Abstract: An attachment assembly (25) and a ground engaging assembly for releasable attachment with earthmoving equipment is disclosed. In at least one embodiment, the attachment assembly (25) comprises a first body (30) configured for being placed in affirmative engagement with a portion (32) of or in fixed relation with respect to an edge of or associated with the earthmoving equipment. The attachment assembly (25) comprises a second body (35) configured for being placed in affirmative engagement with a portion of the ground engaging tool (GET, 15C or 15).

Abstract: The disclosure is directed to an apparatus, system, and method for performing energy-resolved scatter imaging during radiation therapy upon a patient. The apparatus includes a radiation detector capable of resolving the energy of the scattered photons due to Compton scattering during radiation therapy. The radiation detector outputs a first signal when photon energy of the detected photons is within a first energy range and a second signal when photon energy of the detected photons is within a second energy range. The apparatus also includes an image controller configured to receive the first and second signal and obtain an energy-resolved scatter image data set. The energy-resolved scatter imaging improves the contrast and sensitivity for identification of different tissue types. Therefore, tumor tracking during radiation therapy and image guidance during radiotherapy are improved.

Abstract: Methods of improved monitoring, testing and/or culturing of ova and/or sperm for in vitro fertilization are described herein. Methods of improved monitoring, testing and/or culturing of embryos during ex vivo pre-implantation selection are also described. The ova, sperm or embryos may be derived from wild animals or zoo animals. The ova, sperm or embryos can be mammalian, such as human, bovine, porcine, ovine, caprine, equine, canine, feline, murine, or the like.

Abstract: A video game body suit for use when playing a video game. The video game body suit includes a torso covering, leg coverings, arm coverings, and a headset. Each of the components includes one or more feedback devices thereon, wherein the feedback device may include one or more of a vibration motor, a speaker, a temperature controlling device, and a scent-emitting device. The headset comprises a headband, an earpiece, and a microphone thereon for allowing the user to remotely communicate with other players. The body suit further includes a control circuit that includes a microprocessor and a transceiver capable of wirelessly communicating with a video game console and the various feedback devices. In this way, the video game body suit can provide feedback to the user corresponding to the events that occur within the game.

Abstract: This invention relates to compounds of formula (I), and a method for treating anthrax or inhibiting lethal factor by administrating a composition containing a compound of formula (I) and a pharmaceutically acceptable carrier. This invention further relates to the use of the compounds of formula (I) to treat other conditions related to an anthrax infection.

Abstract: The present invention relates to substituted benzimidazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

Abstract: The present invention encompasses compounds of Formula (I) and pharmaceutically acceptable salts or hydrates thereof. The compounds are inhibitors of granzyme B and are useful for treating autoimmune and chronic inflammatory diseases. Pharmaceutical compositions and methods of use are also included.

Abstract: This invention relates to compounds of formula (I), and a method for treating anthrax or inhibiting lethal factor by administrating a composition containing a compound of formula (I) and a pharmaceutically acceptable carrier. This invention further relates to the use of the compounds of formula (I) to treat other conditions related to an anthrax infection.

Abstract: A method for agglomerating fine particles, involves reacting urea, urea/formaldehyde condensate, a strong inorganic acid, preferably sulfuric acid, and at least one polyfunctional compound chosen from the group consisting of hydroxycarboxylic acids, dicarboxylic acids, and polyols (containing at least two hydroxy groups) in the presence of particles to be agglomerated to form a fine particle agglomerate. Optionally, molasses, p-toluene sulfonic acid, xylene sulfonic acid or resorcinol can be added to the binder solution.

Abstract: A combinatorial library comprises a plurality of ligand-bearing support units, where the ligand-bearing support units comprise (a) a solid carrier, (b) one or more ligands covalently bound to the solid carrier, and (c) one or more encoding metal salts impregnated on the support unit, where the distribution of the cations of the encoding metal salts provides a code for identifying the ligand or ligands that are attached to the support units, and the cations have been stabilized against dissolution by treatment with one or more anions that form insoluble or poorly soluble salts of the cations.

Abstract: Vancomycin analogs in which the vancosamine residue is substituted on the vancosamine nitrogen with aryl substituents such as dichlorobenzyoxybenzyl, on the C6 position with a polar substituent such as amino or substituted amino, and provided with functionality at the carboxyl such as amido derivatives, have improved activity against bacterial infection.

Abstract: A combinatorial library comprises a plurality of ligand-bearing support units, where the ligand-bearing support units comprise (a) a solid carrier, (b) one or more ligands covalently bound to the solid carrier, and (c) one or more encoding metal salts impregnated on the support unit, where the distribution of the cations of the encoding metal salts provides a code for identifying the ligand or ligands that are attached to the support units, and the cations have been stabilized against dissolution by treatment with one or more anions that form insoluble or poorly soluble salts of the cations.

Abstract: The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R14 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

Abstract: This invention relates to somatostatin agonist compounds which are potent with high selectivity toward the receptor subtype 2. Compounds of the formula: ##STR1## including pharmaceutically acceptable salts and hydrates thereof are disclosed. These compounds are useful in the treatment of diabetes, cancer, acromegaly, restenosis, depression, irritable bowel syndrome, pain and diabetic retinopathy. Many of the compounds are also orally active.

Abstract: Somatostatin agonist compounds of formula I are disclosed: ##STR1## including pharmaceutically acceptable salts and hydrates thereof These compounds are useful in the treatment of diabetes, cancer, acromegaly, restenosis, depression, irritable bowel syndrome and pain. The compounds are potent with high selectivity toward the receptor subtype 2.Pharmaceutical compositions and methods of treatment are also included.

Abstract: Novel Carboxy-peptidyl compounds of Formula I are found to be useful inhibitors of matrix metalloendoproteinase-mediated diseases including osteoarthritis, rheumatoid arthritis, septic arthritis, tumor invasion in certain cancers, periodontal disease, corneal ulceration, proteinuria, dystrophobic epidermolysis bullosa, coronary thrombosis associated with atherosclerotic plaque rupture, and aneurysmal aortic disease. The matrix metalloendoproteinases are a family of zinc-containing proteinases including but not limited to stromelysin, collagenase, and gelatinase, that are capable of degrading the major components of articular cartilage and basement membranes. The inhibitors claimed herein may also be useful in preventing the pathological sequelae following a traumatic injury that could lead to a permanent disability. These compounds may also have utility as a means for birth control by preventing ovulation or implantation.

Abstract: A disposable transportable reactor vessel can be prepared by modifying an eye-dropper pipette. A HDPE plug is inserted in one end of the pipette to permit selective passage of fluid while preventing resin flow. The pipette is looped into the shape of a u-tube and inserted into a holder such that the pipette is axially aligned with the holder to facilitate use in a robotic system.