Patents by Inventor Kevin D. Holbrook
Kevin D. Holbrook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150328021Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: ApplicationFiled: May 16, 2014Publication date: November 19, 2015Inventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 8771337Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: March 3, 2010Date of Patent: July 8, 2014Assignee: SyneCor LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 8152843Abstract: Improved polymeric endoprostheses having reinforcement elements and methods of making the endoprostheses are disclosed. The devices disclosed exhibit improved overall compliance, selective regional compliance, and selective radial strength without varying the geometries of selected regions. Numerous other physical characteristics of the endoprostheses described may be selectively varied during manufacture. Some embodiments may include an erodible polymer and magnesium. Some embodiments may have one or more therapeutics incorporated into the endoprosthesis via a solvent in a supercritical state.Type: GrantFiled: June 26, 2008Date of Patent: April 10, 2012Assignee: SyneCor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 7857748Abstract: Methods of manufacture of endoprostheses comprising one or more photocurable materials are disclosed. The endoprostheses may comprise regions wherein the photocurable materials are selectively disposed about the endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Photolithographic masking material may be selectively disposed about an inflatable balloon and exposed to a radiation emitting catheter.Type: GrantFiled: October 19, 2006Date of Patent: December 28, 2010Assignee: Syne Cor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Publication number: 20100256734Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: ApplicationFiled: March 3, 2010Publication date: October 7, 2010Inventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 7704276Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: September 30, 2006Date of Patent: April 27, 2010Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Publication number: 20090096137Abstract: Improved polymeric endoprostheses and methods of manufacturing endoprostheses are disclosed herein. The endoprostheses may comprise one or more polymers wherein the polymer chains are substantially aligned circumferentially, and comprising increased radial strength and flexibility. An endoprosthesis according to the invention may comprise a smooth surface. Endoprostheses disclosed herein may be used in the treatment of strictures in lumens of the body. Alternatively, endoprostheses disclosed herein may be used as anchors to secure medical devices within lumens of the body. The endoprostheses disclosed herein may comprise one or more erodible polymer.Type: ApplicationFiled: September 2, 2008Publication date: April 16, 2009Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn
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Publication number: 20080275539Abstract: Improved polymeric endoprostheses and methods of making endoprostheses are disclosed. Said endoprostheses exhibit improved overall compliance, selective regional compliance, and selective radial strength without varying the geometries of selected regions. Numerous other physical characteristics of said endoprostheses may be selectively varied during manufacture. Some embodiments may comprise one or more erodible material. Some embodiments may comprise one or more therapeutics incorporated into said endoprosthesis via a solvent in a supercritical state.Type: ApplicationFiled: June 26, 2008Publication date: November 6, 2008Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 7163554Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: November 8, 2004Date of Patent: January 16, 2007Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 7141061Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.Type: GrantFiled: January 15, 2003Date of Patent: November 28, 2006Assignee: SyneCor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 6887266Abstract: Improved endoprostheses comprising a delivery configuration and a deployed configuration and methods of manufacture are disclosed. Some embodiments according to the invention comprise woven tubular structures and means for maintaining said structures in their expanded configurations. In one embodiment of the invention, locking elements disposed on one or more fibers maintain said endoprosthesis in its deployed configuration. In alternative embodiments, one or more axial members may maintain said endoprosthesis in its deployed configuration. In yet additional alternative embodiments, a chemical bond or thermocouple may maintain said endoprosthesis in its deployed configuration. Some embodiments according to the invention may comprise erodible material.Type: GrantFiled: January 15, 2003Date of Patent: May 3, 2005Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Publication number: 20040098100Abstract: Improved endoprostheses comprising a delivery configuration and a deployed configuration and methods of manufacture are disclosed. Some embodiments according to the invention comprise woven tubular structures and means for maintaining said structures in their expanded configurations. In one embodiment of the invention, locking elements disposed on one or more fibers maintain said endoprosthesis in its deployed configuration. In alternative embodiments, one or more axial members may maintain said endoprosthesis in its deployed configuration. In yet additional alternative embodiments, a chemical bond or thermocouple may maintain said endoprosthesis in its deployed configuration. Some embodiments according to the invention may comprise erodible material.Type: ApplicationFiled: January 15, 2003Publication date: May 20, 2004Inventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Publication number: 20040098090Abstract: Improved polymeric endoprostheses and methods of making endoprostheses are disclosed. Said endoprostheses exhibit improved overall compliance, selective regional compliance, and selective radial strength without varying the geometries of selected regions. Numerous other physical characteristics of said endoprostheses may be selectively varied during manufacture. Some embodiments may comprise one or more erodible material. Some embodiments may comprise one or more therapeutics incorporated into said endoprosthesis via a solvent in a supercritical state.Type: ApplicationFiled: January 15, 2003Publication date: May 20, 2004Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Publication number: 20040098110Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.Type: ApplicationFiled: January 15, 2003Publication date: May 20, 2004Inventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone