Patents by Inventor Kevin D. Williams

Kevin D. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10734558
    Abstract: Monolithic LED chips are disclosed comprising a plurality of active regions on a submount, wherein the submount comprises integral electrically conductive interconnect elements in electrical contact with the active regions and electrically connecting at least some of the active regions in series. The submount also comprises an integral insulator element electrically insulating at least some of the interconnect elements and active regions from other elements of the submount. The active regions are mounted in close proximity to one another to minimize the visibility of the space during operation. The LED chips can also comprise layers structures and compositions that allow improved reliability under high current operation.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: August 4, 2020
    Assignee: Cree Huizhou Solid State Lighting Company Limited
    Inventors: Bradley E Williams, Kevin W Haberern, Bennett D Langsdorf, Manuel L Breva
  • Publication number: 20200222556
    Abstract: The present invention relates to methods of preparing a therapeutic exosome using a protein newly-identified to be enriched on the surface of exosomes. Specifically, the present invention provides methods of using the proteins for affinity purification of exosomes. It also provides methods of localizing a therapeutic peptide on exosomes, and targeting exosomes to a specific organ, tissue or cell by using the proteins. The methods involve generation of surface-engineered exosomes that include one or more of the exosome proteins at higher density, or a variant or a fragment of the exosome protein.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 16, 2020
    Applicant: Codiak BioSciences, Inc.
    Inventors: Kevin P. DOOLEY, Rane A. HARRISON, Russell E. MCCONNELL, Ke XU, Damian J. HOUDE, Nikki ROSS, Sonya HAUPT, John D. KULMAN, Douglas E. WILLIAMS
  • Patent number: 10561740
    Abstract: The present invention relates to methods of preparing a therapeutic exosome using a protein newly-identified to be enriched on the surface of exosomes. Specifically, the present invention provides methods of using the proteins for affinity purification of exosomes. It also provides methods of localizing a therapeutic peptide on exosomes, and targeting exosomes to a specific organ, tissue or cell by using the proteins. The methods involve generation of surface-engineered exosomes that include one or more of the exosome proteins at higher density, or a variant or a fragment of the exosome protein.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: February 18, 2020
    Inventors: Kevin P. Dooley, Rane A. Harrison, Russell E. McConnell, Ke Xu, Damian J. Houde, Nikki Ross, Sonya Haupt, John D. Kulman, Douglas E. Williams
  • Publication number: 20190380702
    Abstract: A control handle for use with a suture device operable through an endoscope includes a grip attachment configured to be secured to an endoscope and a control housing operably secured to the grip attachment. A catheter housing is moveably disposed within the control housing and adapted to releasably secure the suture catheter such that translation of the catheter housing causes translation of the suture catheter. A lever is rotatably securable relative to the catheter housing such that rotation of the lever relative to the catheter housing causes the catheter housing to move relative to the control housing. A sliding tab is disposed relative to the lever such that movement of the sliding tab relative to the lever causes the suture catheter to translate relative to the control wire disposed within the suture catheter.
    Type: Application
    Filed: June 19, 2019
    Publication date: December 19, 2019
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: CHRISTOPHER R. DEUEL, SHAUN D. COMEE, KEVIN WINDHEUSER, TODD M. PFIZENMAIER, BRIANA J. MORETTI, STAN GILBERT, THOMAS JONES, ASHRITA RAGHURAM, ANDREW JONES, EVAN HUNTER WILLIAMS, BRIAN YOO
  • Publication number: 20190380562
    Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices, systems and methods to endoscopically suture or otherwise manipulate tissues, organs and/or structures within a body of a patient.
    Type: Application
    Filed: June 19, 2019
    Publication date: December 19, 2019
    Inventors: Christopher R. Deuel, Shaun D. Comee, Kevin Windheuser, Todd M. Pfizenmaier, Andrew Jones, Brian H. Yoo, Evan H. Williams
  • Publication number: 20190357934
    Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include a body extending along an axis and a distal cap positioned distally of the body and coupled to a shaft extending along the axis. The body and the distal cap may be movable relative to each other. An anchoring mechanism may be capable of engaging the body and the distal cap proximate a selected tissue for resection in the body lumen. A tissue capture device may be deployable from the tissue resection device such that a selected tissue for resection is securable by the tissue capture device. The tissue resection device may further include a tissue resecting device for resecting the selected tissue for resection.
    Type: Application
    Filed: May 22, 2019
    Publication date: November 28, 2019
    Inventors: Michael M. Borek, Micah Flock, Julianne Grainger, Christopher A. Olmeda, Katie Olmeda, Rachel M. Williams, Morgan Zhu, John B. Golden, Chris Jicka, Austin G. Johnson, Caleb A. Valdes, Serena Scott, Michael K. Ford, Kyle P. Moore, Janice Courtois, Prashanth Somasundaram, Ryan V. Wales, Scott E. Brechbiel, Rachael Campion, Tara A. Jarobski, Danny S. Lee, Alexander J. Burnham, Christopher K. Oto, Nicholas J. Mazzola, Kevin L. Bagley, Shaun D. Comee
  • Publication number: 20190198734
    Abstract: Monolithic LED chips are disclosed comprising a plurality of active regions on a submount, wherein the submount comprises integral electrically conductive interconnect elements in electrical contact with the active regions and electrically connecting at least some of the active regions in series. The submount also comprises an integral insulator element electrically insulating at least some of the interconnect elements and active regions from other elements of the submount. The active regions are mounted in close proximity to one another to minimize the visibility of the space during operation. The LED chips can also comprise layers structures and compositions that allow improved reliability under high current operation.
    Type: Application
    Filed: March 1, 2019
    Publication date: June 27, 2019
    Inventors: BRADLEY E. WILLIAMS, KEVIN W. HABERERN, BENNETT D. LANGSDORF, MANUEL L. BREVA
  • Publication number: 20190151456
    Abstract: The present invention relates to methods of preparing a therapeutic exosome using proteins newly identified to be enriched in the lumen of exosomes. Specifically, the present invention provides methods of localizing a therapeutic peptide or protein in exosomes. The methods involve generation of lumen-engineered exosomes that include one or more of the exosome proteins at higher concentrations, a modification or a fragment of the exosome protein, or a fusion protein of the exosome protein and a therapeutic or cargo protein.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 23, 2019
    Inventors: Russell E. McConnell, Kevin P. Dooley, Rane A. Harrison, Ke Xu, Damian J. Houde, Sonya Haupt, John D. Kulman, Douglas E. Williams, Madeleine Youniss
  • Publication number: 20080216456
    Abstract: A filter apparatus removably attachable to at least one of a door frame, a window frame, a screen, a wall, a door, and a window is provided. Such filter apparatus includes a filter member, manufactured from a first predetermined material and having a first predetermined size and a first predetermined shape, for filtering dust, debris, pollutants, insects, dirt, allergens, pollen, rain, and irritants. A frame member is manufactured from a second predetermined material and has a second predetermined size and a second predetermined shape. A mechanism is provided for operably connecting such filter member to such frame member. A fastening mechanism is provided for removably fastening such frame member to at least one of such door frame, such window frame, such screen, such wall, such door, and such window.
    Type: Application
    Filed: February 25, 2008
    Publication date: September 11, 2008
    Inventor: Kevin D. Williams
  • Patent number: 5591011
    Abstract: The oil sump and suction plenum of a hermetic compressor are in continuous fluid communication through an oil equalization port assembly. Additionally, communication is established between the oil sump and the suction plenum if pressure in the oil sump is greater than that in the suction plenum by more than a few pounds. Multiplexing is established through a port in the suction plenum.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: January 7, 1997
    Assignee: Carrier Corporation
    Inventors: Michael N. Mantooth, Kevin D. Williams, Bruce A. Fraser