Patents by Inventor Kevin BUDDING

Kevin BUDDING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating paraproteinemic neuropathy with anti-C2 antibodies
    Patent number: 12708664
    Abstract: The present invention relates to a method of treating a paraproteinemic neuropathy in a subject by administering to the subject an antagonist of the complement system. The antagonist inhibits the complement system upstream of complement factor C5. More specifically, the antagonist may be an antibody or an antigen-binding fragment thereof that blocks or inhibits the complement system by inhibiting the C2b domain of complement factor C2. The paraproteinemic neuropathies that may be treated include, in particular, multifocal motor neuropathy (MMN), chronic inflammatory demyelinating polyneuropathy (CIDP), and Guillain-Barre syndrome (GBS).
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: August 18, 2026
    Assignee: argenx BV
    Inventors: Christophe Blanchetot, Kevin Budding, Erik Hack, Karen Silence, Inge Van De Walle, Ludo Van Der Pol, Peter Boross
  • ANTAGONISTS OF THE COMPLEMENT SYSTEM FOR USE IN METHODS OF TREATING PARAPROTEINEMIC NEUROPATHIES
    Publication number: 20250066460
    Abstract: The present invention relates to a method of treating a paraproteinemic neuropathy in a subject by administering to the subject an antagonist of the complement system. The antagonist inhibits the complement system upstream of complement factor C5. More specifically, the antagonist may be an antibody or an antigen-binding fragment thereof that blocks or inhibits the complement system by inhibiting the C2b domain of complement factor C2. The paraproteinemic neuropathies that may be treated include, in particular, multifocal motor neuropathy (MMN), chronic inflammatory demyelinating polyneuropathy (CIDP), and Guillain-Barre syndrome (GBS).
    Type: Application
    Filed: May 21, 2020
    Publication date: February 27, 2025
    Inventors: Christophe BLANCHETOT, Kevin BUDDING, Erik HACK, Karen SILENCE, Inge VAN DE WALLE, Ludo VAN DER POL, Peter BOROSS