Patents by Inventor Kevin C. Kain

Kevin C. Kain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Angiopoietin-based interventions for treating cerebral malaria
    Patent number: 10525106
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: January 7, 2020
    Assignees: Regeneron Pharmaceuticals, Inc., University Health Network
    Inventors: Lisa Arleen Purcell, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-Based Interventions for Treating Cerebral Malaria
    Publication number: 20190175699
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 13, 2019
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-based interventions for treating cerebral malaria
    Patent number: 10251938
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: April 9, 2019
    Assignees: Regeneron Pharmaceuticals, Inc., University Health Network
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-Based Interventions for Treating Cerebral Malaria
    Publication number: 20180228870
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Application
    Filed: April 10, 2018
    Publication date: August 16, 2018
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-based interventions for treating cerebral malaria
    Patent number: 9968653
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: May 15, 2018
    Assignees: Regeneron Pharmaceuticals, Inc., University Health Network
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-Based Interventions for Treating Cerebral Malaria
    Publication number: 20170136090
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Application
    Filed: January 25, 2017
    Publication date: May 18, 2017
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • Angiopoietin-based interventions for treating cerebral malaria
    Patent number: 9592271
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: March 14, 2017
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • ANGIOPOIETIN-BASED INTERVENTIONS FOR TREATING CEREBRAL MALARIA
    Publication number: 20160045566
    Abstract: The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
    Type: Application
    Filed: October 31, 2014
    Publication date: February 18, 2016
    Inventors: Lisa Arleen Purcell Ngambo, Sarah J. Higgins, Kevin C. Kain
  • ANGIOPOIETIN-1 AND -2 BIOMARKERS FOR INFECTIOUS DISEASES THAT COMPROMISE ENDOTHELIAL INTEGRITY
    Publication number: 20110008804
    Abstract: The invention relates to a method of identifying a subject having, or at risk of developing, an infectious disease state wherein endothelial integrity is compromised comprising: (a) determining a test ANG-1 level in a sample from a subject; and (b) comparing the test ANG-1 level to a control level wherein lower test ANG-1 level compared to the control level is indicative of the subject developing said infectious disease state.
    Type: Application
    Filed: November 5, 2008
    Publication date: January 13, 2011
    Inventors: Kevin C. Kain, W. Conrad Liles, Fiona E. Lovegrove