Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.

Abstract: A work machine includes a chassis, a boom coupled to the chassis, and a work implement coupled to the boom and movable relative to the chassis. In system may further include dynamic payload weighing system configured to measure the payload weight on the work implement. The system may also include an electrohydraulic system controller in communication with the dynamic payload weighing system and an electrohydraulic control valve electrically coupled to the electrohydraulic system controller and moveable to a plurality of weight-specific valve positions based on the measured payload weight on the implement.

Abstract: A work machine that has a chassis, a payload section, a controller, a payload sensor in communication with the controller, and an orientation sensor that identifies the orientation of the work machine to the controller. The controller determines a center of gravity for the work machine considering a payload weight identified by the payload sensor and sends an alert when the location of the center of gravity and the orientation of the work machine create an unstable condition.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for augmenting neural networks with an external memory. One of the systems includes a memory interface subsystem that is configured to perform operations comprising determining a respective content-based weight for each of a plurality of locations in an external memory; determining a respective allocation weight for each of the plurality of locations in the external memory; determining a respective final writing weight for each of the plurality of locations in the external memory from the respective content-based weight for the location and the respective allocation weight for the location; and writing data defined by the write vector to the external memory in accordance with the final writing weights.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for augmenting neural networks with an external memory. One of the systems includes a memory interface subsystem that is configured to perform operations comprising determining a respective content-based weight for each of a plurality of locations in an external memory; determining a respective allocation weight for each of the plurality of locations in the external memory; determining a respective final writing weight for each of the plurality of locations in the external memory from the respective content-based weight for the location and the respective allocation weight for the location; and writing data defined by the write vector to the external memory in accordance with the final writing weights.

Abstract: Users of head-mounted displays (HMDs) often experience nausea and other symptoms often referred to a “virtual reality sickness.” Various health and biometric sensors are employed to gather baseline sensor measurements. The HMD or a device associated with it can then generate a range or threshold such that any future sensor measurements that fall outside of the range or cross the threshold suggest a health concern for the user of the HMD. The HMD can also be coupled to a microphone, and natural language processing (NLP) is employed to detect negative words or noises made by the user that could also suggest a health concern for the user. After detecting the health concern, the HMD can warn its user, can shut off certain functions, can communicate with an external device, or can trigger an alarm.

Abstract: A sound suppressing gun barrel incorporating a bullet channel having breachward and muzzleward ends; at least a first “U” channel positioned radially outwardly from the bullet channel, the at least first “U” channel having a web, having a gas receiving arm extending muzzlewardly from the web, and having first and second gas conveying arms extending muzzlewardly from opposite ends of the web; the sound suppressing gun barrel further having an inlet port opening the at least first “U” channel at a muzzleward end of the at least first “U” channel's first gas conveying arm, the inlet port communicating with the bullet channel; the sound suppressing gun barrel further having an outlet port further opening the at least first “U” channel, the outlet port being positioned at a muzzleward end of the at least first “U” channel's second gas conveying arm.

Abstract: A window assembly having a first sash and a second sash mounted to a window frame, the first and second sashes arranged along different vertical planes within the window frame to resemble the appearance of a double hung window. The window assembly further includes a hinge mechanism coupled to the window frame, the hinge mechanism operable to guide the first and second sashes away from the window frame to accommodate an outwardly swinging motion of the sashes in a similar fashion as a conventional awning window.

Abstract: Users of head-mounted displays (HMDs) often experience nausea and other symptoms often referred to a “virtual reality sickness.” Various health and biometric sensors are employed to gather baseline sensor measurements. The HMD or a device associated with it can then generate a range or threshold such that any future sensor measurements that fall outside of the range or cross the threshold suggest a health concern for the user of the HMD. The HMD can also be coupled to a microphone, and natural language processing (NLP) is employed to detect negative words or noises made by the user that could also suggest a health concern for the user. After detecting the health concern, the HMD can warn its user, can shut off certain functions, can communicate with an external device, or can trigger an alarm.

Abstract: A gun barrel for guiding a bullet along a longitudinal axis, the bullet having a diameter, the gun barrel having a circumferential series of lands, each land among the circumferential series of lands being radially displaced from the longitudinal axis a distance at least as great as one-half of the bullet's diameter, each land extending helically about the longitudinal axis; a plurality of sound reflection chambers, each sound reflection chambers among the plurality of sound reflection chambers being positioned between an adjacent pair of lands among the circumferential series of lands, each sound reflection chamber having a muzzle end, and each sound reflection chamber opening radially inwardly; and a plurality of sound reflection walls, each wall among the plurality of sound reflection walls closing one of the sound reflection chambers' muzzle ends.

Abstract: Embodiments disclosed herein relate to a foldable array of three-dimensional panels, which may include one or more functional electrical components. For instance, the three-dimensional multi-panel array may be reconfigured from a substantially planar configuration into a three-dimensional configuration.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for augmenting neural networks with an external memory. One of the systems includes a memory interface subsystem that is configured to perform operations comprising determining a respective content-based weight for each of a plurality of locations in an external memory; determining a respective allocation weight for each of the plurality of locations in the external memory; determining a respective final writing weight for each of the plurality of locations in the external memory from the respective content-based weight for the location and the respective allocation weight for the location; and writing data defined by the write vector to the external memory in accordance with the final writing weights.

Abstract: A window assembly having a first sash and a second sash mounted to a window frame, the first and second sashes arranged along different vertical planes within the window frame to resemble the appearance of a double hung window. The window assembly further includes a hinge mechanism coupled to the window frame and to the second sash, hinge mechanism operable to guide the second sash away from the first sash to accommodate an outwardly swinging motion of the second sash in a similar fashion as a conventional awning window. The first sash may be fixed relative to the window frame, or may alternatively be moveable upwardly or downwardly relative to the window frame.

Abstract: A gun barrel for guiding a bullet along a longitudinal axis, the bullet having a diameter, the gun barrel having a circumferential series of lands, each land among the circumferential series of lands being radially displaced from the longitudinal axis a distance at least as great as one-half of the bullet's diameter, each land extending helically about the longitudinal axis; a plurality of sound reflection chambers, each sound reflection chambers among the plurality of sound reflection chambers being positioned between an adjacent pair of lands among the circumferential series of lands, each sound reflection chamber having a muzzle end, and each sound reflection chamber opening radially inwardly; and a plurality of sound reflection walls, each wall among the plurality of sound reflection walls closing one of the sound reflection chambers' muzzle ends.

Abstract: A system includes a monitoring module, a congestion module, a modification module, and a communication module. The monitoring module monitors vehicles in a transportation network. The congestion module calculates a throughput parameter that is representative of a statistical measure of adherence to a movement plan by the vehicles. The modification module determines a confidence parameter representative of a probability that changing the original meet event does not reduce the throughput parameter. The modification module modifies the original meet event to an updated meet event when the confidence parameter exceeds a predetermined threshold. The communication module transmits the updated meet event to the yielding vehicle and/or the passing vehicle, for the yielding vehicle and/or the passing vehicle to receive the updated meet event from the communication module and change a speed of the yielding vehicle or the passing rail vehicle to arrive at the updated meet event.

Abstract: Embodiments disclosed herein relate to a foldable array of three-dimensional panels, which may include one or more functional electrical components. For instance, the three-dimensional multi-panel array may be reconfigured from a substantially planar configuration into a three-dimensional configuration.

Abstract: A system is provided that includes a control unit configured to be disposed on-board at least one of a first vehicle or a second vehicle. The control unit also is configured to receive an updated time of an event involving the first vehicle and the second vehicle traveling in a transportation network. The control unit also is configured to change a speed of said at least one of the first vehicle or the second vehicle in response to the updated time to arrive at the event. A method is provided that includes, at one of a first vehicle or a second vehicle, receiving an updated time of an event involving the first vehicle and the second vehicle in a transportation network. The method also includes changing a speed of said one of the first vehicle or the second vehicle in response to the updated tune to arrive at the event.

Abstract: A system includes a monitoring module, a congestion module, a modification module, and a communication module. The monitoring module monitors vehicles in a transportation network. The congestion module calculates a throughput parameter that is representative of a statistical measure of adherence to a movement plan by the vehicles. The modification module determines a confidence parameter representative of a probability that changing the original meet event does not reduce the throughput parameter. The modification module modifies the original meet event to an updated meet event when the confidence parameter exceeds a predetermined threshold. The communication module transmits the updated meet event to the yielding vehicle and/or the passing vehicle, for the yielding vehicle and/or the passing vehicle to receive the updated meet event from the communication module and change a speed of the yielding vehicle or the passing rail vehicle to arrive at the updated meet event.

Abstract: A system is provided that includes a control unit configured to be disposed on-board at least one of a first vehicle or a second vehicle. The control unit also is configured to receive an updated time of an event involving the first vehicle and the second vehicle traveling in a transportation network. The control unit also is configured to change a speed of said at least one of the first vehicle or the second vehicle in response to the updated time to arrive at the event. A method is provided that includes, at one of a first vehicle or a second vehicle, receiving an updated time of an event involving the first vehicle and the second vehicle in a transportation network. The method also includes changing a speed of said one of the first vehicle or the second vehicle in response to the updated tune to arrive at the event.

Abstract: An integrated source code control and work item tracking tool is capable of establishing a relationship between work definition and work implementation. Once established, a more holistic view of the development process can be attained, and specific tasks can be easily accomplished. Tasks that may be accomplished using an integrated source code control and work item tracking tool include: automated generation of a list of work items that are completed in a new build of the system; automated updates of work items that are included in a build so that the work item details reflect the build in which it became available; automated transitioning of work items through a workflow when their implementation is complete and when their implementation is available in a new build; validation that source code changes represent the implementation of work items that have been approved; and managing change in the source code system with a focus on what work items it represents rather than a focus on what files are affected.