Abstract: The present invention features a stretchable strain sensor for detecting minute amounts of strain or pressure. The stretchable strain sensor may comprise a first soft polymer layer, a wrinkled conductive layer disposed on the first soft polymer layer, and a second soft polymer layer disposed on the wrinkled conductive layer. Strain applied to the sensor may cause the wrinkled conductive layer to stretch and crack and send a signal based on resistance. Pressure applied to the sensor may cause the wrinkled conductive layer to deform and crack and send a signal based on resistance. The stretchable strain sensor may be capable of measuring contractions of a tissue, detecting fluid flowing through a microfluidic channel, and detecting whether a microfluidic valve is closed or not.

Abstract: Methods for providing diagnostic information using endocardial surface data for a patient's heart are described herein. In some embodiments, endocardial surface data for the left ventricle of a heart is received. The endocardial surface data represents the endocardial surface of the left ventricle at multiple times over a heartbeat and is obtained using a volumetric imaging application. A representation in prolate spheroidal coordinates of the endocardial surface of the left ventricle at least a portion of the multiple times is generated using the endocardial surface data. The prolate spheroidal coordinates include a longitudinal angular coordinate ?, a circumferential angular coordinate ?, and a coordinate ? as a function of longitudinal angular coordinate ? and circumferential angular coordinate ?. A measure that provides diagnostic information related to the left ventricle is computed based at least on part on the value of coordinate ?.