Patents by Inventor Kevin David Howe

Kevin David Howe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
    Patent number: 12227565
    Abstract: This disclosure features methods and compositions for treating inflammatory disorders or conditions that arise in a tissue originating from the endoderm using an immune modulator.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 18, 2025
    Assignee: Biora Therapeutics, Inc.
    Inventors: Mitchell Lawrence Jones, Christopher Loren Wahl, Sharat Singh, Kevin David Howe, Arana Perera
  • Treatment of a disease of the gastrointestinal tract with a JAK or other kinase inhibitor
    Patent number: 12171764
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a JAK or other kinase inhibitor.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: December 24, 2024
    Assignee: BIORA THERAPEUTICS, INC.
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera
  • AQUEOUS FORMULATIONS OF TOFACITINIB AND TOFACITINIB SALTS
    Publication number: 20240299295
    Abstract: Aqueous formulations containing active pharmaceutical ingredient and cyclodextrin and their method of preparation and their uses are provided herein
    Type: Application
    Filed: September 9, 2022
    Publication date: September 12, 2024
    Inventors: Thotsaphon VONGASAVARIT, Aruna PERERA, Kevin David HOWE
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR
    Publication number: 20230312700
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a TNF-alpha inhibitor.
    Type: Application
    Filed: June 19, 2019
    Publication date: October 5, 2023
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera
  • INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT
    Publication number: 20230149315
    Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.
    Type: Application
    Filed: December 11, 2020
    Publication date: May 18, 2023
    Inventors: Jeffrey A. SHIMIZU, Mitchell Lawrence JONES, Mark Sasha DRLIK, Iman NIKNIA, Nathan John MULLER, Tuyen NGUYEN, Christopher Loren WAHL, Edward MUDGE, Nicholas Mark SALT, Nia Eleri STEVENS, Stuart Robert ABERCROMBIE, Christopher Ian BUNCE, Ryan Elliott JONES, Kevin David HOWE, Pejman RAHIMIAN, Nelson QUINTANA
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOMODULATOR
    Publication number: 20230041197
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunomodulator.
    Type: Application
    Filed: June 19, 2019
    Publication date: February 9, 2023
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN INTEGRIN INHIBITOR
    Publication number: 20230033021
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an integrin inhibitor. In particular, the disclosure features the topical treatment of sections and subsections of the gastrointestinal tract by integrin inhibitors (like vedolizumab) using an ingestible device that can detect its whereabouts in the Gl tract by using reflectance and which is programmed to release the drugs at a given site or proximal thereto, to treat gastrointestinal inflammatory diseases. The device has hardware storage devices with instructions on board to determine the location and release the formulations. Combination therapies are claimed as well in which the integrin inhibitor is added systemically and another agent (e.g. JAK inhibitor, TNF-alpha inhibitor or IL-12/IL-23 inhibitor) is added topically by means of the ingestible device. The topical administration is said to reduce the side effects associated with systemic treatment.
    Type: Application
    Filed: June 20, 2019
    Publication date: February 2, 2023
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera, Barbara Potts
  • TREATMENT OF A DISEASE OR CONDITION IN A TISSUE ORGINATING FROM THE ENDODERM
    Publication number: 20230009902
    Abstract: This disclosure features methods and compositions for treating inflammatory disorders or conditions that arise in a tissue originating from the endoderm using an immune modulator.
    Type: Application
    Filed: June 19, 2019
    Publication date: January 12, 2023
    Inventors: Mitchell Lawrence Jones, Christopher Loren Wahl, Sharat Singh, Kevin David Howe, Arana Perera
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A JAK OR OTHER KINASE INHIBITOR
    Publication number: 20220257600
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a JAK or other kinase inhibitor.
    Type: Application
    Filed: June 19, 2019
    Publication date: August 18, 2022
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR
    Publication number: 20220135666
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a S1P modulator.
    Type: Application
    Filed: December 13, 2018
    Publication date: May 5, 2022
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Aruna Perera
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IL-12/IL-23 INHIBITOR
    Publication number: 20210363233
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an IL-12/IL-23 inhibitor.
    Type: Application
    Filed: June 19, 2019
    Publication date: November 25, 2021
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Arana Perera
  • TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A PDE4 INHIBITOR
    Publication number: 20210031012
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a PDE4 inhibitor.
    Type: Application
    Filed: January 24, 2019
    Publication date: February 4, 2021
    Inventors: Mitchell Lawrence Jones, Sharat Singh, Christopher Loren Wahl, Harry Stylli, Kevin David Howe, Aruna Perera