Abstract: The disclosure presents a new computer based model framework to predict drug effects over multiple time and spatial scales from the drug chemistry to the cardiac rhythm. The disclosure presents a new computer based model framework to predict drug effects from the level of the receptor interaction to the cardiac rhythm.

Abstract: The disclosure presents a new computer based model framework to predict drug effects over multiple time and spatial scales from the drug chemistry to the cardiac rhythm. The disclosure presents a new computer based model framework to predict drug effects from the level of the receptor interaction to the cardiac rhythm.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CPTS1, and the treatment of CPTS1-mediated disorders.

Abstract: The disclosure presents a new computer based model framework to predict drug effects over multiple time and spatial scales from the drug chemistry to the cardiac rhythm. The disclosure presents a new computer based model framework to predict drug effects from the level of the receptor interaction to the cardiac rhythm.

Abstract: A system and method for detecting atherosclerotic plaque hemorrhage includes a controller programmed to apply a non-selective inversion recovery RF pulse to a region of interest, apply a plurality of encoding sequences to the region of interest to cause generation of a plurality of echoes during application of each encoding sequence. The controller is further programmed to acquire three dimensional MR data from the region of interest during generation of each of the plurality of echoes, identify a hemorrhage based on the three dimensional MR data, characterize a type of the hemorrhage, and reconstruct an image based on the three dimensional MR data, the image comprising the characterized hemorrhage.

Abstract: A system and method for detecting atherosclerotic plaque hemorrhage includes a controller programmed to apply a non-selective inversion recovery RF pulse to a region of interest, apply a plurality of encoding sequences to the region of interest to cause generation of a plurality of echoes during application of each encoding sequence. The controller is further programmed to acquire three dimensional MR data from the region of interest during generation of each of the plurality of echoes, identify a hemorrhage based on the three dimensional MR data, characterize a type of the hemorrhage, and reconstruct an image based on the three dimensional MR data, the image comprising the characterized hemorrhage.

Abstract: A method of defining a three-dimensional imaging section which comprises displaying a plurality of localizer images of the structure of interest, acquiring operator inputs that designate regions on the plurality of localizer images and that correspond to regions within the structure of interest, and determining a volume based on the regions designated by the operator inputs. The volume defines the three-dimensional imaging section, which is a three-dimensional section of a structure of interest.

Abstract: A method of defining a three-dimensional imaging section which comprises displaying a plurality of localizer images of the structure of interest, acquiring operator inputs that designate regions on the plurality of localizer images and that correspond to regions within the structure of interest, and determining a volume based on the regions designated by the operator inputs. The volume defines the three-dimensional imaging section, which is a three-dimensional section of a structure of interest.