Abstract: A thrombus retrieval device configured to restore blood flow in neurovasculature by removing thrombus in human patients experiencing ischemic stroke.

Abstract: An automatic test equipment (ATE) contactor adapter compatible with at least one test board. The contactor adapter includes a contactor adapter body having a first side and a second side. The contactor adapter body includes: 1) a first set of contact components disposed on the first side in an arrangement to contact conductive pads of the at least one test board; and 2) a second set of contact components disposed on the second side and coupled to the first set of contact points. The contactor adapter also includes an adapter interface disposed on the contactor adapter body. The adapter interface includes a third set of contact components coupled to the second set of contact components. The ATE contactor adapter is configured to convey signals between a device under test (DUT) and the at least one test board via the first, second, and third sets of contact components.

Abstract: An end effector for a surgical clip applier includes an elongate body, a clip revolver rotatably positioned within the body and providing an inner bore that defines a plurality of clip slots angularly spaced from each other about an inner surface of the inner bore, wherein a plurality of surgical clips are receivable within the plurality of clip slots in a nested helical array. First and second jaw members extend past a distal end of the body and aligned to receive a distal-most surgical clip of the plurality of surgical clips, wherein the clip revolver is rotatable to sequentially align each surgical clip with the first and second jaw members.

Abstract: Method for using a clot retrieval device for treating a clot in a blood vessel for use in the treatment of ischemic stroke to reperfuse an obstructed vessel.

Abstract: The invention provides humanized anti-human Tau(pS422) antibodies and methods of using the same.

Abstract: A catheter has an expansile tip that can be delivered in a constricted form. The increased tip diameter facilitates the aspiration and removal of large clot volumes by increasing the area of the catheter tip that applies aspiration to the clot. The tip comprises a support frame which can be cut from a metal or polymer tube, covered with a thin polymer sleeve 909 containing highly elastic properties. This construction provides good pushability and high compressive resistance. The cut pattern can contain axial connections of the support frame and ring members, which will provide a large level of axial support, lateral flexibility and hoop strength to withstand aspiration. The tip of the device can contain a section proximal of the highly flexible area that can expand to except clot. This potential to increase body diameter facilitates the retrieval of large volume clots while the construction of the catheter provides good column stiffness to avoid axial collapse and still maintain good flexibility.

Abstract: Various systems and methods for implementing an anti-collision mechanism are described herein. A system for a lead vehicle to provide a visible light communication (VLC) message to a trailing vehicle behind the lead vehicle includes a vehicle controller subsystem of the lead vehicle, to: receive from a sensor array interface, sensor data from a forward-facing sensor incorporated into the lead vehicle; determine, using a processor, from the sensor data that a hazard exists; initiate the application of brakes with a braking force; and initiate, via a light controller, a VLC message to the trailing vehicle, the VLC message including the braking force.

Abstract: A masking film includes an adhesion layer that includes a blend of hydrogenated styrene block copolymer and low density polyethylene. The adhesion layer has an outer adhesion surface configured to contact a substrate. The outer adhesion surface has an average surface roughness Ra of between 100 nm and 350 nm, and an average spacing between peaks Sm of between 20 ?m and 150 ?m. The masking film also includes a release layer on a side of the adhesion layer opposite the outer adhesion surface.

Abstract: A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24,49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24,49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Abstract: A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24,49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24,49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Abstract: An automatic test equipment (ATE) contactor adapter compatible with at least one test board. The contactor adapter includes a contactor adapter body having a first side and a second side. The contactor adapter body includes: 1) a first set of contact components disposed on the first side in an arrangement to contact conductive pads of the at least one test board; and 2) a second set of contact components disposed on the second side and coupled to the first set of contact points. The contactor adapter also includes an adapter interface disposed on the contactor adapter body. The adapter interface includes a third set of contact components coupled to the second set of contact components. The ATE contactor adapter is configured to convey signals between a device under test (DUT) and the at least one test board via the first, second, and third sets of contact components.

Abstract: Method for using a clot retrieval device for treating a clot in a blood vessel for use in the treatment of ischemic stroke to reperfuse an obstructed vessel.

Abstract: A clot retrieval device 1 for removing occlusive clot from a blood vessel, the device comprises an inner elongate body 3 having a collapsed delivery configuration and an expanded deployed configuration and an outer elongate body 2 at least partially overlying the inner elongate body 2. The outer elongate body 2 is expandable to a radial extent which is greater than the radial extent of the inner body 3 in the deployed configuration to define a clot reception space 11. The outer elongate body 2 comprises a distal end portion 24,49 and the inner elongate body 3 comprises a main body portion 10 and a distal portion which extends in the deployed configuration towards the outer elongate body 2 to a greater extent than the main body portion. The distal portion 10 of the inner elongate member 3 and the distal end portion 24,49 of the outer elongate body 2 together define a three dimensional protective structure to substantially prevent distal egress of clot or clot fragments from the device.

Abstract: A clot retrieval device for removing clot from a blood vessel, including a shaft extending between a proximal end and a distal end; a first expandable body coupled to the distal end of the shaft, the first expandable body comprising a plurality of scaffolding segments forming closed cells, wherein at least one of the clot scaffolding segments terminates in a distal apex free from connection to an adjacent closed cell; a second expandable body distal of the first expandable body and comprising a plurality of scaffolding segments forming closed cells; and at least one clot inlet mouth between the first and second expandable bodies and the distal apex through which clot may pass and enter the device.

Abstract: Methods and systems for using a clot retrieval device for treating a clot in a blood vessel for use in the treatment of ischemic stroke to achieve a clinically effective revascularization or perfusion rate.

Abstract: A clot retrieval device for removing clot from a blood vessel, including a shaft; a plurality of expandable bodies distal of the shaft, each expandable body comprising a plurality of scaffolding segments forming closed cells, wherein at least one of the clot scaffolding segments terminates in a distal apex free from connection to an adjacent closed cell; and a plurality of clot inlet mouths between expandable bodies through which clot may pass and enter the device.

Abstract: A clot retrieval device may include an elongate member and an expandable clot engaging element configured to extend across the clot in its expanded state. The expandable clot engaging element may include a first monolithic structure and a second monolithic structure. The first monolithic structure may encircle the second monolithic structure over at least a portion of its length. The second monolithic structure may include a proximal section, an intermediate section, and a distal section. The distal section may include an expansion.

Abstract: An end effector for a surgical clip applier includes an elongate body, a clip revolver rotatably positioned within the body and providing an inner bore that defines a plurality of clip slots angularly spaced from each other about an inner surface of the inner bore, wherein a plurality of surgical clips are receivable within the plurality of clip slots in a nested helical array. First and second jaw members extend past a distal end of the body and aligned to receive a distal-most surgical clip of the plurality of surgical clips, wherein the clip revolver is rotatable to sequentially align each surgical clip with the first and second jaw members.

Abstract: A reperfusion device for an occluded vessel. The device includes a framework of struts that form a porous body comprising a collapsed delivery configuration capable of being stored in a microcatheter and an expanded deployed configuration when delivered to an occlusion and distal of the microcatheter. The framework of struts is constructed from a material visible under fluoroscopy and capable of recovering its shape in the expanded deployed configuration once released from the collapsed delivery configuration in the microcatheter.

Abstract: The system includes a modulatable illumination source configured to illuminate a surface of a sample disposed on a sample stage, a detector configured to detect illumination emanating from a surface of the sample, illumination optics configured to direct illumination from the modulatable illumination source to the surface of the sample, collection optics configured to direct illumination from the surface of the sample to the detector, and a modulation control system communicatively coupled to the modulatable illumination source, wherein the modulation control system is configured to modulate a drive current of the modulatable illumination source at a selected modulation frequency suitable for generating illumination having a selected coherence feature length. In addition, the present invention includes the time-sequential interleaving of outputs of multiple light sources to generate periodic pulse trains for use in multi-wavelength time-sequential optical metrology.