Abstract: The present disclosure is related to a treatment probe and method for treating dry eye. The treatment probe may include a thin stainless steel tip, a spacer to ensure proper contact and protect the skin of a patient, a sensor to provide temperature feedback to the power supply providing RF energy to the treatment probe. The treatment focuses on a patient's temple and periorbital area.

Abstract: The present disclosure is related to a treatment probe and method for treating dry eye. The treatment probe may include a thin stainless steel tip, a spacer to ensure proper contact and protect the skin of a patient, a sensor to provide temperature feedback to the power supply providing RF energy to the treatment probe. The treatment focuses on a patient's temple and periorbital area.

Abstract: The present invention is related to a radiofrequency treatment probe and method delivering radiofrequency for controlled heating of tissue within the vagina for the treatment of vaginal laxity. The treatment probe may include a curved, rounded disposable treatment tip that may be designed to accommodate vaginal anatomy. An electrode assembly may be coupled to the treatment tip, wherein the electrode coupled to the treatment tip may be configured to transfer radiofrequency energy through vaginal skin surface to the tissue. A temperature measuring feature may include or be coupled to the electrode assembly, wherein the electrode assembly may be configured to regulate and maintain a pre-determined skin temperature. A radiofrequency handle may be configured to connect to a disposable treatment tip. A connector may be configured to connect to the radiofrequency handle to a radiofrequency generator. A protective apparatus may be configured to protect the radiofrequency handle.

Abstract: The present disclosure is related to a treatment probe and method for treating dry eye. The treatment probe may include a thin stainless steel tip, a spacer to ensure proper contact and protect the skin of a patient, a sensor to provide temperature feedback to the power supply providing RF energy to the treatment probe. The treatment focuses on a patient's temple and periorbital area.

Abstract: The present invention is related to a treatment probe and method for treating fecal incontinence. The treatment probe may include a straight, rounded treatment tip designed to accommodate rectal anatomy, an electrode assembly coupled to the treatment tip, wherein the electrode coupled to the treatment tip is configured to transfer radiofrequency energy to specific rectal structures, a temperature measuring feature coupled to the electrode assembly, wherein the temperature measuring feature coupled to the electrode assembly is configured to monitor and regulate electrode and skin temperature, a radiofrequency handle configured to connect to the treatment tip, a connector configured to connect the radiofrequency handle to a radiofrequency generator, and a protective apparatus configured to protect the radiofrequency handle.

Abstract: The present invention is related to a radiofrequency treatment probe and method delivering radiofrequency for controlled heating of tissue within the vagina for the treatment of vaginal laxity. The treatment probe may include a curved, rounded disposable treatment tip that may be designed to accommodate vaginal anatomy. An electrode assembly may be coupled to the treatment tip, wherein the electrode coupled to the treatment tip may be configured to transfer radiofrequency energy through vaginal skin surface to the tissue. A temperature measuring feature may include or be coupled to the electrode assembly, wherein the electrode assembly may be configured to regulate and maintain a pre-determined skin temperature. A radiofrequency handle may be configured to connect to a disposable treatment tip. A connector may be configured to connect to the radiofrequency handle to a radiofrequency generator. A protective apparatus may be configured to protect the radiofrequency handle.

Abstract: The present invention is related to a treatment probe and method for treating overactive bladders. The treatment probe may include a curved, rounded treatment tip designed to accommodate vaginal and urethral anatomy, an electrode assembly coupled to the treatment tip, wherein the electrode coupled to the treatment tip is configured to transfer radiofrequency energy to specific vaginal and urethral structures, a temperature measuring feature coupled to the electrode assembly, wherein the temperature measuring feature coupled to the electrode assembly is configured to monitor and regulate electrode and skin temperature, a radiofrequency handle configured to connect to the treatment tip, a connector configured to connect the radiofrequency handle to a radiofrequency generator, and a protective apparatus configured to protect the radiofrequency handle.

Abstract: The present invention provides methods for decreasing the amount and/or biological activity of angiotensin II in an aortic valve in an animal. The methods of the invention include administering to the animal an amount of an angiotensin converting enzyme antagonist and/or an angiotensin II type 1 receptor antagonist, effective to decrease the amount and/or biological activity of angiotensin II in the aortic valve in the animal.

Abstract: A segmented tape shoe for pressing tape into place along a predetermined path on a contoured lay-down surface. The tape shoe includes a plurality of tape shoe segments independently held in a close widthwise array by a shoe body. Each of the tape shoe segments has a substantially uniform width and a longitudinal cross section that is transversely urgeable against the composite tape. In one embodiment, each of the tape shoe segments is independently urgeable by pneumatic pressure. In another embodiment, the tape shoe segments can have a resilient layer covered by a low-friction skin.