Abstract: A fitting that provides a sealed connection can include a face seal surface defining an annular groove having an outer wall that extends inward from the face seal surface, a floor and an inner ramp wall that extends away from the floor toward the face seal surface. The inner ramp wall can be disposed at an acute angle relative to the floor. In some applications, this angle can be about 64° to about 68°. An O-ring can be disposed in the annular groove and under tension due to being stretched over the inner ramp wall. The O-ring can exert a force radially inward toward the longitudinal axis along the inner ramp wall to thereby improve retention of the O-ring in the annular groove.

Abstract: A system and method for determining an arrhythmia risk are provided and include memory to store specific executable instructions and a machine learning (ML) model trained to predict an arrhythmia with a characteristic of interest (COI) that exhibits a non-physiologic behavior. One or more processors are configured to execute the specific executable instructions to obtain CA signals collected by an implantable medical device (IMD), wherein the COI exhibits a physiologic behavior and apply the ML model to the CA signals to identify a risk factor that a patient will experience the arrhythmia at a future point in time even though the COI in the CA signals, exhibits a physiologic behavior.

Abstract: Embodiments reduce burden associated with analyzing EGM segments obtained from an IMD that monitors for arrhythmic episodes. Respective EGM data and respective classification data is obtained for each arrhythmic episode detected by the IMD during a period of time. A representative R-R interval or HR for each of the arrhythmic episodes is determine by the IMD, wherein a manner for determining the representative R-R interval or HR depends on the type of the arrhythmic episode, such that for at least two different types of arrhythmic episodes the manners differ. An external system(ES) obtains data from the IMD, directly or indirectly, and selects arrhythmic episode(s) for which corresponding EGM segments are to be displayed for each type of arrhythmic episode, wherein the selecting is performed based on the representative R-R intervals or HRs determined by the IMD for the arrhythmic episodes. Additional and alternative embodiments are also described herein.

Abstract: Embodiments described herein can reduce a burden associated with analyzing EGM segments obtained from an IMD that monitors for arrhythmic episodes. Respective EGM data and respective classification data is obtained for each arrhythmic episode detected by the IMD during a period of time. A representative R-R interval or HR for each of the arrhythmic episodes is also obtained, wherein a manner for determining the representative R-R interval or HR depends on the type of the arrhythmic episode, such that for at least two different types of arrhythmic episodes the manners differ. One or more arrhythmic episodes is/are selected for which corresponding EGM segments are to be displayed for each type of arrhythmic episode, wherein the selecting is performed based on the representative R-R intervals or HRs that are determined for the plurality of arrhythmic episodes. Additional and alternative embodiments are also described herein.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A fitting provides a sealed connection in an optionally pressurized fluid conveying system. The fitting can include a face seal surface defining an annular groove having an outer wall that extends inward from the face seal surface, a floor and an inner ramp wall that extends away from the floor toward the face seal surface. The inner ramp wall can be disposed at an acute angle relative to the floor. In some applications, this angle can be about 64° to about 68°. An O-ring can be disposed in the annular groove and under tension due to being stretched over the inner ramp wall. The O-ring can exert a force radially inward toward the longitudinal axis along the inner ramp wall to thereby improve retention of the O-ring in the annular groove.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A fitting provides a sealed connection in an optionally pressurized fluid conveying system. The fitting can include a face seal surface defining an annular groove having an outer wall that extends inward from the face seal surface, a floor and an inner ramp wall that extends away from the floor toward the face seal surface. The inner ramp wall can be disposed at an acute angle relative to the floor. In some applications, this angle can be about 64° to about 68°. An O-ring can be disposed in the annular groove and under tension due to being stretched over the inner ramp wall. The O-ring can exert a force radially inward toward the longitudinal axis along the inner ramp wall to thereby improve retention of the O-ring in the annular groove.

Abstract: A medical data and diagnostics management system for processing classified electrogram (EGM) datasets includes a server system that receives transmissions of classified EGM datasets, each corresponding to an arrhythmic episode detected by an implantable medical device (IMD), and applies a machine-learning model to each classified EGM dataset, thereby determining confidence indicator(s) relating to the IMD classification for each arrhythmic episode. Based upon the confidence indicator(s), the server system generates a set of machine-adjudicated EGM datasets, assigns a ranking score to each machine-adjudicated EGM dataset, and selects for display (for clinical analysis) a subset of the machine-adjudicated EGM datasets based upon their ranking scores. The machine-adjudicated EGM datasets are also stored in a database and further processed to generate diagnostic information and/or diagnostic alerts relating to the arrhythmic episodes detected by the IMD over time.

Abstract: A self-propelled power trowel for finishing a concrete surface is equipped with reversible rotors to allow an operator to reverse the direction of rotation of rotor blades. The trowel includes a rigid frame adapted for operation over a concrete surface, a pair of rotor assemblies having rotor blades tiltably connected to the rigid frame for frictionally contacting the concrete surface and supporting the rigid frame thereabove, a prime mover mounted to the rigid frame and operatively coupled to drive the rotor blades of the rotor assemblies in opposite rotational directions. Synchronous or hydraulic motors are configured for causing, responsive to manual controls, reversal of the direction of rotation of the rotor blades.

Abstract: The present disclosure is directed to systems and methods for high flame temperature oxy-combustion that enables the capture of CO2 cost effectively. One part of the presently disclosed subject matter comprises an annular shroud burner which utilizes a supply of undiluted oxygen and minimal flue gas recycle to generate a high flame temperature to maximize efficiency. The annular shroud burner may deliver oxygen into a combustion zone where mixing of the oxygen and a stream of fuel occurs. Flue gas recycled from the exit of the combustion system serves the dual purpose of conveying the coal into the reaction zone, as well as providing local cooling and protection from high incident heat fluxes through the novel shroud cooling design. The annular shroud burner may be configured to produce an axial jet flame that controls the rate of mixing of oxygen and fuel, thereby extending the heat release. Oxygen and coal may be mixed in a ratio such that peak flame temperatures exceed 4,500° F. (2,482° C.

Abstract: Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein.

Abstract: Methods for improving the antibacterial characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant comprising a silicon nitride ceramic material may be subjected to a surface roughening treatment so as to increase a surface roughness of at least a portion of the biomedical implant to a roughness profile having an arithmetic average of at least about 500 nm Ra. In some implementations, a coating may be applied to a biomedical implant. Such a coating may comprise a silicon nitride ceramic material, and may be applied instead of, or in addition to, the surface roughening treatment process.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: A temperature sensing system for a resistive welding process for a tube performs repeatable temperature measurement using a camera to detect multiple distinct visible light wavelengths even as the ambient environment in the view path changes. Sensed colors in a field of view in the vicinity of a weld are output to a computing element that calculates a corresponding temperature and alerts an operator when the sensed color exceeds a preset color range.

Abstract: Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity of RNA-programmable endonucleases, such as Cas9, or for controlling the activity of proteins comprising a Cas9 variant fused to a functional effector domain, such as a nuclease, nickase, recombinase, deaminase, transcriptional activator, transcriptional repressor, or epigenetic modifying domain. For example, the inventive proteins provided comprise a ligand-dependent intein, the presence of which inhibits one or more activities of the protein (e.g., gRNA binding, enzymatic activity, target DNA binding). The binding of a ligand to the intein results in self-excision of the intein, restoring the activity of the protein.

Abstract: A fitting provides a sealed connection in an optionally pressurized fluid conveying system. The fitting can include a face seal surface defining an annular groove having an outer wall that extends inward from the face seal surface, a floor and an inner ramp wall that extends away from the floor toward the face seal surface. The inner ramp wall can be disposed at an acute angle relative to the floor. In some applications, this angle can be about 64° to about 68°. An O-ring can be disposed in the annular groove and under tension due to being stretched over the inner ramp wall. The O-ring can exert a force radially inward toward the longitudinal axis along the inner ramp wall to thereby improve retention of the O-ring in the annular groove.

Abstract: The present disclosure is directed to systems and methods of managing remote devices. The system can include a server with memory, a detection module, and a collection module. The memory can store a management information base (MIB) having a hierarchical tree of object identifiers and corresponding object values. The detection module can query devices and receive a first object identifier and its first object value, which can vary from those in the MIB; and use patterns to match the first object identifier and object value; and generate an identification of the device from the matches. The collection module can use the identification to select a collection template, which can indicate a subtree of the MIB and a collection pattern; traverse the subtree and identify a second object identifier that matches the collection pattern, and its second object value; and associate the second object value with the first object value.

Abstract: Embodiments described herein can reduce a burden associated with analyzing EGM segments obtained from an IMD that monitors for arrhythmic episodes. Respective EGM data and respective classification data is obtained for each arrhythmic episode detected by the IMD during a period of time. A representative R-R interval or HR for each of the arrhythmic episodes is also obtained, wherein a manner for determining the representative R-R interval or HR depends on the type of the arrhythmic episode, such that for at least two different types of arrhythmic episodes the manners differ. One or more arrhythmic episodes is/are selected for which corresponding EGM segments are to be displayed for each type of arrhythmic episode, wherein the selecting is performed based on the representative R-R intervals or HRs that are determined for the plurality of arrhythmic episodes. Additional and alternative embodiments are also described herein.

Abstract: A carbon sequestration system includes a furnace having an oxy-combustion burner, a mill configured to receive a fuel and to provide the fuel to the oxy-combustion burner, a waste heat recovery exchanger configured to receive a flue gas from the furnace, the flue gas ultimately supplied to one or more of an overfire air port of the furnace, the oxy-combustion burner, the mill, and a CO2 purification unit, the CO2 purification unit configured to produce a purified CO2 stream.