Abstract: A system and method for determining an arrhythmia risk are provided and include memory to store specific executable instructions and a machine learning (ML) model trained to predict an arrhythmia with a characteristic of interest (COI) that exhibits a non-physiologic behavior. One or more processors are configured to execute the specific executable instructions to obtain CA signals collected by an implantable medical device (IMD), wherein the COI exhibits a physiologic behavior and apply the ML model to the CA signals to identify a risk factor that a patient will experience the arrhythmia at a future point in time even though the COI in the CA signals, exhibits a physiologic behavior.

Abstract: A conduit contactor for conducting chemical reactions or chemical extractions between immiscible liquids includes a conduit having a hollow interior, a first open end, and a second open end opposite the first open end; a separator in fluid communication with and proximate the second open end; and a plurality of fibers disposed within the conduit. A total surface area of the fibers per volume of the hollow interior of the conduit is from 100 cm2/cm3 to 490 cm2/cm3.

Abstract: A self propelled power trowel for finishing a concrete surface is equipped with reversible rotors to allow an operator to reverse the direction of rotation of rotor blades. The trowel includes a rigid frame adapted for operation over a concrete surface, a pair of rotor assemblies having rotor blades tiltably connected to the rigid frame for frictionally contacting the concrete surface and supporting the rigid frame thereabove, a prime mover mounted to the rigid frame and operatively coupled to drive the rotor blades of the rotor assemblies in opposite rotational directions. Synchronous or hydraulic motors are configured for causing, responsive to manual controls, reversal of the direction of rotation of the rotor blades.

Abstract: A conduit contactor for conducting chemical reactions or chemical extractions between immiscible liquids includes a conduit having a hollow interior, a first open end, and a second open end opposite the first open end; a separator in fluid communication with and proximate the second open end; and a plurality of fibers disposed within the conduit. A total surface area of the fibers per volume of the hollow interior of the conduit is from 100 cm2/cm3 to 490 cm2/cm3.

Abstract: The present disclosure is directed to systems and methods for high flame temperature oxy-combustion that enables the capture of CO2 cost effectively. One part of the presently disclosed subject matter comprises an annular shroud burner which utilizes a supply of undiluted oxygen and minimal flue gas recycle to generate a high flame temperature to maximize efficiency. The annular shroud burner may deliver oxygen into a combustion zone where mixing of the oxygen and a stream of fuel occurs. Flue gas recycled from the exit of the combustion system serves the dual purpose of conveying the coal into the reaction zone, as well as providing local cooling and protection from high incident heat fluxes through the novel shroud cooling design. The annular shroud burner may be configured to produce an axial jet flame that controls the rate of mixing of oxygen and fuel, thereby extending the heat release. Oxygen and coal may be mixed in a ratio such that peak flame temperatures exceed 4,500° F. (2,482° C.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A temperature sensing system for a resistive welding process for a tube performs repeatable temperature measurement using a camera to detect multiple distinct visible light wavelengths even as the ambient environment in the view path changes. Sensed colors in a field of view in the vicinity of a weld are output to a computing element that calculates a corresponding temperature and alerts an operator when the sensed color exceeds a preset color range.

Abstract: Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein.

Abstract: Methods for improving the antibacterial characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant comprising a silicon nitride ceramic material may be subjected to a surface roughening treatment so as to increase a surface roughness of at least a portion of the biomedical implant to a roughness profile having an arithmetic average of at least about 500 nm Ra. In some implementations, a coating may be applied to a biomedical implant. Such a coating may comprise a silicon nitride ceramic material, and may be applied instead of, or in addition to, the surface roughening treatment process.

Abstract: The present disclosure is directed to systems and methods for high flame temperature oxy-combustion that enables the capture of CO2 cost effectively. One part of the presently disclosed subject matter comprises an annular shroud burner which utilizes a supply of undiluted oxygen and minimal flue gas recycle to generate a high flame temperature to maximize efficiency. The annular shroud burner may deliver oxygen into a combustion zone where mixing of the oxygen and a stream of fuel occurs. Flue gas recycled from the exit of the combustion system serves the dual purpose of conveying the coal into the reaction zone, as well as providing local cooling and protection from high incident heat fluxes through the novel shroud cooling design. The annular shroud burner may be configured to produce an axial jet flame that controls the rate of mixing of oxygen and fuel, thereby extending the heat release. Oxygen and coal may be mixed in a ratio such that peak flame temperatures exceed 4,500° F. (2,482° C.

Abstract: Methods for improving the antibacterial characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant comprising a silicon nitride ceramic material may be subjected to a surface roughening treatment so as to increase a surface roughness of at least a portion of the biomedical implant to a roughness profile having an arithmetic average of at least about 500 nm Ra. In some implementations, a coating may be applied to a biomedical implant. Such a coating may comprise a silicon nitride ceramic material, and may be applied instead of, or in addition to, the surface roughening treatment process.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A self propelled power trowel for finishing a concrete surface is equipped with reversible rotors to allow an operator to reverse the direction of rotation of rotor blades. The trowel includes a rigid frame adapted for operation over a concrete surface, a pair of rotor assemblies having rotor blades tiltably connected to the rigid frame for frictionally contacting the concrete surface and supporting the rigid frame thereabove, a prime mover mounted to the rigid frame and operatively coupled to drive the rotor blades of the rotor assemblies in opposite rotational directions. Synchronous or hydraulic motors are configured for causing, responsive to manual controls, reversal of the direction of rotation of the rotor blades.

Abstract: Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein.

Abstract: A hybrid drive train for a self propelled power trowel includes a frame having a centerline from front to rear, an engine-generator set, a pair of rotors with trowel blades tiltably connected to the frame and positioned to support the frame above a concrete surface being finished, electric motors for driving the rotors, means for tilting each rotor toward and away from the centerline, and means for tilting a rotor fore and aft, parallel to the centerline. A rectifier and inverter in series at the engine-generator output allows engine speed to be regulated by a capacitor bank, and usage of highly efficient brushless AC synchronous motors to drive the rotors. A rechargeable battery may be connected in parallel with the capacitor bank.

Abstract: The invention provides a pigment composition comprising anthocyanic vacuolar inclusions or “AVIs” from a plant, and an acceptable carrier. The invention also provides methods for colouring products with the pigment composition, and products comprising the pigment composition or AVIs.

Abstract: Disclosed herein is glutathione in conjunction with an isoselenazol or isothiazol derivative, e.g., ebselen or ebsulfur derivative, to treat diabetes, lupus, or other chronic inflammatory disease. The glutathione is preferably provided in a rapid release oral formulation that presents the glutathione for absorption in the first part of the ileum. The isoselenazol or isothiazol derivative is preferably provided in a delayed release formulation to avoid overlapping high enteric concentration. These may be provided within the same unit dosage form.

Abstract: Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A Christmas tree disposal casing, having an upper end and a lower end, and a first panel and a second panel that each have an inner edge, an outer edge, an upper edge, and a lower edge. The casing has a flat configuration and also has a sleeve configuration for encasing a tree therein when the first panel is joined to the second panel at or near their outer edges. An expansion panel is affixed near and extends between the inner edges. The inner edges are selectively joined directly together along an expansion seam. When the expansion seam is opened, the expansion panel provides additional circumference to the casing for holding larger trees. The outer edge of the first panel is selectively joined to a secondary zipper edge on the second panel, located inwardly of the outer edge of the second panel, to reduce the circumference of the casing.