diodes (LED's) that are powered by rotation of the wheel during use of the bicycle. The hub assembly includes a magnet and a coil that are both internal to the hub. The light emitting diodes are powered by current induced in the coil and controlled so as to preferably prevent illumination of discrete LED's when the respective LED's are directed toward a user during rotation of the hub. The LED's are supported by the hub and rotate with the hub during rotation of the wheel. In some embodiments, the LED's are attached to the hub at locations that are both laterally inboard and laterally outboard relative to a spoke flange of the hub assembly.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: May 28, 2013
    Assignee: Trek Bicycle Corp.
    Inventors: David Guzik, Kevin Blake, Tim Clavette
  • Lighted Bicycle Wheel Hub Assembly
    Publication number: 20130044502
    Abstract: A bicycle wheel hub assembly having a number of light emitting diodes (LED's) that are powered by rotation of the wheel during use of the bicycle. The hub assembly includes a magnet and a coil that are both internal to the hub. The light emitting diodes are powered by current induced in the coil and controlled so as to preferably prevent illumination of discrete LED's when the respective LED's are directed toward a user during rotation of the hub. The LED's are supported by the hub and rotate with the hub during rotation of the wheel. In some embodiments, the LED's are attached to the hub at locations that are both laterally inboard and laterally outboard relative to a spoke flange of the hub assembly.
    Type: Application
    Filed: August 16, 2011
    Publication date: February 21, 2013
    Inventors: David Guzik, Kevin Blake, Tim Clavette