Abstract: Methods and systems for co-locating journaling and data storage are provided. Separate journal and volume partitions may be maintained within each logical storage unit (e.g., Logical Unit Number (LUN)) of a distributed storage system. Journaling of metadata associated with write requests received from one or more clients may be distributed by identifying a destination logical storage unit to which data associated with a given write request is to be stored and causing the data and metadata to be persisted to disk by journaling the metadata and the data to respective portions of an active log within the journal partition of the destination logical storage unit. By using the same logical storage unit for both journaling of write requests and writing the data associated with such write requests, the bottleneck due to there being only a single device or storage unit handling all metadata for all write requests can be avoided.

Abstract: Techniques are provided for multi-tier write allocation. A storage system may store data within a multi-tier storage environment comprising a first storage tier (e.g., storage devices maintained by the storage system), a second storage tier (e.g., a remote object store provided by a third party storage provider), and/or other storage tiers. A determination is made that data (e.g., data of a write request received by the storage system) is to be stored within the second storage tier. The data is stored into a staging area of the first storage tier. A second storage tier location identifier, for referencing the data according to a format utilized by the second storage tier, is assigned to the data and provided to a file system hosting the data. The data is then destaged from the staging area into the second storage tier, such as within an object stored within the remote object store.

Abstract: This disclosure relates generally to roll stabilization and related apparatuses.

Abstract: Microfluidic channels networks and systems are provided. One network includes a first fluid channel having a first depth dimension; at least a second channel intersecting the first channel at a first intersection; at least a third channel in fluid communication with the first intersection, at least one of the first intersection and the third channel having a depth dimension that is greater than the first depth dimension. Also provided is a flow control system for directing fluids in the network. Systems are additionally provided for flowing disrupted particles into a droplet formation junction, whereby a portion of the disrupted particles or the contents thereof are encapsulated into one or more droplets. Further provided is a method for controlling filling of a microfluidic network by controlling passive valving microfluidic channel network features.

Abstract: A turbine engine includes an engine core extending along an engine centerline and includes a compressor section, a combustor, and a turbine section in serial flow arrangement. A temperature sensor is provided within the engine and configured to detect a gas temperature within the engine core. A set of blades is circumferentially arranged in the turbine section. A blade in the set of blades includes an outer wall bounding an interior, a cooling conduit within the interior, and a plurality of film holes fluidly coupled to the cooling conduit.

Abstract: Techniques for conversational-based searching are described. A system may receive a first spoken user input, and may determine that the first spoken user input corresponds to a request for information associated with an entity. The system may retrieve item results corresponding to the entity. The system may determine a suggested user input based on the retrieved item results, and may determine output data corresponding to the suggested user input. The system may send output data to a user device, where the output data includes the item results and the suggested user input. The system may receive a second spoken user input, and may determine that the second spoken user input corresponds to the suggested user input. In response, the system may send the previously determined output data to the device.

Abstract: Systems and methods for performing a zero-copy volume move between nodes of a distributed storage system are provided. In one example, an approach for performing a zero-copy volume move is proposed in which volume data may be maintained in place within a storage pod and need not be copied to move a given volume between the source node and the destination node. In one embodiment, metadata (e.g., a top-most physical volume block number (PVBN) of a node tree representing the volume at issue) of a write-anywhere file system is copied from the source node to the destination node. Since the storage pod is associated with a global PVBN space that is visible and accessible to all nodes of the distributed storage system, as a result of copying the top-mode PVBN of the volume to the destination node, anything below the top-most PVBN will automatically be visible to the destination node.

Abstract: A tubing assembly for use with a patient interface device includes a manifold portion structured to be coupled to a conduit carrying a flow of breathing gas and a number of tubular portions. Each tubular portion extends from the manifold portion to a distal end which is structured to be coupled to the patient interface device. Each tubular portion is structured to communicate the flow of breathing gas from the manifold portion to the patient interface device. Each tubular portion comprises an adjustment element which provides for a characteristic of the tubular portion to be selectively varied.

Abstract: Provided are defined bacterial compositions for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for populating the gastrointestinal tract of a subject. Provided also are bacterial formulations for oral or gastric administration to a mammalian subject in an effective amount for prevention or treatment of a gastrointestinal disease, disorder or condition.

Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for their preparation and separations devices containing the chromatographic materials. The chromatographic materials of the invention have controlled porosity and comprise a chromatographic core material and one or more layers of chromatographic surface materials which each independently provide an average pore diameter, an average pore volume, or a specific surface area such that the combined layers form a chromatographic material having a predetermined or desired pattern of porosity from the core material to the outermost surface. The materials are useful for HPLC separations, normal-phase separations, reversed-phase separations, chiral separations, HILIC separations, SFC separations, affinity separations, perfusive separations, partially perfusive separations, and SEC separations.

Abstract: Techniques are provided for failing over an aggregate from one file system instance to a different file system instance of a distributed scale-out storage system. The aggregate may be stored within distributed storage that is accessible to a plurality of file system instances of the distributed scale-out storage system. When the aggregate is failed over from a first file system instance to a second file system instance, the first file system instance may still have a valid read lease that allows the first file system instance to serve client I/O, directed to the aggregate, using a cache. In order to prevent the first file system instance from serving stale data from the cache before the read lease expires, state machines and a set of control data are used to ensure that the second file system instance attaches to the aggregate only after the read lease has expired.

Abstract: A method, system and computer program product for improving discernment between qubit states in superconducting quantum computers. Channels are calibrated to train the kernel to contain the correct calibration data (“kernel states”). After calibrating a channel, testing is performed in which quantum operations are performed on qubits at the same time in adjacent channels, including the recently calibrated channel, to determine if the kernel response differs from the expected kernel response, where the expected kernel response is based on the kernel states of the trained kernel of the recently calibrated channel, beyond a threshold value. If such a situation occurs, then the phase of the signal for the recently calibrated channel is shifted and the process of recalibrating the channel (using the phase shifted signal) and testing is repeated until the difference between the kernel response and the expected kernel response is not beyond the threshold value.

Abstract: Traditionally, meetings are widely utilized in business and personal communications, whether in-person and/or virtual. Organizing such meetings typically involves multiple exchanges of content and messages between users before, during, and after the meeting. In some cases, meetings may occur impromptu and may result in inefficient and unproductive collaboration. A collaboration object configured to enable users to dynamically collaborate before, during, and after a meeting is provided. In aspects, the collaboration object links content generated before, during, and after the meeting in a single location and provides functionality for concurrent multi-user interaction and synchronization of the content across applications. The collaboration object may be available from a variety of application platforms, enabling and persisting real-time editing and collaboration before, during and after the meeting.

Abstract: Techniques are provided for multi-tier write allocation. A storage system may store data within a multi-tier storage environment comprising a first storage tier (e.g., storage devices maintained by the storage system), a second storage tier (e.g., a remote object store provided by a third party storage provider), and/or other storage tiers. A determination is made that data (e.g., data of a write request received by the storage system) is to be stored within the second storage tier. The data is stored into a staging area of the first storage tier. A second storage tier location identifier, for referencing the data according to a format utilized by the second storage tier, is assigned to the data and provided to a file system hosting the data. The data is then destaged from the staging area into the second storage tier, such as within an object stored within the remote object store.

Abstract: A dental appliance occlusal element includes a lower surface comprising one or more features configured to interface with a pick-and-place robot to cause the dental appliance occlusal element to be inserted into a hollow feature of a dental appliance. The dental appliance occlusal element further includes an upper surface configured to be disposed adjacent a distal inner surface of the hollow feature. The dental appliance occlusal element further includes one or more side surfaces configured to be disposed against one or more side inner surfaces of the hollow feature.

Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: The current invention provides a novel method to synthesize a mono-disperse non-porous polymer particles with a unique gradient composition from the core to the shell. In particular, the present invention offers the flexibility to design the chemical and physical properties of different sections of the particle. This flexibility allows for significant latitude in the design of particles for analyzing a large variety of samples in different fields—through using these particles in different chromatography techniques including, but not limited to, ion exchange HPLC (e.g., bio-separation at different modes), reversed-phase HPLC, narrow bore and capillary HPLC, hydrophilic/hydrophobic interaction liquid chromatography, capillary electrochromatography separation, and two dimensional liquid chromatography.

Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.

Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: Techniques are provided for storage tier verification checks. A determination is made that a mount operation of an aggregate of a set of volumes stored within a multi-tier storage environment has completed. A first metafile and a second metafile are maintained to track information related to the storage of objects of a volume of the aggregate within a remote object store that is a tier of the multi-tier storage environment. A distributed verification is performed between the first metafile and the second metafile to identify an inconsistency. Accordingly, the first metafile and the second metafile are reconciled to address the inconsistency so that storage information within the first metafile and the second metafile are consistent.