Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.

Abstract: A grommet is provided. The grommet includes a radially inner side wall, a radially outer side wall, and a support structure extending between the radially inner side wall and the radially outer side wall. The support structure includes a plurality of channel walls arranged in a grid-like pattern such that a plurality of hollow passages are defined by the plurality of channel walls.

Abstract: Apparatus and methods provide an electrically isolating clamp that is suitable for use, among other locations, within a composite wing structure and other fuel environments. According to embodiments described herein, the clamp includes a clamp body and cushion. The clamp body is manufactured from a non-conductive material and includes a strap and a base. The cushion may be manufactured from a different non-conductive material to provide at least two layers of electrical isolation between the tube or other object being secured and a structure. The cushion material allows for axial movement of the tube through the cushion. The cushion is disposed between the strap and the base. Shoulder flanges prevent axial movement of the cushion with respect to the clamp body. The clamp may have a cushion retention mechanism to secure the cushion within the strap prior to installation around the tube.

Abstract: Apparatus and methods provide an electrically isolating clamp that is suitable for use, among other locations, within a composite wing structure and other fuel environments. According to embodiments described herein, the clamp includes a clamp body and cushion. The clamp body is manufactured from a non-conductive material and includes a strap and a base. The cushion may be manufactured from a different non-conductive material to provide at least two layers of electrical isolation between the tube or other object being secured and a structure. The cushion material allows for axial movement of the tube through the cushion. The cushion is disposed between the strap and the base. Shoulder flanges prevent axial movement of the cushion with respect to the clamp body. The clamp may have a cushion retention mechanism to secure the cushion within the strap prior to installation around the tube.

Abstract: A tube checking system is made up of a template placed on a flat metallic surface, and a series of adjustable holding fixtures places at selected positions along the template. The template has a computer aided layout of a plan view of a formed tube inscribed on a film with selected check points along the layout showing the height and angle of the tubing above the check point. Each holding fixture is adjustable as to height and angle, is indexed to align to the check point, and has a switchable on off magnet in the base to secure the fixture in position.